Patents by Inventor David B. Murphey

David B. Murphey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fused bicycloheterocycle substituted quinuclidine derivatives
    Patent number: 7655657
    Abstract: Compounds of formula (II): known as: 5-{6-[(3R)-1-azabicyclo[2.2.2]oct-3-yloxy]pyridazin-3-yl}-1-H-indole salt with (2R, 3R)-2,3-dihydroxybutanedioic acid (1:1).
    Type: Grant
    Filed: April 26, 2007
    Date of Patent: February 2, 2010
    Assignee: Abbott Laboratories
    Inventors: Eric J. Stoner, Alan Christesen, Ahmad Y. Sheikh, Xiu Chun Wang, Agnes Pal, David B. Murphey, Jianguo Ji, Devalina Law, Daozhong Zou
  • Synthesis and isolation of N-(aryl or heteroaryl)-alkyl-N-hydroxyurea
    Patent number: 6080874
    Abstract: The present invention provides a simple, 1-step process for preparing a N-(aryl or heteroaryl)-hydroxyurea comprising reacting the corresponding alcohol, ester or ether with hydroxyurea and acid. This reaction is particularly useful for preparing a benzo[b]thienyl substituted N-hydroxyurea of formula: ##STR1## from compound 1: ##STR2## by reacting compound 1 with hydroxyurea and acid. R.sup.1 is selected from the group consisting of hydrogen, 1-6 carbon alkyl, 1-6 carbon alkoxy, and halogen; R.sup.2 is an 1-4 carbon alkyl; and R.sup.3 is selected from the group consisting of hydrogen, acyl, methyl, ethyl and mixtures thereof. Additional steps to isolate the pure bulk product follow.
    Type: Grant
    Filed: September 25, 1998
    Date of Patent: June 27, 2000
    Assignee: Abbott Laboratories
    Inventors: John E. Hengeveld, Elise H. Leese, Brian S. Moon, Dennis M. Abad, Kimberly A. Allen, Philip E. Bauer, David B. Murphey, Brian T. Fohey, Richard R. Copp, Jr., Greg S. Lannoye, Rodney M. Mittag