Patents by Inventor David A. Jaffray
David A. Jaffray has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20100027744Abstract: A highly compact, high-performance volumetric imaging system is proposed, that is integrated with a multi-source Cobalt-60 gamma irradiator for high throughput, high accuracy and minimally invasive fractioned treatments of intracranial, orbital and head-and-neck targets.Type: ApplicationFiled: July 29, 2008Publication date: February 4, 2010Applicant: Elekta ABInventors: Kevin John Brown, Gregory Bootsma, Mark Ruschin, David A. Jaffray, Per Carlsson
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Publication number: 20100012829Abstract: Various embodiments are described herein for an area integrated fluence monitoring sensor that can be used to measure a radiation dose. The sensor comprises at least one Gradient Ion Chamber (GIC) comprising an ion chamber having a volume gradient across a length or width thereof, a gas or liquid located within the ion chamber and an electrode to detect ions generated within the gas or liquid when the at least one GIC is subjected to an ionizing radiation beam. Various embodiments are also described herein for an Integral Quality Monitoring system and associated method that can be used to measure and monitor the quality of radiation doses provided by a radiation treatment system.Type: ApplicationFiled: July 10, 2007Publication date: January 21, 2010Inventors: Mohammad K. Islam, Bernhard D. Norrlinger, Duncan M. Galbraith, David A. Jaffray, Robert K. Heaton, Jason Smale
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Publication number: 20090116719Abstract: A respiratory marker (40, 140, 240, 340, 440) includes an elongated detectable portion (42, 342, 442) that is operatively coupled with respiration of an imaging subject such that the elongated detectable portion moves with the respiration. The elongated detectable portion is arranged to intersect images acquired by an imaging scanner (10) at different times and at different positions along a scanner axis (20), and is detectable as a marker feature in the images. A marker position finder (52, 54) is configured to determine positions of the marker features in the images.Type: ApplicationFiled: May 1, 2007Publication date: May 7, 2009Applicant: KONINKLIJKE PHILIPS ELECTRONICS N. V.Inventors: David A. Jaffray, Michael R. Kaus, Jeremy D. P. Hoisak, Thomas G. Purdie
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Publication number: 20090074150Abstract: A radiation therapy system that includes a radiation source that moves about a path and directs a beam of radiation towards an object and a cone-beam computer tomography system. The cone-beam computer tomography system includes an x-ray source that emits an x-ray beam in a cone-beam form towards an object to be imaged and an amorphous silicon flat-panel imager receiving x-rays after they pass through the object, the imager providing an image of the object. A computer is connected to the radiation source and the cone beam computerized tomography system, wherein the computer receives the image of the object and based on the image sends a signal to the radiation source that controls the path of the radiation source.Type: ApplicationFiled: November 21, 2008Publication date: March 19, 2009Inventors: David A. Jaffray, John W. Wong, Jeffrey H. Siewerdesen
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Patent number: 7471765Abstract: A radiation therapy system that includes a radiation source that moves about a path and directs a beam of radiation towards an object and a cone-beam computer tomography system. The cone-beam computer tomography system includes an x-ray source that emits an x-ray beam in a cone-beam form towards an object to be imaged and an amorphous silicon flat-panel imager receiving x-rays after they pass through the object, the imager providing an image of the object. A computer is connected to the radiation source and the cone beam computerized tomography system, wherein the computer receives the image of the object and based on the image sends a signal to the radiation source that controls the path of the radiation source.Type: GrantFiled: December 27, 2004Date of Patent: December 30, 2008Assignee: William Beaumont HospitalInventors: David A. Jaffray, John W. Wong, Jeffrey H. Siewerdesen
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Publication number: 20080206131Abstract: Provided are signal modifying compositions for medical imaging comprising a carrier and two or more signal modifying agents specific for two or more imaging modalities. The compositions are characterized by retention efficiency, with respect to the signal modifying agents, which enables prolonged contrast imaging without significant depletion of the signal modifying agents from the carrier. The carriers of the present invention are lipid based or polymer based, the physico-chemical properties of which can be modified to entrap or chelate different signal modifying agents and mixtures thereof and to target specific organs or tumors or tissues within a mammal.Type: ApplicationFiled: February 10, 2006Publication date: August 28, 2008Applicant: University Health NetworkInventors: David Jaffray, Christine Allen, Jinzi Zheng, Raymond Matthew Reilly, Gregory Jason Perkins
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Patent number: 7399977Abstract: A radiation dosimeter system and method for estimating a deposited radiation dose to an object involves locating at least one radiation dosimeter at the object. The radiation dosimeter includes a radiation sensitive medium having an optical property that changes due to the deposited radiation dose. An optical interrogation signal is provided to the radiation dosimeter via an enclosed optical path for interacting with the radiation sensitive medium. During irradiation, the optical interrogation signal is transformed into an optical information signal that encodes an ionizing radiation induced change in the optical property of the radiation sensitive medium. The radiation dosimeter system then processes the optical information signal for estimating the deposited radiation dose.Type: GrantFiled: July 25, 2005Date of Patent: July 15, 2008Assignee: University Health NetworkInventors: Alexandra Rink, David Jaffray, I. Alex Vitkin
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Patent number: 7393329Abstract: Methods and apparatus for delivering radiation therapy to patients during suspended ventilation are provided. The apparatus includes a ventilator assembly having first and second selectively operable valves that independently control inhalation and exhalation of the patient. Both valves are shut to suspend patient ventilation for a period of time. In the methods of the present invention, radiation therapy is administered during this period of suspended patient ventilation.Type: GrantFiled: May 22, 1998Date of Patent: July 1, 2008Assignee: William Beaumont HospitalInventors: John W. Wong, David A. Jaffray, Michael B. Sharpe, John R. Musselwhite
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Publication number: 20080118032Abstract: The invention provides a method and imaging system for operating imaging computed tomography using a radiation source and a plurality of detectors to generate an image of an object. The method includes: defining a desired image characteristics; and performing calculations to determine the pattern of fluence to be applied by the radiation source, to generate said desired image quality or characteristics. Then, the radiation source is modulated, to generate the intended pattern of fluence between the beam source and the object to be imaged. The desired image characteristics can comprise at least one of desired levels of contrast-to-noise ratio (CNR) and signal-to-noise ratio (SNR), and may provide at least one of: desired image quality in at least one defined region of interest; and at least one desired distribution of said image quality.Type: ApplicationFiled: October 5, 2007Publication date: May 22, 2008Inventors: Sean A. Graham, David A. Jaffray, Jeffrey H. Siewerdsen
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Patent number: 7356112Abstract: Artifacts in the reconstructed volume data of cone beam CT systems can be removed by the application of respiration correlation techniques to the acquired projection images. To achieve this, the phase of the patients breathing is monitored while acquiring projection images continuously. On completion of the acquisition, projection images that have comparable breathing phases can be selected from the complete set, and these are used to reconstruct the volume data using similar techniques to those of conventional CT. Any phase can be selected and therefore the effect of breathing can be studied. It is also possible to use a feature in the projection images such as the patient's diaphragm to determine the breathing phase. This feature in the projection images can be used to control delivery of therapeutic radiation dependent on the patient's breathing cycle, to ensure that the tumor is in the correct position when the radiation is delivered.Type: GrantFiled: September 13, 2006Date of Patent: April 8, 2008Assignee: Elekta AB (Pub)Inventors: Kevin John Brown, David Jaffray, Jeffrey H. Siewerdsen, Marcel van Herk, Jan-Jakob Sonke
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Patent number: 7349564Abstract: An apparatus, method and software module for selecting phase-correlated images from the output of a scanner such as a cone beam CT scanner operates by collapsing the images derived from the series from two dimensions to one dimension by summing the intensities of pixels along a dimension transverse to the one dimension, producing a further image from a composite of the one-dimensional images obtained from images in the series, analysing the further image for periodic patterns, and selecting from the series images having like phase in that periodic pattern. If desired, a plurality of reconstructions can be derived at different phases. The analysis of the further image for periodic patterns can include comparing the one-dimensional images therein, to identify a movement of features in that dimension. This allows (inter alia) the accurate determination of the breathing cycle in a patient and a concomitant improvement in the quality of CT scans by using phase-correlated images.Type: GrantFiled: January 20, 2004Date of Patent: March 25, 2008Assignee: Elekta AB (PUBL)Inventors: Lambert Zijp, Kevin John Brown, David Jaffray, Jeffrey H. Siewerdsen, Marcel van Herk, Jan-Jakob Sonke
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Publication number: 20070025496Abstract: Artifacts in the reconstructed volume data of cone beam CT systems can be removed by the application of respiration correlation techniques to the acquired projection images. To achieve this, the phase of the patients breathing is monitored while acquiring projection images continuously. On completion of the acquisition, projection images that have comparable breathing phases can be selected from the complete set, and these are used to reconstruct the volume data using similar techniques to those of conventional CT. Any phase can be selected and therefore the effect of breathing can be studied. It is also possible to use a feature in the projection images such as the patient's diaphragm to determine the breathing phase. This feature in the projection images can be used to control delivery of therapeutic radiation dependent on the patient's breathing cycle, to ensure that the tumor is in the correct position when the radiation is delivered.Type: ApplicationFiled: September 13, 2006Publication date: February 1, 2007Applicant: ELEKTA ABInventors: Kevin Brown, David Jaffray, Jeffrey Siewerdsen, Marcel van Herk, Jan-Jakob Sonke
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Patent number: 7147373Abstract: A system for obtaining coordinate data of a source and detector instrument are described. The system includes a marker assembly having a plurality of markers with a particular geometry, and an energy source for targeting the plurality of markers with energy packets. The system further includes a detector for detecting energy packets after the plurality of markers have interacted therewith, and an image device for forming image data of the plurality of markers from the energy packets detected by the detector. A calibration module for utilizes the particular geometry of the plurality of markers and the image data to non-iteratively determine coordinate data.Type: GrantFiled: August 9, 2004Date of Patent: December 12, 2006Assignee: University Health NetworkInventors: Young-bin Cho, Douglas J. Moseley, Jeffrey H. Siewerdsen, David A. Jaffray
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Publication number: 20060050847Abstract: A radiation therapy system that includes a radiation source that moves about a path and directs a beam of radiation towards an object and a cone-beam computer tomography system. The cone-beam computer tomography system includes an x-ray source that emits an x-ray beam in a cone-beam form towards an object to be imaged and an amorphous silicon flat-panel imager receiving x-rays after they pass through the object, the imager providing an image of the object. A computer is connected to the radiation source and the cone beam computerized tomography system, wherein the computer receives the image of the object and based on the image sends a signal to the radiation source that controls the path of the radiation source.Type: ApplicationFiled: December 27, 2004Publication date: March 9, 2006Inventors: David Jaffray, John Wong, Jeffrey Siewerdesen
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Publication number: 20060017009Abstract: A radiation dosimeter system and method for estimating a deposited radiation dose to an object involves locating at least one radiation dosimeter at the object. The radiation dosimeter includes a radiation sensitive medium having an optical property that changes due to the deposited radiation dose. An optical interrogation signal is provided to the radiation dosimeter via an enclosed optical path for interacting with the radiation sensitive medium. During irradiation, the optical interrogation signal is transformed into an optical information signal that encodes an ionizing radiation induced change in the optical property of the radiation sensitive medium. The radiation dosimeter system then processes the optical information signal for estimating the deposited radiation dose.Type: ApplicationFiled: July 25, 2005Publication date: January 26, 2006Inventors: Alexandra Rink, David Jaffray, I. Alex Vitkin
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Publication number: 20050117708Abstract: A system for obtaining coordinate data of a source and detector instrument are described. The system includes a marker assembly having a plurality of markers with a particular geometry, and an energy source for targeting the plurality of markers with energy packets. The system further includes a detector for detecting energy packets after the plurality of markers have interacted therewith, and an image device for forming image data of the plurality of markers from the energy packets detected by the detector. A calibration module for utilizes the particular geometry of the plurality of markers and the image data to non-iteratively determine coordinate data.Type: ApplicationFiled: August 9, 2004Publication date: June 2, 2005Inventors: Young-bin Cho, Douglas Moseley, Jeffrey Siewerdsen, David Jaffray
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Patent number: 6842502Abstract: A radiation therapy system that includes a radiation source that moves about a path and directs a beam of radiation towards an object and a cone-beam computer tomography system. The cone-beam computer tomography system includes an x-ray source that emits an x-ray beam in a cone-beam form towards an object to be imaged and an amorphous silicon flat-panel imager receiving x-rays after they pass through the object, the imager providing an image of the object. A computer is connected to the radiation source and the cone beam computerized tomography system, wherein the computer receives the image of the object and based on the image sends a signal to the radiation source that controls the path of the radiation source.Type: GrantFiled: February 16, 2001Date of Patent: January 11, 2005Assignee: Dilliam Beaumont HospitalInventors: David A. Jaffray, John W. Wong, Jeffrey H. Siewerdesen
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Publication number: 20040234115Abstract: An apparatus, method and software module for selecting phase-correlated images from the output of a scanner such as a cone beam CT scanner operates by collapsing the images derived from the series from two dimensions to one dimension by summing the intensities of pixels along a dimension transverse to the one dimension, producing a further image from a composite of the one-dimensional images obtained from images in the series, analysing the further image for periodic patterns, and selecting from the series images having like phase in that periodic pattern. If desired, a plurality of reconstructions can be derived at different phases. The analysis of the further image for periodic patterns can include comparing the one-dimensional images therein, to identify a movement of features in that dimension. This allows (inter alia) the accurate determination of the breathing cycle in a patient and a concomitant improvement in the quality of CT scans by using phase-correlated images.Type: ApplicationFiled: January 20, 2004Publication date: November 25, 2004Inventors: Lambert Zijp, Kevin John Brown, David Jaffray, Jeffrey H. Siewerdsen, Marcel van Herk, Jan-Jakob Sonke
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Publication number: 20040218719Abstract: Artefacts in the reconstructed volume data of cone beam CT systems can be removed by the application of respiration correlation techniques to the acquired projection images. To achieve this, the phase of the patients breathing is monitored while acquiring projection images continuously. On completion of the acquisition, projection images that have comparable breathing phases can be selected from the complete set, and these are used to reconstruct the volume data using similar techniques to those of conventional CT. Any phase can be selected and therefore the effect of breathing can be studied. It is also possible to use a feature in the projection image(s) such as the patient's diaphragm to determine the breathing phase. This feature in the projection images can be used to control delivery of therapeutic radiation dependent on the: patient's breathing cycle, to ensure that the tumour is in the correct position when the radiation is delivered.Type: ApplicationFiled: January 20, 2004Publication date: November 4, 2004Inventors: Kevin John Brown, David Jaffray, Jeffrey H. Siewerdsen, Marcel van Herk, Jan-Jakob Sonke
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Publication number: 20030007601Abstract: A radiation therapy system that includes a radiation source that moves about a path and directs a beam of radiation towards an object and a cone-beam computer tomography system. The cone-beam computer tomography system includes an x-ray source that emits an x-ray beam in a cone-beam form towards an object to be imaged and an amorphous silicon flat-panel imager receiving x-rays after they pass through the object, the imager providing an image of the object. A computer is connected to the radiation source and the cone beam computerized tomography system, wherein the computer receives the image of the object and based on the image sends a signal to the radiation source that controls the path of the radiation source.Type: ApplicationFiled: February 16, 2001Publication date: January 9, 2003Inventors: David A. Jaffray, John W. Wong, Jeffrey H. Siewerdsen