Patents by Inventor David H. Lee
David H. Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240112589Abstract: Systems and methods for controlling behavior change in a user. Systems can include a behavior change model management system and a behavior change facilitation system included as part of a behavior change platform. Methods can include selecting a behavior change model based on a behavior-specific behavior change phenotype of a user and applying the behavior change model to control behavior change in the user.Type: ApplicationFiled: October 5, 2023Publication date: April 4, 2024Inventors: Eugene H. Lee, David McKinnon Lawrence, Khanderao Kand
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Publication number: 20240099256Abstract: The present disclosure provides alfalfa plants exhibiting broad spectrum resistance to Race 1, Race 2, and Race 5 anthracnose. Such plants may comprise novel introgressed genomic regions associated with disease resistance from Race 1, Race 2, and Race 5 anthracnose. In certain aspects, compositions, including novel polymorphic markers and methods for producing, breeding, identifying, and selecting plants or germplasm with a disease resistance phenotype are provided. Also provided are alfalfa varieties designated as C0416C4164 and H0415C4114. Provided by the invention are the seeds, plants and derivatives of alfalfa varieties C0416C4164 and H0415C4114. Also provided by the invention are tissue cultures of alfalfa varieties C0416C4164 and H0415C4114, and the plants regenerated therefrom. Still further provided by the invention are methods for producing alfalfa plants by crossing alfalfa variety C0416C4164 or H0415C4114 with itself or another alfalfa variety and plants produced by such methods.Type: ApplicationFiled: October 4, 2023Publication date: March 28, 2024Inventors: Charles A. Rodgers, Mark H. McCaslin, David D. Witte, Julie Chiu-Lee Ho, John Nicholas Cameron
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Publication number: 20240098969Abstract: Systems, methods and apparatus are provided for an array of vertically stacked memory cells having horizontally oriented access devices and storage nodes formed in tiers. And, more particularly, to multiple, alternating silicon germanium (SiGe) and single crystalline silicon (Si) in different thicknesses to form tiers in which to form the horizontal access devices in vertical three-dimensional (3D) memory. The horizontally oriented access devices can have a first source/drain regions and a second source drain regions separated by single crystalline silicon (Si) channel regions. The single crystalline silicon (Si) channel regions can include a dielectric material to provide support structure to the single crystalline channel regions when forming the horizontal access devices in vertical three-dimensional (3D) memory. Horizontally oriented access lines can connect to gate structures opposing the channel regions. Vertical digit lines coupled to the first source/drain regions.Type: ApplicationFiled: September 15, 2022Publication date: March 21, 2024Inventors: David K. Hwang, Yoshitaka Nakamura, Scott E. Sills, Si-Woo Lee, Yuanzhi Ma, Glen H. Walters
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Publication number: 20240098970Abstract: Systems, methods and apparatus are provided for an array of vertically stacked memory cells having horizontally oriented access devices and storage nodes. The horizontally oriented access devices having a first source/drain regions and a second source drain regions separated by silicon (Si) channel regions. A digit line having a global digit line (GDL) contact is formed in a trench adjacent to the first source/drain regions. In one example, the digit line is electrically isolated from a neighboring digit line at the bottom of the trench. In another example, the digit line is formed continuously along a bottom surface of trench to form shared digit lines between horizontal access devices, in two separate arrays, on opposing second vertical surfaces. The memory cells have horizontally oriented storage nodes coupled to the second source/drain regions and vertical digit lines coupled to the first source/drain regions.Type: ApplicationFiled: September 16, 2022Publication date: March 21, 2024Inventors: Scott E. Sills, Si-Woo Lee, David K. Hwang, Yoshitaka Nakamura, Yuanzhi Ma, Glen H. Walters
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Patent number: 9405884Abstract: The present invention relates to methods for analyzing protein samples, e.g., monoclonal antibodies, via the SITRS technique, as well as methods and systems that facilitate the processing of data generated by the SITRS technique.Type: GrantFiled: December 20, 2011Date of Patent: August 2, 2016Assignee: AbbVie Inc.Inventors: David H. Lee, Anton V. Manuilov
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Patent number: 9170262Abstract: Methods of qualitatively and/or quantitatively detecting the presence of mutations, modifications or impurities in a protein sample are provided. The methods utilize isotopically labeled variants of amino acids incorporated into proteins prior to protein digest to enable comparisons of two protein samples in bottom-up liquid chromatography.Type: GrantFiled: June 16, 2011Date of Patent: October 27, 2015Assignee: AbbVie, Inc.Inventors: Anton V. Manuilov, David H. Lee
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Patent number: 8684343Abstract: A composite fabrication vent assembly for connection to an inflatable bladder, the combination of a vent assembly and an inflatable bladder, and a method of mechanically connecting a vent assembly and a bladder. The vent assembly comprises a body member having a first clamping surface, a clamping member having a second clamping surface, and a carriage member interconnecting the body member and the clamping member, with the first and second clamping surfaces in opposing relationship. With the open end of an inflatable bladder inserted between the opposed clamping surfaces, the carriage member is adapted to translate the body member and clamping member toward one another to form an airtight seal with the inflatable bladder. A controlled source of pressurized gas, connected to a gas inlet of the vent assembly, can then inflate and deflate the bladder in a controlled manner through one or more passageways in the vent assembly.Type: GrantFiled: January 6, 2012Date of Patent: April 1, 2014Assignee: Rubbercraft Corporation of California LtdInventors: Alan D. Hiken, David H. Lee, Robert L. Harshberger, Leo H. Phan, Rufino Santos
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Publication number: 20130175749Abstract: A composite fabrication vent assembly for connection to an inflatable bladder, the combination of a vent assembly and an inflatable bladder, and a method of mechanically connecting a vent assembly and a bladder. The vent assembly comprises a body member having a first clamping surface, a clamping member having a second clamping surface, and a carriage member interconnecting the body member and the clamping member, with the first and second clamping surfaces in opposing relationship. With the open end of an inflatable bladder inserted between the opposed clamping surfaces, the carriage member is adapted to translate the body member and clamping member toward one another to form an airtight seal with the inflatable bladder. A controlled source of pressurized gas, connected to a gas inlet of the vent assembly, can then inflate and deflate the bladder in a controlled manner through one or more passageways in the vent assembly.Type: ApplicationFiled: January 6, 2012Publication date: July 11, 2013Inventors: ALAN D. HIKEN, David H. Lee, Robert L. Harshberger, Leo H. Phan, Rufino Santos
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Patent number: 8338230Abstract: A system and method are provided in which a first chip in a stacked multi-chip module configuration is affixed via one or more adhesion layers to a first portion of a partitioned interposer unit. Planar partitions of the interposer are physically bonded via multiple solder “bumps,” which possess high tensile strength but low resistance to horizontal shear force or torque. A second chip is affixed via one or more adhesion layers to the second portion of the partitioned interposer. The chips may thus be separated by horizontally and oppositely shearing or twisting the first and second portions of the partitioned interposer away from one another.Type: GrantFiled: September 27, 2011Date of Patent: December 25, 2012Assignee: BAE Systems Information and Electronic Systems Integration Inc.Inventors: John A. Hughes, Thomas E. Love, Eugene Lemoine, David H. Lee, Christopher Ebel
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Publication number: 20120245857Abstract: The present invention relates to methods for analyzing protein samples, e.g., monoclonal antibodies, via the SITRS technique, as well as methods and systems that facilitate the processing of data generated by the SITRS technique.Type: ApplicationFiled: December 20, 2011Publication date: September 27, 2012Applicant: Abbott LaboratoriesInventors: David H. Lee, Anton V. Manuilov
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Publication number: 20110312010Abstract: Methods of qualitatively and/or quantitatively detecting the presence of mutations, modifications or impurities in a protein sample are provided. The methods utilize isotopically labeled variants of amino acids incorporated into proteins prior to protein digest to enable comparisons of two protein samples in bottom-up liquid chromatography.Type: ApplicationFiled: June 16, 2011Publication date: December 22, 2011Applicant: ABBOTT LABORATORIESInventors: Anton V. MANUILOV, David H. LEE
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Patent number: 8067829Abstract: A system and method are provided in which a first chip in a stacked multi-chip module configuration is affixed via one or more adhesion layers to a first portion of a partitioned interposer unit. Planar partitions of the interposer are physically bonded via multiple solder “bumps,” which possess high tensile strength but low resistance to horizontal shear force or torque. A second chip is affixed via one or more adhesion layers to the second portion of the partitioned interposer. The chips may thus be separated by horizontally and oppositely shearing or twisting the first and second portions of the partitioned interposer away from one another.Type: GrantFiled: April 29, 2009Date of Patent: November 29, 2011Assignee: BAE Systems Information and Electronic Systems Integration Inc.Inventors: John A. Hughes, Thomas E. Love, Eugene Lemoine, David H. Lee, Christopher Ebel
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Publication number: 20100276794Abstract: A system and method are provided in which a first chip in a stacked multi-chip module configuration is affixed via one or more adhesion layers to a first portion of a partitioned interposer unit. Planar partitions of the interposer are physically bonded via multiple solder “bumps,” which possess high tensile strength but low resistance to horizontal shear force or torque. A second chip is affixed via one or more adhesion layers to the second portion of the partitioned interposer. The chips may thus be separated by horizontally and oppositely shearing or twisting the first and second portions of the partitioned interposer away from one another.Type: ApplicationFiled: April 29, 2009Publication date: November 4, 2010Applicant: BAE SYSTEMS Information and Electronic Systems Integration Inc.Inventors: John A. Hughes, Thomas E. Love, Eugene Lemoine, Christopher Ebel, David H. Lee
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Patent number: 6825217Abstract: Compositions and methods are provided for treating neuropathic pain or neuropathic dysfunction that include the administration of an effective amount of a defined carbinol or a pharmaceutically acceptable salt or prodrug thereof.Type: GrantFiled: October 16, 2002Date of Patent: November 30, 2004Assignee: Endo Pharmaceuticals, Inc.Inventors: Richard Carliss, David A. H. Lee
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Publication number: 20030162811Abstract: Compositions and methods are provided for treating neuropathic pain or neuropathic dysfunction that include the administration of an effective amount of a defined carbinol or a pharmaceutically acceptable salt or prodrug thereof.Type: ApplicationFiled: October 16, 2002Publication date: August 28, 2003Inventors: Richard Carliss, David A.H. Lee
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Publication number: 20030125300Abstract: Thiolester-activated amino acids; thiolester-activated nucleotides; polypeptide-oligonucleotide fusions comprising a polypeptide of interest and a thiolester-activated nucleotide; methods of producing the thiolester-activated nucleotides of the present invention; methods of producing polypeptide-oligonucleotide fusions of the present invention; and methods in which the polypeptide-oligonucleotide fusions are used, such as methods of delivering nucleic acid molecules into cells and cell lines.Type: ApplicationFiled: October 15, 2002Publication date: July 3, 2003Applicant: Whitehead Institute for Biomedical ResearchInventor: David H. Lee
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Patent number: 4350713Abstract: Sponge cake is formed by the utilization of a continuous process involving an initial batter formation and subsequent microwave baking. Cake-forming components and carbon dioxide are continuously mixed to form a gas-infused batter. Microwave energy expands and cooks the batter to form the sponge cake. Additional drying may be effected to any desired moisture level.Type: GrantFiled: March 16, 1981Date of Patent: September 21, 1982Assignee: The Griffith Laboratories, LimitedInventors: David V. Dyson, David H. Lees, Michael A. F. Fenn, Kenneth S. Darley
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Patent number: D357027Type: GrantFiled: November 15, 1993Date of Patent: April 4, 1995Inventors: David H. Lee, Lawrence Moss