Abstract: A method is provided for preparing a tissue implant for implantation. The method includes harvesting a tissue material from a human or an animal donor, treating the tissue material with water or a hypotonic solution to lyse native cells of the tissue material, treating the tissue material in a nuclease-containing solution which includes an antimicrobial, treating the tissue material with an alkaline alcohol solution, treating the tissue material with a chlorine dioxide treatment solution, and sterilizing the tissue material.

Abstract: Vessel wound closure systems and method for sealing a puncture wound in a target vessel, such as those puncture wounds that occur from prior interventional procedures. A sealing member is deployed intravascularly into the target vessel, and an anchor member is deployed extravascularly of the target vessel. The sealing member and the anchor member are connected by a suture that may be drawn to tighten the sealing member and the anchor member relative to one another in order to effect the seal of the puncture wound. After tightening, the suture is secured to maintain the sealing member and the anchor member relative to one another in order to maintain the seal. Preferably, the anchor member, the suture and the sealing member are comprised of biocompatible, bioresorbable materials that are absorbed into the body after the sealing of the puncture wound has been achieved.

Abstract: Methods of making dough pieces that can be baked to form baked bread articles having a reduced number of voids in the crumb are provided.

Abstract: Methods of making dough pieces that can be baked to form baked bread articles having a reduced number of voids in the crumb are provided.

Abstract: Implantable devices (e.g., stent) having a protein patterning or bioactive patterning for accelerated healing and method of forming and using the same are provided.

Abstract: Implantable devices (e.g., stent) having a protein patterning or bioactive patterning for accelerated healing and method of forming and using the same are provided.

Abstract: A clutch mechanism for use with a carrier of a linear drive device includes a housing, a first gear, and a first clutch arrangement. The first gear coupled to the housing and has gear teeth to engage a threaded shaft of a linear drive device. Rotation of the shaft causes the housing to move along the shaft in a first mode of operation. The first clutch arrangement prevents substantial rotation of the first gear. The first gear permits rotation of the first gear with respect to the housing. The housing can be manually moved along a length of the shaft, in a second mode of operation, by exerting a force on the housing. The rotational force applied to the first gear through the interaction of the threaded shaft and the gear teeth exceeds the first threshold.

Abstract: The present invention is a telescopic drive device of a device for holding a surgical instrument. The telescopic drive device includes a support; a first telescopic stage carried by the support; a first telescopic stage carried by the support, the first telescopic stage being able to perform a first motion with respect to the support; a second telescopic stage, which is able to perform a second motion with respect to the first telescopic stage; and a drive system, which is operable to drive the first and second motions. The first telescopic element performs the first motion and the second telescopic element simultaneously performs the second motion. The telescopic drive is operable to support a further device and to move the further device such that the movement is centered around a point or wherein each of the telescopic elements is arcuate.

Abstract: Implantable devices (e.g., stent) having a protein patterning or bioactive patterning for accelerated healing and method of forming and using the same are provided.

Abstract: Implantable devices (e.g., stent) having a protein patterning or bioactive patterning for accelerated healing and method of forming and using the same are provided.

Abstract: A media network is described. In an exemplary embodiment, the media network includes a plurality of media elements such as, for example, a plurality of display elements.

Abstract: The present invention relates to a method of polishing an implantable medical device. The method may include positioning an implantable medical device on a support. At least a portion of a surface of the implantable medical device may include a polymer. A fluid may be contacted with at least a portion of the surface of the positioned implantable medical device. In an embodiment, the fluid may be capable of dissolving at least a portion of the polymer at or near the surface of the implantable medical device. The method may further include allowing the fluid to modify at least a portion of the surface of the positioned medical device. A majority of the contacted fluid may be removed from the surface of the implantable medical device. In certain embodiments, the modified portion of the surface may be substantially less thrombogenetic and substantially more mechanically stable than an unmodified surface.

Abstract: Various embodiments of stents with a polymeric body with radiopaque metallic particles incorporated in the stent body.

Abstract: Disclosed is a stent comprising a bioabsorbable polymeric scaffolding; and a plurality of depots in at least a portion of the scaffolding, wherein the plurality of depots comprise a bioabsorbable material, wherein the degradation rate of all or substantially all of the bioabsorbable polymer of the scaffolding is faster than the degradation rate of all or substantially all of the bioabsorbable material of the depots.

Abstract: A medical safety device is provided and includes a needle hub having a needle supported thereon; and a safety shield operatively mounted on the needle hub. The safety shield includes a pair of spaced legs and a foot member. Each proximal segment includes a camming surface. The safety shield further includes a trigger supported on the foot member. The trigger includes a camming member and is movable to move the camming member into engagement with the camming surfaces of the proximal segments to effect movement of the legs from a first position in which the distal ends of the distal segments shield a distal end of the needle to a second position in which the distal end of the needle is at least partially exposed. The trigger is removably secured to the foot member.

Abstract: Methods and devices relating to polymer blend implantable medical devices are disclosed.

Abstract: A medical device such as a stent with a catheter, delivery balloon and an infrared energy source is disclosed. The infrared energy source heats the delivery balloon, and/or the stent to a temperature above body temperature, thereby increasing the flexibility of the stent such that formation of cracks in the stent upon its expansion is reduced or eliminated. Either the delivery balloon, and/or the stent may include an infrared energy absorbing material.

Abstract: A medical device such as a stent with a catheter, delivery balloon and a resistive heater for the balloon is disclosed. The resistive heater may be on top of, inside of the balloon or within the materials that make up the balloon. Resistive heaters may include metal foils, metallic printed circuits, and powdered conducting and semi-conducting metals.

Abstract: The current invention relates to an implantable medical device made of semi-crystalline poly(ester amide) (PEA) polymer.