Abstract: Systems and methods are provided for relevance-based media content discovery. Relevance scores for segments of a media asset are calculated based on a time amount that at least one viewer has viewed the segments of the media asset. Segments are then chosen for display based on the relevance score. Users may select segments based on representative images of the segments.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for generating images. In one aspect, a method includes: receiving an input text prompt including a sequence of text tokens in a natural language; processing the input text prompt using a text encoder neural network to generate a set of contextual embeddings of the input text prompt; and processing the contextual embeddings through a sequence of generative neural networks to generate a final output image that depicts a scene that is described by the input text prompt.

Abstract: Anti-PVRIG and anti-TIGIT antibodies are provided.

Abstract: A computer-implemented method of delivering hash values from a hashing device to a hashing pool, wherein the method comprises: obtaining a candidate block header for a candidate block of a blockchain; performing a plurality of hashing operations on the candidate block header to generate a plurality of candidate proof-of-work (PoW) solutions; encrypting each of the candidate PoW solutions with an encryption key; and sending the encrypted candidate PoW solutions to a hashing pool, wherein the hashing pool configured to decrypt the encrypted candidate PoW solutions.

Abstract: The present disclosure provides creatine prodrug analogs and their compositions useful for the treatment of creatine deficiencies.

Abstract: The present invention features interferon-free therapies for the treatment of HCV. Preferably, the treatment is over a shorter duration of treatment, such as no more than 12 weeks. In one aspect, the treatment comprises administering at least two direct acting antiviral agents to a subject with HCV infection, wherein the treatment lasts for 12 weeks and does not include administration of either interferon or ribavirin, and said at least two direct acting antiviral agents comprise (a) Compound 1 or a pharmaceutically acceptable salt thereof and (b) Compound 2 or a pharmaceutically acceptable salt thereof.

Abstract: Anti-PVRIG and anti-TIGIT antibodies are provided.

Abstract: A laser leveling tool comprising: gesture control means comprises at least one sensor adapted to sense gestures and/or movements of a user; and a controller in communication with the gesture control means for receiving signals from the sensor and generating control commands for the tool based on the received signals, the control commands comprising at least ON/OFF states of laser beam patterns that the tool can project.

Abstract: A cosmetic composition including about 0.01 to about 3 wt. % of retinol; about 0.01 to about 1 wt. % of pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate; about 0.01 to about 3 wt. % of trisodium ethylenediamine disuccinate; about 0.5 to about 7 wt. % of polyglyceryl-3 methylglucose distearate; about 0.9 to about 7 wt. % of sodium polyacrylate; about 0.5 to about 8 wt. % of an oil phase; and water, where all weight percentages are based on the total weight of the cosmetic composition. Additionally, the cosmetic composition is typically formulated to form an oil-in-water emulsion. Methods for treating damaged skin with cosmetic compositions are also disclosed herein.

Abstract: The instant disclosure relates to cosmetic compositions comprising: (i) compounds of Thiopyridinone type; (ii) one or more hydrophilic antioxidants; and wherein the compound of thiopyridinone type and the one or more hydrophilic antioxydants are present in the composition in amounts sufficient to produce stability of (i) and (ii).

Abstract: The instant disclosure relates to cosmetic compositions and methods of using the cosmetic compositions to benefit the skin. The cosmetic compositions typically include: (a) compounds of thiopyridinone type; (b) and one or more UV boosters. The compositions provide multiple benefits to skin. For example, the compositions are particularly useful for whitening the skin, and for improving skin's appearance.

Abstract: The instant disclosure relates to oil-in-water compositions comprising: (i) compound of thiopyridinone type; (ii) a blend of natural emulsifiers; wherein the oil-in-water cosmetic composition is physically stable.

Abstract: An oil-in-water cosmetic composition comprising: compound of thipyridinone type; one or more Polyglyceryl Fatty Acid Ester; an oil phase; and wherein the oil-in-water cosmetic composition is a macroemulsion and wherein the compound of thipyridinone type penetrates rapidly and in a high amount.

Abstract: A distributed key management system, which contains a server, a plurality of key-holding devices adapted to communicate with the server; and a key-requesting device adapted to communicate with the server. Each one of the plurality of key-holding devices is adapted to hold a different fragment of a private key. The server is adapted to reconstruct the private key based on the fragments received from the plurality of key-holding devices. The key-requesting device is adapted to obtain the private key from the server. The systems according to the invention provide a zero-trust model key management scheme and would eliminate the risk of key leakage to unauthorized person while providing flexibility of authorizing devices.

Abstract: A cosmetic composition in the form of a direct oil in water creamy emulsion includes water and oily phases, the water phase including a salt-stable polymeric system that includes polyacrylate crosspolymer-6, xanthan gum, and one or more clay, and high amounts of Vitamin C, oils and emulsifiers and confers a pleasant feel upon application with a smooth, gliding texture and does not severely “pill,” “ball” or “noodle” when applied to the skin. The cosmetic composition does not phase separate into solid/liquid or oily and water based layers.

Abstract: The present disclosure relates to stable cosmetic compositions containing high amounts of ceramide NP. The cosmetic compositions further include high amounts of hydroxypropyl tetrahydropyrantriol, a plurality of emulsifiers, fatty alcohols, fatty compounds, and water. Methods for stabilizing the cosmetic compositions containing high amounts of ceramide NP and methods for treating the skin with the cosmetic compositions is also described.

Abstract: An electrical connector for high speed signals. The connector has multiple conductive elements that may serve as signal or ground conductors. A member formed with lossy material and conductive compliant members may be inserted in the connector. The conductive compliant members may be aligned with conductive elements of the connector configured as ground conductors. For a connector configured to carry differential signals, the ground conductors may separate pairs of signal conductors. The member may further include a conductive web, embedded within the lossy material, that interconnects the conductive compliant members. For a receptacle connector, the conductive elements may have mating contact portions aligned along opposing surfaces of a cavity. The conductive elements may have contact tails for attachment to a printed circuit board and intermediate portions connecting the mating contact portions and the contact tails. The conductive compliant members may press against the intermediate portions.

Abstract: An omnichannel intelligent negotiation assistant for generating timely, contextual negotiation assistance to a negotiator. The invention includes a semantic term extractor for converting a contract document into a negotiable term sheet. An omnichannel listener captures all negotiation inputs associated with a negotiation event, sequences each negotiation input by time, and analyzes the sentiment of the negotiation inputs in the context of a term sheet. The resulting annotated negotiation input stream is processed by an intervention generator that includes models of the parties and the negotiation itself as well as a referent negotiation model. The intervention generator includes a game theoretic model that, in concert with a trade-off matrix, allows the intervention generator to produce timely contextual interventions to the negotiator that assist in achieving a superior resulting negotiated agreement.

Abstract: A computer-implemented method of generating random numbers based on blockchain transactions, wherein the method is performed by a generating party and comprises: obtaining a candidate block header, wherein the candidate block header is based on a set of blockchain transactions; applying a hash function to at least the candidate block header one or more times, wherein each application of the hash function to at least the candidate block header generates a respective hash digest; generating one or more random numbers, wherein each random number is generated based on a respective hash digest; and outputting the one or more random numbers to one or more consuming devices.