Abstract: Disclosed are compounds for inhibiting lipoamide dehydrogenase (Lpd), and methods of treating tuberculosis.

Abstract: Methods and compositions for treating leukemia are disclosed. Acylated 6-aminoindoles, acylated 6-aminopyrrolopyridines and acylated 3-aminopyrrolo[3,2-c]pyridazines of the following formula inhibit ENL/AF9 YEATS and are therefore useful for treating leukemia.

Abstract: A process for leaching laterite ores containing limonite and saprolite. Sufficient mineral acid is added to a slurry of limonite which is leached at atmospheric pressure to dissolve most of the soluble non-ferrous metals and soluble iron. After adding saprolite the slurry is further leached at a temperature above the normal boiling point and at a pressure above atmospheric pressure for a time sufficient to leach most of the contained nickel in the saprolite and to precipitate most of the iron in solution. The pressure of the slurry is then reduced, and nickel and/or cobalt is subsequently recovered from the leach solution by solvent extraction, resin-in-pulp or other ion exchange, sulfide or hydroxide precipitation, or other recovery method.

Abstract: A process for the precipitation of metallic sulfides, e.g., nickel, cobalt or zinc sulfides, from aqueous metal-ion-containing solution comprising passing hydrogen sulfide through the metal-containing solution while the solution is at a temperature of about 75.degree. C. and at a pH of about 2 to about 3 and maintaining said pH during the time of hydrogen sulfide addition by continuous addition of alkali to the solution. The precipitated metal sulfide is characterized by a relatively large particle size by a high settling rate and by ease of filterability.