Abstract: A solid-state hydrophone may include a piezoelectric rod positioned between at least two electrodes. The piezoelectric rod may be disposed within a metallic housing to shield the piezoelectric rod and its connections from acoustic and electromagnetic waves. The piezoelectric rod and the electrodes may be potted in the mechanical housing using a potting material that may be positioned adjacent to the piezoelectric rod. At least a layer of the potting material may be positioned between the piezoelectric rod and the metallic housing to physically separate the piezoelectric rod from the metallic housing.

Abstract: A Reflux Rinsing apparatus for purifying crystals using solvent vapor through dynamic equilibrium recrystallization. A pressure vessel contains a liquefied gas solvent, impure crystalline starting material initially, and a purified crystalline mass at the conclusion of the purifying process. A mechanism is provided for providing pressure to contents of the pressure vessel and for heating the lower portion thereof. A timer is also connected to the mechanism, the timer being set to heat the pressure vessel to drive vapors and reflux rinsing to remove impurities at the surface of an impure crystalline mass, to reclaim the solvent, leaving purified crystals and impurities in the pressure vessel, and to open the pressure vessel to remove the purified crystals from the vessel walls and bottom surface and to remove the impurities from the vessel. The angle of a crystal bed in the apparatus can be adjusted.

Abstract: The disclosure relates to methods for inhibiting the stability of a biofilm comprising contacting the biofilm with an effective amount of an agent that interferes with the binding of a polyamine to DNA in the biofilm. Also provided herein are methods for treating a biofilm in a subject comprising administering to the subject infected with a biofilm an effective amount of an agent that interferes with the binding of a polyamine to the DNA in the biofilm. Further described herein are methods for treating a biofilm in a patient suffering from systemic lupus erythematosus (SLE) and/or cystic fibrosis (CF) comprising administering an effective amount of an agent that interferes with the conversion of B-DNA to Z-DNA in the biofilm or its local environment.

Abstract: Methods of breaking down a biofilm or inhibiting, preventing or treating a microbial infection that produces a biofilm are disclosed, which involves administration of a polypeptide that has one or more modified HMG-box 1 domains to a subject suffering from the infection or having the biofilm. By competing with microbial proteins that bind to DNA scaffold in the biofilm, these polypeptides destabilize the biofilm leading to destruction and removal of the biofilm by the immune system.

Abstract: A Reflux Rinsing method for purifying crystals using solvent vapor through dynamic equilibrium recrystallization. Feed material having tetrahydrocannabinol (THC) is inserted into a reaction vessel having walls, and upper portion, and a lower portion with a bottom surface. The feed material is exposed to a hydrocarbon liquid in the reaction vessel in a quantity sufficient to keep liquid present in equilibrium with gas in the reaction vessel through the recrystallization process, forming a raw extract having THC. The walls and bottom surface of the reaction vessel are coated with raw extract. The reaction vessel is heated and then the heating is discontinued. Vapor/thin-film DER is promoted in the reaction vessel for a predetermined length of time with no solvent reflux, resulting in formation of purified crystals of THC acid under pressure. The hydrocarbon solvent is reclaimed from the reaction vessel, leaving the purified crystals and impurities.

Abstract: A Reflux Rinsing apparatus for purifying crystals using solvent vapor through dynamic equilibrium recrystallization. A pressure vessel contains a liquefied gas solvent, impure crystalline starting material initially, and a purified crystalline mass at the conclusion of the purifying process. A mechanism is provided for providing pressure to contents of the pressure vessel and for heating the lower portion thereof. A timer is also connected to the mechanism, the timer being set to heat the pressure vessel to drive vapors and reflux rinsing to remove impurities at the surface of an impure crystalline mass, to reclaim the solvent, leaving purified crystals and impurities in the pressure vessel, and to open the pressure vessel to remove the purified crystals from the vessel walls and bottom surface and to remove the impurities from the vessel. The angle of a crystal bed in the apparatus can be adjusted.

Abstract: A Reflux Rinsing method for purifying crystals using solvent vapor through dynamic equilibrium recrystallization. Feed material having tetrahydrocannabinol (THC) is inserted into a reaction vessel having walls, and upper portion, and a lower portion with a bottom surface. The feed material is exposed to a hydrocarbon liquid in the reaction vessel in a quantity sufficient to keep liquid present in equilibrium with gas in the reaction vessel through the recrystallization process, forming a raw extract having THC. The walls and bottom surface of the reaction vessel are coated with raw extract. The reaction vessel is heated and then the heating is discontinued. Vapor/thin-film DER is promoted in the reaction vessel for a predetermined length of time with no solvent reflux, resulting in formation of purified crystals of THC acid under pressure. The hydrocarbon solvent is reclaimed from the reaction vessel, leaving the purified crystals and impurities.

Abstract: A wireline system includes a control system, a downhole tool, and a wireline cable coupling the downhole tool and the control system. The wireline cable includes a plurality of conductors, which includes a core conductor and a concentric conductor disposed around the core conductor, wherein two of the plurality of conductors form a conductor pair, and wherein each of the plurality of conductors is configured to transmit power, data, or both, between the control system and the downhole tool. The wireline cable further includes one or more insulative layers, wherein at least one insulative layer is disposed between any two conductors.

Abstract: A current fed power supply circuit, a method for producing DC voltages from a current source, and a power delivery system are provided herein. One embodiment of a current fed power supply circuit includes: (1) input terminals, (2) an energy storage device having a first end coupled to the input terminals, (3) power switching circuitry coupled to a second end of the energy storage device and including a transformer having a primary winding and a plurality of secondary windings, and (4) multiple output terminals that are each uniquely coupled to one of the plurality of secondary windings, wherein the power switching circuitry converts a current received at the input terminals to a plurality of regulated voltages at the multiple output terminals.

Abstract: Binding agents able to disrupt bacterial biofilms of diverse origin are described, including monoclonal antibodies secreted by human B lymphocytes. Methods to prevent formation of or to dissolve biofilms with these binding agents are also described. Immunogens for eliciting antibodies to disrupt biofilms are also described.

Abstract: A method for evaluating deep vein thrombosis (DVT) caused by a blood clot formed in a deep vein of a patient is provided. The method includes receiving, at a computing device in communication with an ultrasound imaging device, an ultrasound signal representative of an ultrasound echo reflected from the blood clot, wherein the ultrasound echo is associated with an ultrasound pulse transmitted by the ultrasound imaging device; determining, by the computing device, an acuteness of the blood clot based on a strength of the ultrasound signal; and outputting, to a display in communication with the computing device, a graphical indication of the determined acuteness. In some embodiments, the method further includes transmitting, by use of the ultrasound imaging device, the ultrasound pulse into the deep vein where the blood clot is positioned.

Abstract: Binding agents able to disrupt bacterial biofilms of diverse origin are described, including monoclonal antibodies suitable for administration to a selected species, and antibody mimics including aptamer nucleic acids. Methods to prevent formation of or to dissolve biofilms with these binding agents are also described. Immunogens for eliciting antibodies to disrupt biofilms are also described.

Abstract: A method for purifying crystals in a glass or metal container. A hydrocarbon is introduced into feed material containing tetrahydrocannabinol (THC). The feed material and hydrocarbon is placed in a glass or metal container. The hydrocarbon is then removed within a few minutes after introduction, leaving at least some hydrocarbon in the feed material. Pressure is allowed to build within the container in an oven or in a jacketed vessel for 2-3 weeks. During this time, THC acid crystals precipitate out and fall to the bottom of the container. The contents of the container are poured into a Buchner funnel and a vacuum is applied thereto in order to pull terpenes into a beaker. The terpenes are placed into an oven in order to purge off any remaining solvent. The funnel is then scraped to acquire THC acid crystals.

Abstract: A Reflux Rinsing apparatus for purifying crystals using solvent vapor through dynamic equilibrium recrystallization. A pressure vessel contains a liquefied gas solvent, impure crystalline starting material initially, and a purified crystalline mass at the conclusion of the purifying process. A mechanism is provided for providing pressure to contents of the pressure vessel and for heating the lower portion thereof. A timer is also connected to the mechanism, the timer being set to heat the pressure vessel to drive vapors and reflux rinsing to remove impurities at the surface of an impure crystalline mass, to reclaim the solvent, leaving purified crystals and impurities in the pressure vessel, and to open the pressure vessel to remove the purified crystals from the vessel walls and bottom surface and to remove the impurities from the vessel. The angle of a crystal bed in the apparatus can be adjusted.

Abstract: A Reflux Rinsing method for purifying crystals using solvent vapor through dynamic equilibrium recrystallization. Feed material having tetrahydrocannabinol (THC) is inserted into a reaction vessel having walls, and upper portion, and a lower portion with a bottom surface. The feed material is exposed to a hydrocarbon liquid in the reaction vessel in a quantity sufficient to keep liquid present in equilibrium with gas in the reaction vessel through the recrystallization process, forming a raw extract having THC. The walls and bottom surface of the reaction vessel are coated with raw extract. The reaction vessel is heated and then the heating is discontinued. Vapor/thin-film DER is promoted in the reaction vessel for a predetermined length of time with no solvent reflux, resulting in formation of purified crystals of THC acid under pressure. The hydrocarbon solvent is reclaimed from the reaction vessel, leaving the purified crystals and impurities.

Abstract: Provided herein are microspheres containing an antimicrobial agent encapsulated within a glycosidic polymer and use thereof, especially to inhibit the growth of carie-causing organism.

Abstract: Various embodiments include a fiber optic nuclear magnetic resonance (NMR) sensor tool device and systems. One such tool includes a permanent magnet that generates a static magnetic field. A transmit antenna in the tool can operate to transmit a time-varying signal that is orthogonal to the static magnetic field. A fiber optic sensor element includes a coating that phase modulates a light signal traveling in the fiber when the coating is exposed to a varying field (e.g., a received, reflected magnetic field corresponding to the transmitted time-varying signal). The coating may be one of a magnetostrictive coating or a piezoelectric coating. Additional apparatus, systems, and methods are disclosed.

Abstract: A current fed power supply circuit, a method for producing DC voltages from a current source, and a power delivery system are provided herein. One embodiment of a current fed power supply circuit includes: (1) input terminals, (2) an energy storage device having a first end coupled to the input terminals, (3) power switching circuitry coupled to a second end of the energy storage device and including a transformer having a primary winding and a plurality of secondary windings, and (4) multiple output terminals that are each uniquely coupled to one of the plurality of secondary windings, wherein the power switching circuitry converts a current received at the input terminals to a plurality of regulated voltages at the multiple output terminals.

Abstract: A wireline system includes a control system, a downhole tool, and a wireline cable coupling the downhole tool and the control system. The wireline cable includes a plurality of conductors, which includes a core conductor and a concentric conductor disposed around the core conductor, wherein two of the plurality of conductors form a conductor pair, and wherein each of the plurality of conductors is configured to transmit power, data, or both, between the control system and the downhole tool. The wireline cable further includes one or more insulative layers, wherein at least one insulative layer is disposed between any two conductors.

Abstract: A method for purifying crystals in a glass or metal container. A hydrocarbon is introduced into feed material containing tetrahydrocannabinol (THC). The feed material and hydrocarbon is placed in a glass or metal container. The hydrocarbon is then removed within a few minutes after introduction, leaving at least some hydrocarbon in the feed material. Pressure is allowed to build within the container in an oven or in a jacketed vessel for 2-3 weeks. During this time, THC acid crystals precipitate out and fall to the bottom of the container. The contents of the container are poured into a Buchner funnel and a vacuum is applied thereto in order to pull terpenes into a beaker. The terpenes are placed into an oven in order to purge off any remaining solvent. The funnel is then scraped to acquire THC acid crystals.