Abstract: The present invention relates to a press-heating gas grafting hydrophobization apparatus, and a hot water-resistant paper and an oil-absorbing paper manufactured using the press-heating gas grafting hydrophobization apparatus. In the press-heating gas grafting hydrophobization apparatus according to the present invention, since a non-air-permeable dryer belt is provided surrounding and pressing a drying roller to prevent dissipation from a base material of a fatty acid chloride vaporized by the drying roller, the press-heating gas grafting hydrophobization apparatus has an advantage of improving efficiency of a gas grafting reaction. Therefore, by using the press-heating gas grafting hydrophobization apparatus according to the present invention, the reaction amount of fatty acid chloride per unit area can be remarkably improved.

Abstract: This compressed air generation system (12) for an automotive vehicle (V) comprises: —a turbocompressor (4) feeding an internal combustion engine (2) of the automotive vehicle (V) with compressed air, —an air compressor (8), —at least one compressed air tank (10) connected to an outlet pipe (82) of the air compressor (8), the air compressor (8) comprising an inlet pipe (80) fed with compressed air from the turbocompressor (4). The compressed air generation system (12) comprises a pressure regulator (14) placed downstream the turbocompressor (4) and upstream the air compressor (8) and which limits the pressure (P8) of the compressed air fed from the turbocompressor (4) to the air compressor (8) to a first threshold (T1).

Abstract: Described herein are novel compounds, compositions and methods for treatment of diseases including cancer using such compounds, compositions, and methods.

Abstract: The present invention relates to a composite cellulose material, comprising: —a layer of a cellulose material, —a starch-based reinforcement grid which is positioned on at least one surface of the layer of cellulose material, the reinforcement grid comprising a plurality of meshes which are delimited by grid wires, the composite cellulose material having a relief in three dimensions comprising folds in the positioning zones of the reinforcement grid, and relief bumps on either side of the plane of the grid which are delimited by the folds.

Abstract: The present invention relates to a press-heating gas grafting hydrophobization apparatus, and a hot water-resistant paper and an oil-absorbing paper manufactured using the press-heating gas grafting hydrophobization apparatus. In the press-heating gas grafting hydrophobization apparatus according to the present invention, since a non-air-permeable dryer belt is provided surrounding and pressing a drying roller to prevent dissipation from a base material of a fatty acid chloride vaporized by the drying roller, the press-heating gas grafting hydrophobization apparatus has an advantage of improving efficiency of a gas grafting reaction. Therefore, by using the press-heating gas grafting hydrophobization apparatus according to the present invention, the reaction amount of fatty acid chloride per unit area can be remarkably improved.

Abstract: This compressed air generation system (12) for an automotive vehicle (V) comprises: —a turbocompressor (4) feeding an internal combustion engine (2) of the automotive vehicle (V) with compressed air, —an air compressor (8), —at least one compressed air tank (10) connected to an outlet pipe (82) of the air compressor (8), the air compressor (8) comprising an inlet pipe (80) fed with compressed air from the turbocompressor (4). The compressed air generation system (12) comprises a pressure regulator (14) placed downstream the turbocompressor (4) and upstream the air compressor (8) and which limits the pressure (P8) of the compressed air fed from the turbocompressor (4) to the air compressor (8) to a first threshold (T1).

Abstract: Disclosed are a sorbent produced by recycling waste paper, which is an eco-friendly recycling paper resource, to adsorb and remove a marine spilled oil and other types of oil and a method of producing the same. The oil sorbent is produced by hydrophobizing a biomass material such as waste paper using a gas-grafting method. Compared to the oil sorbent of the prior art formed of synthetic resin, it is possible to provide excellent oil adsorption selectivity, a high oil adsorption rate, and a low water absorption rate. Therefore, an incineration process for processing the waste oil sorbent after use is easy advantageously. The oil sorbent generates less harmful substances during combustion because the eco-friendly material is used. Since a biomass material is hydrophobized using vegetable fatty acids, decomposition is performed fast within a short time in a landfill process, and there is no risk of environmental pollution.

Abstract: The invention relates to a process for manufacturing a laminated material (S) comprising a fibrillated cellulose layer, characterized in that it comprises the following steps: (a) depositing a suspension (1) of fibrillated cellulose on a filtration membrane (2) and draining the suspension through that membrane so as to form a wet layer of fibrillated cellulose (A) having a dryness, that is to say a ratio between the mass of dry matter and the total mass of the fibrillated cellulose layer, of between 5% and 18%; (b) transferring the wet layer (A) under pressure to an at least partially hydrophilic surface of a substrate (B), so as to form the laminated material (S); (c) drying the laminated material. The invention also relates to a device for implementing the process.

Abstract: A method for fixing a first surface to a second surface. The method comprises depositing a first layer of nanocellulose on the first surface; bringing the first layer of nanocellulose into contact with the second surface or with a second layer of nanocellulose deposited on the second surface; and fixing the first layer of nanocellulose to the second surface, the second surface containing cellulose, or to the second layer of nanocellulose by a step of ultrasonic welding, which results in a first zone comprising the first layer of nanocellulose, where the first surface is fixed to the second surface, and a second zone around the first zone, where the first surface is not fixed to the second surface.

Abstract: The invention relates to a machine for chromatogenous grafting treatment of a scrolling substrate (S) having a hydroxylated face (Fh), comprising: an application device (3) of a grafting reagent on the hydroxylated face (Fh) of the substrate, a heating roller (4) for the development of the grafting reaction on the hydroxylated face (Fh) of the substrate, said roller (4) being provided with a bar-end system (5a, 5b) for applying a face of the substrate (S) against said heating roller (4), an extraction device (6) of the hydrochloric acid produced during the grafting reaction, an application device (7) of an air knife on the treated face of the substrate for eliminating the residual grafting reagent. The invention also relates to a chromatogenous grafting process used in said machine.

Abstract: The instant invention provides compounds of Formula (I) which are JAK inhibitors, and as such are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer. The present invention provides novel compounds which are inhibitors of JAKs. The invention also provides a method for the treatment and prevention of JAK-mediated diseases and disorders using the novel compounds, as well as pharmaceutical compositions containing the compounds.

Abstract: The instant invention provides compounds of formula I which are JAK inhibitors, and as such are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.

Abstract: The invention relates to a process for manufacturing a laminated material (S) comprising a fibrillated cellulose layer, characterized in that it comprises the following steps: (a) depositing a suspension (1) of fibrillated cellulose on a filtration membrane (2) and draining the suspension through that membrane so as to form a wet layer of fibrillated cellulose (A) having a dryness, that is to say a ratio between the mass of dry matter and the total mass of the fibrillated cellulose layer, of between 5% and 18%; (b) transferring the wet layer (A) under pressure to an at least partially hydrophilic surface of a substrate (B), so as to form the laminated material (S); (c) drying the laminated material. The invention also relates to a device for implementing the process.

Abstract: Provided are compounds of Formula I, a JAK inhibitor, and use thereof for the treatment of JAK-mediated diseases by the application.

Abstract: The instant invention provides compounds of Formula (I) which are JAK inhibitors, and as such are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.

Abstract: The present invention provides a compound of Formula (I) or the pharmaceutically acceptable salts, esters, and prodrugs thereof, which are ERK2 inhibitors. The invention also provides a pharmaceutical composition comprising an effective amount of at least one compound of Formula (I) and a pharmaceutically acceptable carrier. The invention also provides a pharmaceutical composition comprising an effective amount of at least one compound of Formula (I) and an effective amount of at least one other pharmaceutically active ingredient (such as, for example, a chemotherapeutic agent), and a pharmaceutically acceptable carrier.

Abstract: Using the sympathetic printed-matter according to the present invention, a hidden content can be visualized just by wetting. Therefore, it is possible to remove necessities of the sympathetic ink and a special material such as reagent or equipment for visualizing hidden contents. In addition, since the hidden contents disappear by removing water from the sympathetic printed-matter, the sympathetic printed-matter can be used repeatedly. Using the reading confirmation portion, whether or not the sympathetic printed-matter has been read by any other person can be easily determined. In the sympathetic printing method according to the present invention, a hydrophobic substrate can be formed using an existing gas grafting facility, and an ester hydrolase composition and the reading confirmation portion can be formed using an existing printing method. Therefore, a large amount of sympathetic printed-matters can be produced inexpensively and efficiently.

Abstract: The present invention provides a compound of Formula (I) or the pharmaceutically acceptable salts, esters, and prodrugs thereof, which are ERK2 inhibitors. The invention also provides a pharmaceutical composition comprising an effective amount of at least one compound of Formula (I) and a pharmaceutically acceptable carrier. The invention also provides a pharmaceutical composition comprising an effective amount of at least one compound of Formula (I) and an effective amount of at least one other pharmaceutically active ingredient (such as, for example, a chemotherapeutic agent), and a pharmaceutically acceptable carrier.

Abstract: The instant invention provides compounds of Formula (I) which are JAK inhibitors, and as such are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer. The present invention provides novel compounds which are inhibitors of JAKs. The invention also provides a method for the treatment and prevention of JAK-mediated diseases and disorders using the novel compounds, as well as pharmaceutical compositions containing the compounds.

Abstract: Compounds of formula I are provided, which are JAK inhibitors and are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.