Patents by Inventor David Gordon Lindsay

David Gordon Lindsay has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 3950517
    Abstract: A physiologically acceptable insulin derivative has the terminal amino group of the B chain (B.sub.1, phenylalanine) protected by an acyl group or other blocking group containing up to 7 carbon atoms and the amino group of the A chain (A.sub.1, glycine) is either free or protected by means of an acyl or other blocking group containing no more than four carbon atoms and preferably no more than three atoms other than hydrogen. Pharmaceutical preparations may be prepared containing an effective amount of such an insulin derivative together with a physiologically acceptable diluent. An insulin derivative of reduced antigenicity is obtainable from porcine or bovine insulin by reacting the insulin with an acylating agent or other blocking reagent to acylate or otherwise block the amino group of the B.sub.1 amino acid and optionally block the A.sub.1 and/or B.sub.29 amino acid, followed by purification of the derivative by various methods.
    Type: Grant
    Filed: December 6, 1974
    Date of Patent: April 13, 1976
    Assignee: National Research Development Corporation
    Inventors: David Gordon Lindsay, Sydney Shall