Patents by Inventor David H. Swenson

David H. Swenson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hyperstabilizing antisense nucleic acid binding agents
    Patent number: 5786138
    Abstract: Attaching certain ligands to antisense probes will hyperstabilize sense-antisense duplexes. Such a hyperstabilized duplex is resistant to melting of the strands from one another, to unwinding of the strands, and to the action of nucleases. Applications include antiretroviral action, anti-reverse-transcriptase action, antiviral action, antiparasitical action, antibacterial action, antifungal action, anticancer action, anti-oncogene action, and other applications where it is desired to inhibit gene expression at the genomic or messenger RNA level. The preferred ligands are certain minor-groove-binding agents, exemplified by CC-1065 and synthetic CC-1065 analogs.
    Type: Grant
    Filed: August 11, 1994
    Date of Patent: July 28, 1998
    Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventor: David H. Swenson
  • Hyperstabilizing antisense nucleic acid binding agents
    Patent number: RE38169
    Abstract: Attaching certain ligands to antisense probes will hyperstabilize sense-antisense duplexes. Such a hyperstabilized duplex is resistant to melting of the strands from one another, to unwinding of the strands, and to the action of nucleases. Applications include antiretroviral action, antireverse-transcriptase action, antiviral action, antiparasitical action, antibacterial action, antifungal action, anticancer action, anti-oncogene action, and other applications where it is desired to inhibit gene expression at the genomic or messenger RNA level. The preferred ligands are certain minor-groove-binding agents, exemplified by CC-1065 and synthetic CC-1065 analogs.
    Type: Grant
    Filed: July 26, 2000
    Date of Patent: July 1, 2003
    Assignee: Board of Supervisors of Louisana State University and Agricultural and Mechanical College
    Inventor: David H. Swenson