Abstract: A system and method are presented for managing service transactions. The method includes defining a project including a plurality of activities and qualifications and preparing a Request for Proposal (RFP) from the project definition. A plurality of service providers are notified of the RFP. Proposals are received from prospective service providers. The received proposals are ranked based on evaluations of past performance of the prospective service providers. The evaluations include weighted categories of activities and qualifications of the service providers, where the weight is a percentage value corresponding to a relative importance of the activities and qualification to the project. The method further includes selecting at least one of the prospective service providers to perform the project, negotiating terms of performance with the prospective service providers, monitoring performance of the project and, upon completion of the project, requesting evaluations of the performance.

Abstract: A method for production of a form-specific and/or inhibitory antibody against a cytochrome P450 protein is disclosed. The method includes the steps of selecting a cytochrome P450 protein for which a form-specific and/or inhibitory antibody is needed. The amino acid sequence of the selected cytochrome P450 protein is determined and aligned with a comparison amino acid sequence using an alignment algorithm. A peptide sequence corresponding to a region of a substrate recognition site is identified and a peptide of the selected sequence prepared. Using the peptide as an immunogen, an inhibitory and/or form-specific antibody is produced.