Patents by Inventor David H. Kinder

David H. Kinder has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds for prevention of diabetic retinopathy
    Publication number: 20030099724
    Abstract: Compounds for the prevention and retardation of diabetic retinopathy, and the loss of visual acuity and blindness that can be caused by diabetic retinopathy. The compounds may include a magnesium salt, a vasodilator, aminoguanidine, an anti-inflammatory agent, and an antioxidant.
    Type: Application
    Filed: November 16, 2001
    Publication date: May 29, 2003
    Inventors: Oliver E. Turner, John J. Abbott, David H. Kinder
  • Cytotoxic boronic acid peptide analogs
    Patent number: 5159060
    Abstract: A method is provided for inhibiting growth of cancer cells comprising contacting said cells with an effective growth-inhibiting amount of a compound of the formula (II): ##STR1## or a physiologically acceptable salt thereof, wherein A.sup.1 and A.sup.2 are individually L-amino acid residue selected from the group consisting of Ala, Pro, Gly, Glu, Leu, Lys, Phe, Ser, Vl, Ile, Arg, Tyr, Thr, Asp, Asn and Gly; R.sup.1 is C.sub.1 -C.sub.6 (alkyl) which is unsubstituted or is substituted with an aromatic substituent or one or more in-chain bivalent groups selected from the group consisting of --O--, --CO--, --S--, --NH--, --CONH--, CH.dbd.CH--, and --SO.sub.2 --; Y.sup.1 and Y.sup.2 are each H, or taken together form a moiety derived from a dihydroxy compound, and R.sup.1 is H or an N-terminal protecting group.
    Type: Grant
    Filed: January 21, 1992
    Date of Patent: October 27, 1992
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: David H. Kinder, Matthew M. Ames
  • Cytotoxic boronic acid peptide analogs
    Patent number: 5106948
    Abstract: A method is provided for inhibiting growth of cancer cells comprising contacting said cells with an effective growth-inhibiting amount of a compound of the formula (II): ##STR1## or a physiologically acceptable salt thereof, wherein A.sup.1 and A.sup.2 are individually L-amino acid residues selected from the group consisting of Ala, Pro, Gly, Glu, Leu, Lys, Phe, Ser, Val, Ile, Arg, Tyr, Thr, Asp, Asn and Gly; R.sup.1 is C.sub.1 -C.sub.6 (alkyl) which is unsubstituted or is substituted with an aromatic substituent or one or more in-chain bivalent groups selected from the group consisting of --O--, --CO--, --S--, --NH--, --CONH--, CH.dbd.CH--, and --SO.sub.2 --; Y.sup.1 and Y.sup.2 are each H, or taken together from a moiety derived from a dihydroxy compound, and R.sup.1 is H or an N-terminal protecting group.
    Type: Grant
    Filed: August 28, 1990
    Date of Patent: April 21, 1992
    Assignee: Mao Foundation for Medical Education and Research
    Inventors: David H. Kinder, Matthew M. Ames
  • Boron analogs of amino acid/peptide protease inhibitors
    Patent number: 4963655
    Abstract: A method of inhibiting protease activity, growth, and colony formation in mammalian tumor cells by boronic acid analogs of amino acids, dipeptides and tripeptides. A method of coupling a boronic acid analog of an amino acid to other N-protected amino acids or N-protected dipeptides and compositions formed from the coupled products.
    Type: Grant
    Filed: May 27, 1988
    Date of Patent: October 16, 1990
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: David H. Kinder, Matthew M. Ames