Patents by Inventor David C. Henke

David C. Henke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for treating mucosal tissue disorders
    Patent number: 11938166
    Abstract: The present invention provides compositions and formulations comprising glutathione with or without thiocyanate and methods of use thereof to treat diseases and disorders in mucosal/epithelial tissue.
    Type: Grant
    Filed: June 15, 2021
    Date of Patent: March 26, 2024
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Roland R. Arnold, David C. Henke
  • METHODS AND COMPOSITIONS FOR TREATING MUCOSAL TISSUE DISORDERS
    Publication number: 20220143129
    Abstract: The present invention provides compositions and formulations comprising glutathione with or without thiocyanate and methods of use thereof to treat diseases and disorders in mucosal/epithelial tissue.
    Type: Application
    Filed: June 15, 2021
    Publication date: May 12, 2022
    Inventors: Roland R. Arnold, David C. Henke
  • Methods and compositions for treating mucosal tissue disorders
    Patent number: 11058743
    Abstract: The present invention provides compositions and formulations comprising glutathione with or without thiocyanate and methods of use thereof to treat diseases and disorders in mucosal/epithelial tissue.
    Type: Grant
    Filed: August 1, 2019
    Date of Patent: July 13, 2021
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Roland R. Arnold, David C. Henke
  • METHODS AND COMPOSITIONS FOR TREATING MUCOSAL TISSUE DISORDERS
    Publication number: 20200179478
    Abstract: The present invention provides compositions and formulations comprising glutathione with or without thiocyanate and methods of use thereof to treat diseases and disorders in mucosal/epithelial tissue.
    Type: Application
    Filed: August 1, 2019
    Publication date: June 11, 2020
    Inventors: Roland R. Arnold, David C. Henke
  • Methods and compositions for treating mucusal tissue disorders
    Patent number: 10406200
    Abstract: The present invention provides compositions and formulations comprising glutathione with or without thiocyanate and methods of use thereof to treat diseases and disorders in mucosal/epithelial tissue.
    Type: Grant
    Filed: February 10, 2016
    Date of Patent: September 10, 2019
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Roland R. Arnold, David C. Henke
  • METHODS AND COMPOSITIONS FOR TREATING MUCUSAL TISSUE DISORDERS
    Publication number: 20160228490
    Abstract: The present invention provides compositions and formulations comprising glutathione with or without thiocyanate and methods of use thereof to treat diseases and disorders in mucosal/epithelial tissue.
    Type: Application
    Filed: February 10, 2016
    Publication date: August 11, 2016
    Inventors: Roland R. Arnold, David C. Henke
  • Methods and compositions for treating mucosal tissue disorders
    Patent number: 9308234
    Abstract: The present invention provides compositions and formulations comprising glutathione with or without thiocyanate and methods of use thereof to treat diseases and disorders in mucosal/epithelial tissue.
    Type: Grant
    Filed: July 29, 2014
    Date of Patent: April 12, 2016
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Roland R. Arnold, David C. Henke
  • Methods and Compositions for Treating Mucosal Tissue Disorders
    Publication number: 20150010654
    Abstract: The present invention provides compositions and formulations comprising glutathione with or without thiocyanate and methods of use thereof to treat diseases and disorders in mucosal/epithelial tissue.
    Type: Application
    Filed: July 29, 2014
    Publication date: January 8, 2015
    Inventors: Roland R. Arnold, David C. Henke
  • Method of treating retained asthma pulmonary secretions
    Patent number: 5849706
    Abstract: A method of facilitating the clearance of retained pulmonary secretions in a subject using lantibiotics is disclosed. The method comprises administering to the lungs of the subject an effective amount of a lantibiotic. The lantibiotic is preferably administered by topically applying it to the respiratory epithelia, such as by generating an aerosol thereof which is then inhaled by the subject. A preferred lantibiotic for carrying out the present invention is duramycin. The method may be used in treating disorders such as cystic fibrosis, chronic bronchitis, and asthma. Also disclosed is a method of combatting tuberculosis comprising administering a lantibiotic to a subject in need of such treatment.
    Type: Grant
    Filed: January 28, 1998
    Date of Patent: December 15, 1998
    Assignees: Molichem Medicines, Inc., The University of North Carolina at Chapel Hill
    Inventors: Luis Miguel Molina y Vedia, Monroe Jackson Stutts, Richard C. Boucher, Jr., David C. Henke
  • Method of treating retained pulmonary secretions
    Patent number: 5716931
    Abstract: A method of facilitating the clearance of retained pulmonary secretions in a subject using lantibiotics is disclosed. The method comprises administering to the lungs of the subject an effective amount of a lantibiotic. The lantibiotic is preferably administered by topically applying it to the respiratory epithelia, such as by generating an aerosol thereof which is then inhaled by the subject. A preferred lantibiotic for carrying out the present invention is duramycin. The method may be used in treating disorders such as cystic fibrosis, chronic bronchitis, and asthma. Also disclosed is a method of combatting tuberculosis comprising administering a lantibiotic to a subject in need of such treatment.
    Type: Grant
    Filed: May 2, 1995
    Date of Patent: February 10, 1998
    Assignee: Molichem Medicines, Inc.
    Inventors: Luis Miguel Molina y Vedia, Monroe Jackson Stutts, Richard C. Boucher, Jr., David C. Henke
  • Method of treating retained pulmonary secretions
    Patent number: 5683675
    Abstract: A method of facilitating the clearance of retained pulmonary secretions in a subject using lantibiotics is disclosed. The method comprises administering to the lungs of the subject an effective amount of a lantibiotic. The lantibiotic is preferably administered by topically applying it to the respiratory epithelia, such as by generating an aerosol thereof which is then inhaled by the subject. A preferred lantibiotic for carrying out the present invention is duramycin. The method may be used in treating disorders such as cystic fibrosis, chronic bronchitis, and asthma. Also disclosed is a method of combatting tuberculosis comprising administering a lantibiotic to a subject in need of such treatment.
    Type: Grant
    Filed: May 2, 1995
    Date of Patent: November 4, 1997
    Assignee: Molichem Medicines, Inc.
    Inventors: Luis Miguel Molina y Vedia, Monroe Jackson Stutts, Richard C. Boucher, Jr., David C. Henke
  • Method of treating retained pulmonary secretions
    Patent number: 5651957
    Abstract: A method of facilitating the clearance of retained pulmonary secretions in a subject using lantibiotics is disclosed. The method comprises administering to the lungs of the subject an effective amount of a lantibiotic. The lantibiotic is preferably administered by topically applying it to the respiratory epithelia, such as by generating an aerosol thereof which is then inhaled by the subject. A preferred lantibiotic for carrying out the present invention is duramycin. The method may be used in treating disorders such as cystic fibrosis, chronic bronchitis, and asthma. Also disclosed is a method of combatting tuberculosis comprising administering a lantibiotic to a subject in need of such treatment.
    Type: Grant
    Filed: May 2, 1995
    Date of Patent: July 29, 1997
    Assignee: Molichem Medicines, Inc.
    Inventors: Luis Miguel Molina y Vedia, Monroe Jackson Stutts, Richard C. Boucher, Jr., David C. Henke
  • Method of treating retained pulmonary secretions
    Patent number: 5512269
    Abstract: A method of facilitating the clearance of retained pulmonary secretions in a subject using lantibiotics is disclosed. The method comprises administering to the lungs of the subject an effective amount of a lantibiotic. The lantibiotic is preferably administered by topically applying it to the respiratory epithelia, such as by generating an aerosol thereof which is then inhaled by the subject. A preferred lantibiotic for carrying out the present invention is duramycin. The method may be used in treating disorders such as cystic fibrosis, chronic bronchitis, and asthma. Also disclosed is a method of combatting tuberculosis comprising administering a lantibiotic to a subject in need of such treatment.
    Type: Grant
    Filed: June 9, 1993
    Date of Patent: April 30, 1996
    Assignees: Burroughs Wellcome, Co., University of North Carolina at Chapel Hill
    Inventors: Luis M. Molina y Vedia, Monroe J. Stutts, Richard C. Boucher, Jr., David C. Henke