Patents by Inventor David E. Lewis

David E. Lewis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190263765
    Abstract: A composition is provided that, when utilized in combination with a coumarin anticoagulant, greatly improves the anticoagulant effects of the anticoagulant in mammalian subjects. The composition is a compound having a naphthohydroquinone ring system substantially similar to the ring system of the reduced form of vitamin K1 and has the general formula: where n is 1 or 2, where R1 and R4 are hydrogen or acyl, R2 is a hydrogen or saturated or unsaturated alkyl group with up to 6 carbons, and R3 is a hydrogen or saturated or unsaturated alkyl group with up to 6 carbons, or R2 and R3 are part of a cyclic or polycyclic ring system.
    Type: Application
    Filed: February 22, 2019
    Publication date: August 29, 2019
    Inventor: David E. Lewis
  • Patent number: 8853454
    Abstract: The present invention relates to quaternary ammonium salts and their use as mold inhibitors. The quaternary salts can be prepared by a chloride ion-promoted reaction between a tertiary amine and an alcohol or polyol in strong acid solution. The quaternary ammonium salts can be applied to a substrate in order to impart anti-mold properties to the substrate. Preferably, the quaternary ammonium salt compounds are applied to paper substrates in an amount of about 1000 ppm. Preferably, the quaternary ammonium salts compounds are applied as mixtures of more than one quaternary ammonium salt compound. The treated substrate does not require encapsulators, binders, or retention aids.
    Type: Grant
    Filed: August 29, 2007
    Date of Patent: October 7, 2014
    Assignee: Mionix Corporation
    Inventors: Maurice C. Kemp, David E. Lewis
  • Patent number: 8765982
    Abstract: A composition is provided that, when utilized in combination with warfarin, greatly improves the anticoagulant effects of warfarin in mammalian subjects. The composition is a compound having a naphthohydroquinone ring system substantially similar to the ring system of the reduced form of vitamin K1 and has the general formula: where R1 and R4 are hydrogen or acyl, R2 is a saturated or unsaturated alkyl group with up to 6 carbons, and R3 is a saturated or unsaturated alkyl group with up to 20 carbons, or R2 and R3 are part of a cyclic or polycyclic ring system.
    Type: Grant
    Filed: September 30, 2010
    Date of Patent: July 1, 2014
    Assignee: Marshfield Clinic Health System, Inc.
    Inventors: David E. Lewis, Michael D. Caldwell
  • Publication number: 20120034290
    Abstract: The present invention relates to quaternary ammonium salts and their use as mold inhibitors. The quaternary salts can be prepared by a chloride ion-promoted reaction between a tertiary amine and an alcohol or polyol in strong acid solution. The quaternary ammonium salts can be applied to a substrate in order to impart anti-mold properties to the substrate. Preferably, the quaternary ammonium salt compounds are applied to paper substrates in an amount of about 1000 ppm. Preferably, the quaternary ammonium salts compounds are applied as mixtures of more than one quaternary ammonium salt compound. The treated substrate does not require encapsulators, binders, or retention aids.
    Type: Application
    Filed: August 29, 2007
    Publication date: February 9, 2012
    Inventors: Maurice C. Kemp, David E. Lewis
  • Publication number: 20110082194
    Abstract: A composition is provided that, when utilized in combination with warfarin, greatly improves the anticoagulant effects of warfarin in mammalian subjects. The composition is a compound having a naphthohydroquinone ring system substantially similar to the ring system of the reduced form of vitamin K1 and has the general formula: where R1 and R4 are hydrogen or acyl, R2 is a saturated or unsaturated alkyl group with up to 6 carbons, and R3 is a saturated or unsaturated alkyl group with up to 20 carbons, or R2 and R3 are part of a cyclic or polycyclic ring system.
    Type: Application
    Filed: September 30, 2010
    Publication date: April 7, 2011
    Inventors: David E. Lewis, Michael D. Caldwell
  • Publication number: 20100297207
    Abstract: The present invention relates to quaternary ammonium salts and their use as mold inhibitors. The quaternary salts can be prepared by a chloride ion-promoted reaction between a tertiary amine and an alcohol or polyol in strong acid solution. The quaternary ammonium salts can be applied to a substrate in order to impart anti-mold properties to the substrate. Preferably, the quaternary ammonium salt compounds are applied to paper substrates in an amount of about 1000 ppm. Preferably, the quaternary ammonium salts compounds are applied as mixtures of more than one quaternary ammonium salt compound. The treated substrate does not require encapsulators, binders, or retention aids.
    Type: Application
    Filed: August 29, 2007
    Publication date: November 25, 2010
    Inventors: Maurice C. Kemp, David E. Lewis
  • Patent number: 7528144
    Abstract: The present invention provides molecules and methods for fluorescent microscopy and visualization of biomolecules, such as cholesterol. In a preferred embodiment, the present invention provides a compound having the structure: wherein R1 and R2 are selected from the group consisting of H, CnH2n+1, (CH2)mNH2, (CH2)mNH—SO2—R?, and CH2CH2OCH2CH2NH2 wherein n has a value between 4 and 18, wherein m has a value between 2 and 8, and wherein R? is selected from the group consisting of CH3, C6H5, C6H4CH3, C6H4CO2H and its cyclic imide, C6H4Br, anthraquinon-2-yl, and 5-formyl-2-furyl, 2-carboxyphenyl.
    Type: Grant
    Filed: March 14, 2005
    Date of Patent: May 5, 2009
    Assignee: WiSys Technology Foundation, Inc.
    Inventors: Scott C. Hartsel, David E. Lewis
  • Publication number: 20090109352
    Abstract: A display screen mount apparatus. The apparatus includes a mounting frame positioned adjacent a vehicle ceiling. The mounting frame includes an attachment interface applying the weight of the apparatus to an external vehicle roof surface. A slide assembly includes a stationary end coupled to the mounting frame and an extensible member that is horizontally extensible from the mounting frame. A vertical support frame for supporting a display screen is pivotally coupled to the extensible member such that the support frame may be angularly rotated between a horizontal storage position and a vertical display position. A housing coupled to the support frame provides a housing recess for receiving the screen. The apparatus further includes an L-shaped fulcrum lever having a user-actuated arm and a spring-actuated arm. The user-actuated arm is coupled in parallel with the support frame. A pneumatic spring is coupled between and applies an expansive force between the slide assembly and the spring-actuated arm.
    Type: Application
    Filed: October 29, 2007
    Publication date: April 30, 2009
    Inventors: BRIAN E. LEWIS, David E. Lewis, Robert Fairchild
  • Patent number: 7323436
    Abstract: An adduct that has an acidic solution of sparingly-soluble Group IIA complexes (“AGIIS”) and at least one additive. The AGIIS can be prepared by mixing a mineral acid (such as sulfuric acid), and a Group IIA hydroxide (such as calcium hydroxide) or a Group IIA salt of a dibasic acid (such as calcium sulfate), or a mixture of the two Group IIA compounds, followed by removing the solid formed. The additives can be an alcohol, an organic acid or a surface active agent. The composition has various uses, including cleaning, food production, decontamination, bioremediation, agricultural application, medical application, and detoxification of substances.
    Type: Grant
    Filed: August 19, 2002
    Date of Patent: January 29, 2008
    Assignee: Mionix Corporation
    Inventors: Maurice Clarence Kemp, Robert B. Lalum, Zhong Wei Xie, Michael A. Cunha, Robert H. Carpenter, Zhang Shu, Yao Yu, David E. Lewis
  • Patent number: 6902753
    Abstract: An acidic solution of sparingly-soluble Group IIA complexes (“AGIIS”), its preparation and its uses. The AGIIS can be prepared by mixing a mineral acid (such as sulfuric acid), and a Group IIA hydroxide (such as calcium hydroxide) or a Group IIA salt of a dibasic acid (such as calcium sulfate), or a mixture of the two Group IIA compounds, followed by removing the solid formed. The various uses include cleaning, food production, decontamination, bioremediation, agricultural application, medical application, and detoxification of substances.
    Type: Grant
    Filed: February 9, 2000
    Date of Patent: June 7, 2005
    Assignee: Mionix Corporation
    Inventors: Maurice Clarence Kemp, Robert B. Lalum, Zhong Wei Xie, Michael A. Cunha, Robert H. Carpenter, Zhang Shu, Yao Yu, David E. Lewis
  • Patent number: 6881424
    Abstract: A highly acidic metalated organic acid composition and its preparation. The acidic composition can be prepared by mixing a monovalent or polyvalent cation and an organic acid in the presence of a strong oxyacid, wherein the resultant acidic composition is less corrosive to a ferrous metal than a solution of a mineral acid having the same acidic pH value as that of the acidic composition, and where in the acid composition is more biocidal than a mixture of the organic acid and a metal salt of the organic acid which mixture has the same acid normality value as that of the acidic composition. The acidic composition can be prepared by mixing at least one regenerating acid, at least one metal base, and at least one organic acid, wherein the amount of the regenerating acid is in excess of the equivalent amount of the metal base.
    Type: Grant
    Filed: September 5, 2000
    Date of Patent: April 19, 2005
    Assignee: Mionix Corporation
    Inventors: Maurice Clarence Kemp, Robert Blaine Lalum, David E. Lewis, Robert H. Carpenter
  • Patent number: 6808730
    Abstract: The use of a highly acidic metalated organic acid composition (“HAMO”) as a food additive. The HAMO is used to reduce biological contaminants, and thus preserve, a nutriment. The HAMO is being absorbed in, or adsorbed on, a nutriment material to give a prepared nutriment.
    Type: Grant
    Filed: February 18, 2003
    Date of Patent: October 26, 2004
    Assignee: Mionix Corporation
    Inventors: Maurice Clarence Kemp, Robert Blaine Lalum, David E. Lewis
  • Patent number: 6670170
    Abstract: A cell perifusion chamber structure capable of continuously monitoring processes during polymerase chain reaction includes a cell chamber body having a support surface with an aperture defined through the support surface, and wall structure extending upwardly from the support surface to define an interior. The wall structure includes passages therein. A gasket is disposed on the support surface so as not to cover the aperture. A first transparent cover is disposed on the gasket so as to cover the aperture. A water bath body is provided and has a first portion and a second portion extending from the first portion. The first portion defines a second support surface. The second portion is received in the interior of the cell chamber body and is in interference fit arrangement with the wall structure. The water bath body has an interior support surface with an aperture therethrough. The aperture extends through the first and second portions.
    Type: Grant
    Filed: May 15, 2000
    Date of Patent: December 30, 2003
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: Stephen L. Gaffin, Michael Koratich, David E. Lewis, Bruce Smith
  • Publication number: 20030161926
    Abstract: The use of a highly acidic metalated organic acid composition (“HAMO”) as a food additive. The HAMO is used to reduce biological contaminants, and thus preserve, a nutriment. The HAMO is being absorbed in, or adsorbed on, a nutriment material to give a prepared nutriment.
    Type: Application
    Filed: February 18, 2003
    Publication date: August 28, 2003
    Applicant: Mionix Corporation
    Inventors: Maurice Clarence Kemp, Robert Blaine Lalum, David E. Lewis
  • Patent number: 6572908
    Abstract: The use of a highly acidic metalated organic acid composition (“HAMO”) as a food additive. The HAMO is used to reduce biological contaminants, and thus preserve, a nutriment. The HAMO is being absorbed in, or adsorbed on, a nutriment material to give a prepared nutriment.
    Type: Grant
    Filed: January 19, 2001
    Date of Patent: June 3, 2003
    Assignee: Mionix Corporation
    Inventors: Maurice Clarence Kemp, Robert Blaine Lalum, David E. Lewis, Robert H. Carpenter
  • Patent number: 6548881
    Abstract: Method for stepping identification and bond pad crater jeopardy identification in integrated circuits and apparatus which performs the method, A unique device, a polysilicon meander, is formed under each bond pad in the integrated circuit device. Connected to the meander is circuitry for determining the electrical, and hence mechanical, integrity of the meander. Failure of the meander by reason of microcrack formation in the several layers under the meander is detected by the high resistance of the meander. The circuitry will also resolve any potential mismatch between the actual mask revision of the integrated circuit and the corresponding revision of the test program.
    Type: Grant
    Filed: July 25, 2000
    Date of Patent: April 15, 2003
    Assignee: Advanced Micro Devices, Inc.
    Inventors: Richard C. Blish, Pramod D. Patel, David E. Lewis, Colin D. Hatchard
  • Publication number: 20030050199
    Abstract: An adduct that has an acidic solution of sparingly-soluble Group IIA complexes (“AGIIS”) and at least one additive. The AGIIS can be prepared by mixing a mineral acid (such as sulfuric acid), and a Group IIA hydroxide (such as calcium hydroxide) or a Group IIA salt of a dibasic acid (such as calcium sulfate), or a mixture of the two Group IIA compounds, followed by removing the solid formed. The additives can be an alcohol, an organic acid or a surface active agent. The composition has various uses, including cleaning, food production, decontamination, bioremediation, agricultural application, medical application, and detoxification of substances.
    Type: Application
    Filed: August 19, 2002
    Publication date: March 13, 2003
    Applicant: Morningstar Diagnostics, Inc.
    Inventors: Maurice Clarence Kemp, Robert B. Lalum, Zhong Wei Xie, Michael A. Cunha, Robert H. Carpenter, Zhang Shu, Yao Yu, David E. Lewis
  • Publication number: 20020197365
    Abstract: A highly acidic metalated mixture of inorganic acids (“HAMMIA”). The acidic mixture or composition can be isolated from a mixture prepared by mixing a salt of phosphoric acid, and a preformed, or in-situ generated, solution or suspension of an acidic sparingly-soluble Group IIA complex (“AGIIS”), wherein the solution or suspension of AGIIS is in an amount sufficient to render the acidic pH of the composition to be less than about 2. An adduct which contains the acidic composition discussed above and an additive. Also a method to reduce biological contaminants in a nutriment material using the acidic composition or the adduct.
    Type: Application
    Filed: June 4, 2001
    Publication date: December 26, 2002
    Inventors: Maurice Clarence Kemp, Robert Blaine Lalum, David E. Lewis
  • Publication number: 20020198385
    Abstract: A class of predominantly hydrophilic 1,8-naphthalimide dyes. The dye contains at least two 1,8-naphthalimide ring systems, joined by a spacer moiety. Each of the 1,8-naphthalimide ring system has a ring nitrogen atom and bears, at the 4 position, an amino nitrogen atom, carrying a hydrogen. The remaining unsatisfied valences, if present, of the ring nitrogen atoms or the amino nitrogen atoms, or all, are occupied by one or more alkyl substituents. Each of the 1,8-naphthalimide ring system is free of an azo substituent and is also free of a nucleofuge. Upon activation by an activating agent in an environment independent of the presence or absence of oxygen, these compounds generate activated species. The activated species can cause structural changes in lipid and any associated proteins and polypeptides, extra- or intra-cellular or transmembrane, leading to polymerization and crosslinking.
    Type: Application
    Filed: June 21, 2002
    Publication date: December 26, 2002
    Applicant: MICROBIOMED CORP.
    Inventors: David E. Lewis, Ronald E. Utecht, Millard M. Judy, J. Lester Matthews
  • Patent number: 6436891
    Abstract: An adduct that has an acidic solution of sparingly-soluble Group IIA complexes (“AGIIS”) and at least one additive. The AGIIS can be prepared by mixing a mineral acid (such as sulfuric acid), and a Group IIA hydroxide (such as calcium hydroxide) or a Group IIA salt of a dibasic acid (such as calcium sulfate), or a mixture of the two Group IIA compounds, followed by removing the solid formed. The additives can be an alcohol, an organic acid or a surface active agent. The composition has various uses, including cleaning, food production, decontamination, bioremediation, agricultural application, medical application, and detoxification of substances.
    Type: Grant
    Filed: February 9, 2000
    Date of Patent: August 20, 2002
    Assignee: Mionix Corporation
    Inventors: Maurice Clarence Kemp, Robert B. Lalum, Zhong Wei Xie, Michael A. Cunha, Robert H. Carpenter, Zhang Shu, Yao Yu, David E. Lewis