Patents by Inventor David C. Wyllie

David C. Wyllie has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immobilized metal, affinity chromatography
    Patent number: 5932102
    Abstract: A method for purifying protein containing histidine residues using immobilized metal, affinity chromatography. The hydrophilic index of the histidine residues is determined (HI). If the HI is at least 2 the pH of the solution containing the protein is adjusted to about 6.75 to 7.2 and applied to the IMAC column such that the protein binds to the column.
    Type: Grant
    Filed: January 12, 1998
    Date of Patent: August 3, 1999
    Assignee: Schering Corporation
    Inventors: David C. Wyllie, John Chu-Tay Tang