Patents by Inventor David Alan Mead

David Alan Mead has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20100291638
    Abstract: Thermostable viral and microbial polymerases exhibiting a combination of activities selected from proofreading (3?-5?) exonuclease activity, nick translating (5?-3?) nuclease activity, synthetic primer-initiated polymerase activity, nick-initiated polymerase activity, reverse transcriptase activity, strand displacement activity, terminal transferase activity, primase activity, and/or efficient incorporation of chain terminating analogs. Some of the polymerases provided herein include a first motif and a second motif. The first motif preferably has the sequence X1X2X3DX4PX5IELRX6X7X8, wherein X1 is I or V; X4 is F or Y; X8 is G or A; and X2, X3, X5, X6, and X7 are any amino acid. The second motif preferably has the sequence RX9X10X11KSANX12GX13X14YG, wherein X11 is G or A; X12 is F, L, or Y; X13 is L or V; X14 is I or L; and X9 and X10 are any amino acid.
    Type: Application
    Filed: April 15, 2010
    Publication date: November 18, 2010
    Inventors: Thomas William Schoenfeld, Nicholas Hermersmann, Darby Renneckar, David Alan Mead
  • Publication number: 20040244065
    Abstract: The present invention relates to systems, methods, and compositions for cloning and sequencing insert nucleic acid sequences. In particular, the present invention provides vectors and vector components configured for multiplex cloning, multiplex sequencing, and fixed orientation cloning. The present invention also provides vectors and vector components that allow insert sequences that are deleterious to a host cell to be successfully cloned.
    Type: Application
    Filed: February 20, 2004
    Publication date: December 2, 2004
    Inventors: David Alan Mead, Ronald Godiska
  • Publication number: 20040229359
    Abstract: The present invention relates to systems, methods, and compositions for cloning and sequencing insert nucleic acid sequences. In particular, the present invention provides vectors and vector components configured for multiplex cloning, multiplex sequencing, and fixed orientation cloning. The present invention also provides vectors and vector components that allow insert sequences that are deleterious to a host cell to be successfully cloned.
    Type: Application
    Filed: December 19, 2003
    Publication date: November 18, 2004
    Inventors: David Alan Mead, Ronald Godiska
  • Patent number: 6709861
    Abstract: The present invention relates to systems, methods, and compositions for cloning and sequencing insert nucleic acid sequences. In particular, the present invention provides vectors and vector components configured for multiplex cloning, multiplex sequencing, and fixed orientation cloning. The present invention also provides vectors and vector components that allow insert sequences that are deleterious to a host cell to be successfully cloned.
    Type: Grant
    Filed: November 15, 2001
    Date of Patent: March 23, 2004
    Assignee: Lucigen Corp.
    Inventors: David Alan Mead, Ronald Godiska
  • Publication number: 20040038401
    Abstract: The present invention relates to systems, methods, and compositions for cloning and sequencing insert nucleic acid sequences. In particular, the present invention provides vectors and vector components configured for multiplex cloning, multiplex sequencing, and fixed orientation cloning. The present invention also provides vectors and vector components that allow insert sequences that are deleterious to a host cell to be successfully cloned.
    Type: Application
    Filed: November 15, 2001
    Publication date: February 26, 2004
    Applicant: Lucigen Corporation
    Inventors: David Alan Mead, Ronald Godiska