Patents by Inventor David Hosfield

David Hosfield has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modulators of resistant androgen receptor
    Patent number: 11739069
    Abstract: The present invention provides compounds useful as modulators, agonists or antagonists of androgen receptor (AR), compositions thereof, and methods of making and using the same.
    Type: Grant
    Filed: October 21, 2019
    Date of Patent: August 29, 2023
    Assignee: Memorial Sloan-Kettering Cancer Center
    Inventors: Minna D. Balbas, Michael J. Evans, Charles L. Sawyers, Yang Shen, David Hosfield, Geoffrey L. Greene
  • MODULATORS OF RESISTANT ANDROGEN RECEPTOR
    Publication number: 20200172504
    Abstract: The present invention provides compounds useful as modulators, agonists or antagonists of androgen receptor (AR), compositions thereof, and methods of making and using the same.
    Type: Application
    Filed: October 21, 2019
    Publication date: June 4, 2020
    Inventors: Minna D. Balbas, Michael J. Evans, Charles L. Sawyers, Yang Shen, David Hosfield, Geoffrey L. Greene
  • Modulators of resistant androgen receptor
    Patent number: 10450294
    Abstract: The present invention provides compounds useful as modulators, agonists or antagonists of androgen receptor (AR), compositions thereof, and methods of making and using the same.
    Type: Grant
    Filed: May 12, 2017
    Date of Patent: October 22, 2019
    Assignee: Memorial Sloan-Kettering Cancer Center
    Inventors: Minna D. Balbas, Michael J. Evans, Charles L. Sawyers, Yang Shen, David Hosfield, Geoffrey L. Greene
  • MODULATORS OF RESISTANT ANDROGEN RECEPTOR
    Publication number: 20170320849
    Abstract: The present invention provides compounds useful as modulators, agonists or antagonists of androgen receptor (AR), compositions thereof, and methods of making and using the same.
    Type: Application
    Filed: May 12, 2017
    Publication date: November 9, 2017
    Inventors: Minna D. Balbas, Michael J. Evans, Charles L. Sawyers, Yang Shen, David Hosfield, Geoffrey L. Greene
  • Modulators of resistant androgen receptor
    Patent number: 9650359
    Abstract: The present invention provides compounds useful as modulators, agonists or antagonists of androgen receptor (AR), compositions thereof, and methods of making and using the same.
    Type: Grant
    Filed: May 18, 2016
    Date of Patent: May 16, 2017
    Assignee: Memorial Sloan-Kettering Cancer Center
    Inventors: Minna D. Balbas, Michael J. Evans, Charles L. Sawyers, Yang Shen, David Hosfield, Geoffrey L. Greene
  • MODULATORS OF RESISTANT ANDROGEN RECEPTOR
    Publication number: 20160257666
    Abstract: The present invention provides compounds useful as modulators, agonists or antagonists of androgen receptor (AR), compositions thereof, and methods of making and using the same.
    Type: Application
    Filed: May 18, 2016
    Publication date: September 8, 2016
    Inventors: Minna D. Balbas, Michael J. Evans, Charles L. Sawyers, Yang Shen, David Hosfield, Geoffrey L. Greene
  • Modulators of resistant androgen receptor
    Patent number: 9365542
    Abstract: The present invention provides compounds useful as modulators, agonists or antagonists of androgen receptor (AR), compositions thereof, and methods of making and using the same. Compounds of the present invention, and pharmaceutically acceptable compositions thereof, are useful in medicine, and particularly for treating any of a variety of diseases, disorders or conditions.
    Type: Grant
    Filed: October 25, 2013
    Date of Patent: June 14, 2016
    Assignee: Memorial Sloan-Kettering Cancer Center
    Inventors: Minna D. Balbas, Michael J. Evans, Charles L. Sawyers, Yang Shen, David Hosfield, Geoffrey L. Greene
  • MODULATORS OF RESISTANT ANDROGEN RECEPTOR
    Publication number: 20150274693
    Abstract: The present invention provides compounds useful as modulators, agonists or antagonists of androgen receptor (AR), compositions thereof, and methods of making and using the same. Compounds of the present invention, and pharmaceutically acceptable compositions thereof, are useful in medicine, and particularly for treating any of a variety of diseases, disorders or conditions.
    Type: Application
    Filed: October 25, 2013
    Publication date: October 1, 2015
    Inventors: Minna D. Balbas, Michael J. Evans, Charles L. Sawyers, Yang Shen, David Hosfield, Geoffrey L. Greene
  • Crystalline composition of farsenyl pyrophosphate synthase (IspA)
    Patent number: 7563610
    Abstract: Provided are crystals relating to Farsenyl Pvrophosphate Synthase (IspA) from E. coli and its various uses.
    Type: Grant
    Filed: August 28, 2003
    Date of Patent: July 21, 2009
    Assignee: Takeda San Diego, Inc.
    Inventors: Alexei Brooun, Douglas R. Dougan, David Hosfield, Yanming Zhang
  • GLUCOKINASE ACTIVATORS
    Publication number: 20070281942
    Abstract: Compounds are provided for use with hexokinases that comprise: wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.
    Type: Application
    Filed: May 25, 2007
    Publication date: December 6, 2007
    Inventors: Sheldon Cao, Jun Feng, Stephen Gwaltney, David Hosfield, Robert Skene, Jeffrey Stafford, Mingnam Tang
  • GLUCOKINASE ACTIVATORS
    Publication number: 20070244169
    Abstract: Compounds, pharmaceutical compositions, kits and methods are provided for use with glucokinase that comprise a compound selected from the group consisting of: wherein the variables are as defined herein.
    Type: Application
    Filed: December 19, 2006
    Publication date: October 18, 2007
    Inventors: Jun Feng, Stephen Gwaltney, David Hosfield, Shigekazu Sasaki, Robert Skene, Michael Wallace
  • GLUCOKINASE ACTIVATORS
    Publication number: 20070197532
    Abstract: Compounds, pharmaceutical compositions, kits and methods are provided for use with glucokinase that comprise a compound selected from the group consisting of: wherein the variables are as defined herein.
    Type: Application
    Filed: November 17, 2006
    Publication date: August 23, 2007
    Inventors: Sheldon Cao, Jun Feng, Yasuhiro Imaeda, Stephen Gwaltney, David Hosfield, Nobuyuki Takakura, Mingnam Tang
  • Kinase inhibitors
    Publication number: 20060084650
    Abstract: Compounds, pharmaceutical compositions and kits are provided for use with kinases that comprise a compound selected from the group consisting of: wherein the variables are as defined herein.
    Type: Application
    Filed: October 14, 2005
    Publication date: April 20, 2006
    Inventors: Qing Dong, David Hosfield, Bheema Paraselli, Nicholas Scorah, Jeffrey Stafford, Michael Wallace, Zhiyuan Zhang
  • Kinase inhibitors
    Publication number: 20050250829
    Abstract: The invention relates to compounds comprising the below formula that may be used to inhibit kinases as well as compositions of matter, kits and methods comprising these compounds.
    Type: Application
    Filed: April 20, 2005
    Publication date: November 10, 2005
    Inventors: Jerome Bressi, Anthony Gangloff, David Hosfield, Andrew Jennings, Bheema Paraselli, Jeffrey Stafford