Abstract: A golf club head having a flexible channel to improve the performance of the club head, and a channel tuning system to reduce undesirable club head characteristics introduced, or heightened, via the flexible channel. The channel tuning system includes a sole engaging channel tuning element in contact with the sole and the channel. The club head may include an aerodynamic configuration, as well as a body tuning system.

Abstract: Disclosed herein is a golf club head comprising at least one crown opening and at least one crown insert attached to the body and covering the at least one crown opening. The golf club head further comprises at least one sole opening and at least one sole insert attached to the body and covering the at least one sole opening. The golf club head additionally includes at least one weight member configured to clamp first and second ledges at selected locations along a sliding weight track. The golf club head also comprise a coefficient of restitution (COR) feature located on the sole of the golf club head. The at least one crown insert is formed from a composite material having a density between 1 g/cc and 2 g/cc. The at least one sole insert is formed from a composite material having a density between 1 g/cc and 2 g/cc.

Abstract: Disclosed is a mobile event streaming system that receives customer application lifecycle and user events including a message, event source and a destination then processes data for consumption by one or more customers, generating a secure data stream and sending the processed data over the generated data stream. An example system for receiving, processing, and delivering customer application lifecycle and user engagement data includes a server system having at least one processor, memory and a network interface where the memory stores program instructions for receiving, storing, processing and transmitting messages via the network interface. The mobile event streaming system may be a distributed content delivery service wherein the content delivered via the service is processed. Processing the data comprises the addition of metadata, one or more identifiers such as user, and event identifiers including predictions of future user engagement to enable real-time data consumption by customers.

Abstract: The present disclosure is directed to a power tool including a motor housing and an electric motor situated within the motor housing. The electric motor is configured to provide rotational energy to rotate an output device of the power tool about an output axis. The power tool also includes a cover configured to cover at least a portion of a surface of the motor housing that faces the output device. The power tool further includes a first lighting device located within the cover and a second lighting device located within the cover. The first lighting device and the second lighting device are located around the output axis and are separated from each other by at least 130 degrees about the output axis. The power tool also includes first power wires configured to provide power to the first lighting device from a power source of the power tool.

Abstract: A robotic system may comprise a first robotic arm operatively coupleable to a first tool. The first tool has a first working end. The system may also comprise an image capture device, a display, and a processor. The processor may be configured to cause an image of a work site, which was captured by the image capture device from a perspective of an image reference frame, to be displayed on the display. The image of the work site includes an image of the first working end of the first tool. The processor may also determine a position of the first working end of the first tool in the image of the work site and render a tool information overlay at the position of the first working end of the first tool in the image of the work site. The tool information overlay visually indicates state information for the first tool. The processor may also change the tool information overlay while the first tool is in a first operational state by changing a brightness of the tool information overlay.

Abstract: Methods and systems for monitoring microbial activity and microbial communication in an environment are disclosed. Exemplary methods include measuring a high impedance voltage between a reference electrode and one or more measurement electrodes to monitor microbial activity. Microorganisms form a biofilm that attaches to at least one of the one or more inert measurement electrodes and that allows for measuring the microbial activity, characterizing the environment, and/or monitoring microbial communication in the environment.

Abstract: A strain gauge includes a resistor formed of a doped silicon material, a conductive shield, and an isolation element disposed between the resistor and the conductive shield. The isolation element electrically isolates the resistor from the conductive shield.

Abstract: The invention relates to compounds of formula I wherein R1, R2 and - - - - - are as defined herein, pharmaceutical compositions comprising the compounds and methods of treating COVID-19 in a patient by administering therapeutically effective amounts of the compounds and methods of inhibiting or preventing replication of SARS-CoV-2 with the compounds.

Abstract: Provided herein are methods of determining treatment outcome in a subject having a disease, the method including evaluating RNA expression level of a B cell related gene to determine a B cell gene signature; evaluating RNA expression level of a CD8+ T cell related gene to determine a CD8+ T cell gene signature; analyzing the B cell gene signature and the CD8+ T cell gene signature (B8T gene signature); and determining treatment outcome in a subject based on the B8T gene signature.

Abstract: Embodiments of the present disclosure relate scheduling maintenance services for a special-purpose vehicle. In an exemplary embodiment, a user device comprises a user interface, a processor, and memory comprising instructions that when executed by the processor cause the processor to output, to the user interface, a plurality of service method icons. The plurality of service methods comprise a first service method icon corresponding to a service being performed on the special-purpose vehicle at a first location and a second service method icon corresponding to the service being performed on the special-purpose vehicle at a second location. The first location and the second location are different locations. The memory also comprises instructions that when executed by the processor cause the processor to receive, via the user interface, a selection of a service method icon of the plurality of service method icons and send, to a scheduling server, a signal corresponding to the selected service method icon.

Abstract: A tilted structured illumination pattern for use in an optical system is generated, wherein the tilted structured illumination pattern is not symmetrical about a center point of a back pupil of the system, and wherein the tilted structured illumination pattern is based on exactly two wave vectors and defines spatial frequencies along an optical axis of an objective of the system. The tilted structured illumination pattern is directed to be incident on a sample, such that one or more fluorophores of the sample are excited by the structured illumination pattern. A phase of the tilted structured illumination pattern is varied. A set of images of fluorescence emission emitted by the sample is captured, wherein each image of the set of images corresponds to a respective phase of the tilted structured illumination pattern and to a respective axial imaging plane. Combined image data is generated based on the set of images.

Abstract: In an x-ray source, an isolation circuit can isolate bias voltage at a cathode from a bias voltage at an alternating current source (AC source). The isolation circuit can transfer alternating current from the AC source to the cathode. The isolation circuit can be made repeatedly with minimal variation or failed parts, can be light, and can be small. The isolation circuit can include planar transformer(s). Each planar transformer can include a primary trace on a primary circuit board and a secondary trace on a secondary circuit board. The primary trace and the secondary trace can each include a spiral shape. The primary trace can be located in close proximity to the secondary trace such that alternating electrical current through the primary trace will induce alternating electrical current through the secondary trace.

Abstract: Disclosed is a mobile event streaming system that receives customer application lifecycle and user events including a message, event source and a destination then processes data for consumption by one or more customers, generating a secure data stream and sending the processed data over the generated data stream. An example system for receiving, processing, and delivering customer application lifecycle and user engagement data includes a server system having at least one processor, memory and a network interface where the memory stores program instructions for receiving, storing, processing and transmitting messages via the network interface. The mobile event streaming system may be a distributed content delivery service wherein the content delivered via the service is processed. Processing the data comprises the addition of metadata, one or more identifiers such as user, and event identifiers including predictions of future user engagement to enable real-time data consumption by customers.

Abstract: The present disclosure relates to methods for preparing biological samples for in situ analysis of one or more analytes wherein the biological sample has been previously affixed to a substrate, which in some cases may not be compatible with in situ analysis, for example, due to the absence of positional markers and/or fiducial markers and/or a region suitable for in situ signal detection on the substrate. In some aspects, a hydrophobic adapter having positional markers and/or fiducial markers is applied to the substrate to which a biological sample has been affixed, thus enabling in situ sample processing and analysis of the biological sample. The hydrophobic adhesive label or adapter can be used for automated microscope alignment and sample preparation.

Abstract: A microbial sensor, system, and method that can be used to determine a chemical environment and/or substrate concentrations in anaerobic or aerobic environments, such as soils, sediments and ground waters, are disclosed. An exemplary system uses one or more (e.g., inert) measurement electrodes and a reference electrode. The reference electrode can include an electrode exposed to atmospheric oxygen (e.g., a cathode) or an electrode exposed to stable anaerobic or aerobic conditions. The exemplary microbial sensor system measures open-circuit voltage to characterize the chemical (oxidizing or reducing) environment and/or recovery voltage to measure substrate concentrations in the subsurface.

Abstract: Disclosed is a mobile event streaming system that receives customer application lifecycle and user events including a message, event source and a destination then processes data for consumption by one or more customers, generating a secure data stream and sending the processed data over the generated data stream. An example system for receiving, processing, and delivering customer application lifecycle and user engagement data includes a server system having at least one processor, memory and a network interface where the memory stores program instructions for receiving, storing, processing and transmitting messages via the network interface. The mobile event streaming system may be a distributed content delivery service wherein the content delivered via the service is processed. Processing the data comprises the addition of metadata, one or more identifiers such as user, and event identifiers including predictions of future user engagement to enable real-time data consumption by customers.

Abstract: It would be advantageous to reduce weight and size of high voltage power supplies, to increase frequency of pulses of high voltage, and to improve control of magnitude of high voltage. The embodiments of high voltage power supplies described herein can solve these problems. The high voltage power supply can be used with an x-ray tube. The high voltage power supply can comprise an array of planar transformers each defining a stage with an AC input and a DC output. Each stage can comprise a pair of flat, coil windings adjacent one another and including a primary winding electrically-coupled to the AC input and configured to induce a current in a secondary winding. At least two stages can be electrically-coupled together in series with the DC output of one stage electrically-coupled to an input of the other stage such that a voltage is amplified across the stages.

Abstract: A system for performing vascular hemostasis comprises a balloon insertable into a tissue track so as to be disposed outside a vessel above an opening formed in the vessel. A hemostasis layer is removably disposed on at least a portion of an outer surface of the balloon. A balloon tube is fluidly coupled to the balloon and configured to selectively inflate or deflate the balloon. The balloon is inflatable above the opening such that the hemostasis layer is disposed on the outer surface of the vessel and closes the opening. The hemostasis layer is separable from the balloon so as to remain disposed on the outer surface of the vessel when the balloon is removed from the tissue track, and continues to close the opening after removal of the balloon.

Abstract: The subject disclosure encompasses solutions for matching customer information with customer reviews. A process of the disclosed technology includes steps for aggregating customer data associated with a customer, retrieving a plurality of customer reviews, wherein each of the customer reviews describe customer satisfaction with a service provided by a corresponding service provider, extracting review metadata for each of the plurality of customer reviews, and matching the customer with at least one of the customer reviews based on the customer data and the extracted review metadata. Systems and machine-readable media are also provided.

Abstract: A microbial sensor, system and method that can be used to determine the biochemical conditions of waters, saturated sediments, unsaturated soils, rhizosphere and other environments is disclosed. The flexibility of the microbial sensor design allows for the monitoring of surfaces (skin, ventilation conduits, etc.). An electrochemical microbial sensor system is composed of an indicator electrode(s) and a reference electrode. The reference electrode employs a hydrogen permeable membrane. The electrochemical system is interfaced into a signal/communication module allowing the manual or automated collection of data from field deployments and laboratory investigations. The data is transmitted using various communication technologies including Bluetooth™, cellular, satellite and radio telemetry to cloud-based data management systems. The stored data may be downloaded by users using open-source dashboard and visualization software to image the various environments and/or surfaces investigated.