Abstract: The present invention concerns a novel in vitro assay for determining the invasive ability of brain tumour cells, in particular brain tumour stem cells. This new assay, called 3D invasion assay, is based on the analysis and comparison of the area of neurospheres grown in vitro into a Matrigel extracellular-like matrix. The invention also concerns the use of said assay for diagnosing metastatic brain tumour in subjects, for determining its prognosis, as well as for the monitoring, for the stratification, for identifying subjects at risk of metastasis, and/or predicting the metastasis-associated risk in subjects diagnosed with brain tumour.

Abstract: The present invention is directed to methods for improving male fertility inter alia by increasing sperm count in a male subject. The methods of the invention comprise applying a positive electrical current below sensation level to at least one site of a scrotum of a subject in need thereof.

Abstract: The present invention is directed to methods for improving male fertility inter alia by increasing sperm count in a male subject. The methods of the invention comprise applying a positive electrical current below sensation level to at least one site of a scrotum of a subject in need thereof.

Abstract: A heater and humidifier for use with a breathing mask or other breathing apparatus, to avoid unpleasant and injurious effects of prolonged breathing of cold dry air, or other breathing gas mixture. The action is accomplished by injection and combustion of hydrogen directly in the breathing gas, and is carried out in a safe manner adjacent to or in the breathing mask. In addition to the heating effect, the hydrogen combines with oxygen in the breathing gas to produce moisture. The apparatus is adaptable to use under water, or in the atmosphere at any altitude and can be operated without a special power source.