Abstract: A system and method for a patient-specific surgical procedure is disclosed. The method may include preparing a request for a customized surgical plan, loading the customized surgical plan onto an augmented reality device, and performing an orthopaedic surgical procedure with the augmented reality device in accordance with the customized surgical plan.

Abstract: An adapter assembly for transmitting a drive force from a pile driving system defining a drive axis to a pile defining a pile axis comprising a base assembly and an adapter assembly. The base assembly is operatively supported such that the drive force is transmitted to the base assembly. The adapter assembly comprises a plate member, a skirt member defining a skirt chamber, and an adapter connector configured to support the skirt member relative to the base assembly, the plate member, and the pile member. The adapter assembly substantially aligns the drive axis with the pile axis. The drive force is transmitted from the base assembly to the plate member. The pile is received within the skirt chamber such that the drive force is transmitted from the plate member to the pile. The skirt member is substantially isolated from the drive force.

Abstract: An adapter assembly for transmitting a drive force from a pile driving system defining a drive axis to a pile defining a pile axis comprising a base assembly and an adapter assembly. The base assembly is operatively supported such that the drive force is transmitted to the base assembly. The adapter assembly comprises a plate member, a skirt member defining a skirt chamber, and an adapter connector configured to support the skirt member relative to the base assembly, the plate member, and the pile member. The adapter assembly substantially aligns the drive axis with the pile axis. The drive force is transmitted from the base assembly to the plate member. The pile is received within the skirt chamber such that the drive force is transmitted from the plate member to the pile. The skirt member is substantially isolated from the drive force.

Abstract: A clamp system for an elongate member, comprising first and second clamp members, an actuator member, and an actuator system. The actuator member defines an actuator cam surface and is supported for movement between first and second actuator positions. The second clamp member defines a clamp cam surface and is supported for movement between first and second clamp positions. The actuator system displaces the actuator member between first and second actuator positions. As the actuator member moves from the first actuator position to the second actuator position, the actuator cam surface engages the clamp cam surface to cause the second clamp member to move towards the first clamp member, thereby clamping a portion of the elongate member between the first and second clamp members.

Abstract: An adapter assembly for transmitting a drive force from a pile driving system defining a drive axis to a pile defining a pile axis comprising a base assembly and an adapter assembly. The base assembly is operatively supported such that the drive force is transmitted to the base assembly. The adapter assembly comprises a plate member, a skirt member defining a skirt chamber, and an adapter connector configured to support the skirt member relative to the base assembly, the plate member, and the pile member. The adapter assembly substantially aligns the drive axis with the pile axis. The drive force is transmitted from the base assembly to the plate member. The pile is received within the skirt chamber such that the drive force is transmitted from the plate member to the pile. The skirt member is substantially isolated from the drive force.

Abstract: This invention relates to screening assay methods that can be applied to broad members of the protein kinase gene family and are useful in the detection and evaluation of kinase inhibitors.

Abstract: A device and method for accessing a pericardial space of the heart includes a shaft having a cavity at a distal end, a suction lumen terminating in a distal port within the cavity and a hollow needle having a distal tip extending into the cavity. The cavity may be a recess in the shaft into which the distal tip of the needle fixedly protrudes. In other embodiments, the cavity is formed by an inflatable member positioned at the distal end of the shaft and the needle is slidable relative to the shaft. Suction is applied at the cavity to draw a pericardial bleb. The needle pierces the pericardial bleb for accessing the pericardial space and also facilitates delivery of payloads into the pericardial space.

Abstract: An adapter for an implantable cardiac lead, the adapter having a housing with an interior axial opening and an outer surface. The interior axial opening is configured to receive a mating terminal end of the implantable cardiac lead. A plurality of inner contacts are positioned within the interior axial opening and a plurality of outer contacts are positioned on the outer surface. Each of the inner contacts is electrically connected to an outer contact. The inner contacts are configured to electrically link with contacts on the mating terminal end of the implantable cardiac lead when the mating terminal end of the implantable cardiac lead is positioned within the interior opening. The outer surface is configured for connection of the outer contacts to a testing cable, the testing cable providing electrical connectivity with a device for testing the electrical continuity of the cardiac lead. An assembly including an adapter may be used to connect implanted cardiac leads with a testing device.

Abstract: The present invention is a lead for use in connection with a myocardial lead attachment system of the type having an anchor for engaging the heart and a tether extending from the anchor. The lead includes a lead body having a proximal end, a distal end and a lumen for accepting the tether. A tapered tip is separate from the lead and positioned adjacent the distal end of the lead. The tip has a longitudinal through-hole for accepting the tether.

Abstract: The present invention is a myocardial lead attachment system and method for securing a distal end of a lead within the myocardium of a patient's heart. The system includes an anchor, a tether coupled at a distal end to the anchor and a lead body. The lead body has a proximal end, a distal end, and a lumen extending therethrough for receiving the tether. A fixation mechanism is at the distal end of the lead body, and is adapted to collapse to a first configuration during implantation and deploy to a second configuration after implantation.