Patents by Inventor David J. Bowen

David J. Bowen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20170044568
    Abstract: A pesticidal protein class exhibiting toxic activity against Coleopteran, Lepidopteran, and Hemipteran pest species is disclosed, and includes, but is not limited to, TIC5290. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding the TIC5290 pesticidal protein. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran, Coleopteran and Hemipteran infestation are provided which contain recombinant nucleic acid sequences encoding the TIC5290 pesticidal protein of the present invention. Methods for detecting the presence of the recombinant nucleic acid sequences or the protein of the present invention in a biological sample, and methods of controlling Coleopteran, Lepidopteran, and Hemipteran species pests using the TIC5290 pesticidal protein are also provided.
    Type: Application
    Filed: July 27, 2016
    Publication date: February 16, 2017
    Inventors: David J. Bowen, Catherine A. Chay, Stanislaw Flasinski, Yong Yin
  • Publication number: 20160319302
    Abstract: Insecticidal proteins exhibiting toxic activity against Coleopteran and Lepidopteran pest species are disclosed, and include, but are not limited to, TIC3668, TIC3669, TIC3670, TIC4076, TIC4078, TIC4260, TIC4346, TIC4826, TIC4861, TIC4862, TIC4863, and TIC-3668-type proteins. DNA molecules and constructs are provided which contain a polynucleotide sequence encoding one or more of the disclosed TIC3668-type proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran and Coleopteran infestation are provided which contain polynucleotide sequences encoding the insecticidal proteins of the present invention. Methods for detecting the presence of the polynucleotides or the proteins of the present invention in a biological sample, and methods of controlling Coleopteran and Lepidopteran species pests using any of the TIC3668-type insecticidal proteins are also provided.
    Type: Application
    Filed: November 18, 2015
    Publication date: November 3, 2016
    Inventors: Gregory J. Bean, David J. Bowen, Catherine A. Chay, Arlene R. Howe, Jason S. Milligan, Yong Yin
  • Publication number: 20160200778
    Abstract: The invention provides compositions comprising polynucleotide molecules encoding certain pesticidal polypeptides which exhibit plant parasitic nematode and/or insect control properties, and are particularly directed to controlling plant parasitic pest species of nematodes and insects known to infest crop plant species. Methods for controlling pests are disclosed in which the toxic proteins are provided in the diet of the targeted plant pests. The invention also provides compositions such as nucleic acids, proteins, and plant and bacterial cells, plants, and seeds containing the nucleic acid and protein compositions, as well as methods and kits for identifying, detecting, and isolating the compositions of the present invention. The invention further provides a method of producing crops from recombinant seeds which contain the polynucleotide molecules encoding the pesticidal polypeptides of the present invention.
    Type: Application
    Filed: March 30, 2016
    Publication date: July 14, 2016
    Inventors: David J. Bowen, Gregory J. Bunkers, Catherine Chay, John W. Pitkin, Timothy J. Rydel, Eric J. Sturman, Uma R. Sukuru, Brook Van Scoyoc, Stanislaw Flasinski
  • Patent number: 9328356
    Abstract: The invention provides compositions comprising polynucleotide molecules encoding certain pesticidal polypeptides which exhibit plant parasitic nematode and/or insect control properties, and are particularly directed to controlling plant parasitic pest species of nematodes and insects known to infest crop plant species. Methods for controlling pests are disclosed in which the toxic proteins are provided in the diet of the targeted plant pests. The invention also provides compositions such as nucleic acids, proteins, and plant and bacterial cells, plants, and seeds containing the nucleic acid and protein compositions, as well as methods and kits for identifying, detecting, and isolating the compositions of the present invention. The invention further provides a method of producing crops from recombinant seeds which contain the polynucleotide molecules encoding the pesticidal polypeptides of the present invention.
    Type: Grant
    Filed: February 9, 2012
    Date of Patent: May 3, 2016
    Assignee: Monsanto Technology LLC
    Inventors: David J. Bowen, Gregory J. Bunkers, Catherine Chay, John W. Pitkin, Timothy J. Rydel, Eric J. Sturman, Uma R. Sukuru, Brook Van Scoyoc, Stanislaw Flasinski
  • Publication number: 20160068858
    Abstract: The present invention discloses a genus of insect inhibitory proteins that exhibit properties directed to controlling Lepidopteran and/or Hemipteran crop pests, methods of using such proteins, nucleotide sequences encoding such proteins, methods of detecting and isolating such proteins, and their use in agricultural systems.
    Type: Application
    Filed: November 18, 2015
    Publication date: March 10, 2016
    Applicant: MONSANTO TECHNOLOGY LLC
    Inventors: David J. Bowen, Catherine Chay, Artem Evdokimov, Megan N. Schroder, Rachael N. Slightom, Uma R. Kesanapalli, Nengbing Tao, Andrew M. Wollacott
  • Publication number: 20160068857
    Abstract: The present invention discloses a genus of insect inhibitory proteins that exhibit properties directed to controlling Lepidopteran and/or Hemipteran crop pests, methods of using such proteins, nucleotide sequences encoding such proteins, methods of detecting and isolating such proteins, and their use in agricultural systems.
    Type: Application
    Filed: November 18, 2015
    Publication date: March 10, 2016
    Applicant: MONSANTO TECHNOLOGY LLC
    Inventors: David J. Bowen, Catherine Chay, Artem Evdokimov, Megan N. Schroder, Rachael N. Slightom, Uma R. Kesanapalli, Nengbing Tao, Andrew M. Wollacott
  • Patent number: 9238678
    Abstract: The present invention discloses a genus of insect inhibitory proteins that exhibit properties directed to controlling Lepidopteran and/or Hemipteran crop pests, methods of using such proteins, nucleotide sequences encoding such proteins, methods of detecting and isolating such proteins, and their use in agricultural systems.
    Type: Grant
    Filed: April 6, 2012
    Date of Patent: January 19, 2016
    Assignee: Monsanto Technology LLC
    Inventors: David J. Bowen, Catherine Chay, Artem Evdokimov, Megan N. Schroder, Rachael N. Slightom, Uma R. Kesanapalli, Nengbing Tao, Andrew M. Wollacott
  • Publication number: 20150274786
    Abstract: The invention generally relates to the field of insect inhibitory toxin proteins. A novel class of proteins exhibiting insect inhibitory activity against agriculturally relevant pests of crop plants and seeds are disclosed. Insecticidal activity is particularly effective against the Coleopteran order of insect pests. Plants, plant parts, and seed are provided containing a polynucleotide construct encoding one or more of the toxin proteins disclosed herein. The proteins are referred to herein variously as the TIC2463-related toxin protein class or family, the TIC2463-related toxin proteins, the TIC2463-related protein genus, toxin proteins related to the TIC2463 toxin protein, proteins related to TIC2463, TIC2463-related toxin polypeptides, TIC2463-related pesticidal proteins, and the like.
    Type: Application
    Filed: March 27, 2015
    Publication date: October 1, 2015
    Applicant: MONSANTO TECHNOLOGY LLC
    Inventors: David J. Bowen, Catherine A. Chay, Stanislaw Flasinski, Xiaoran Fu, Uma R. Kesanapalli, Jason S. Milligan, Rachael N. Slightom, Daqi Tu, Andrew M. Wollacott, Yong Yin
  • Publication number: 20150047076
    Abstract: The present invention provides novel insecticidal proteins active against a Coleopteran and/or Hemipteran species pest, which include, but are not limited to, TIC3131, TIC3400 and TIC3407 proteins. The present invention also provides a DNA construct comprising operably linked to a heterologous promoter a polynucleotide that encodes the novel insecticidal protein or an insecticidal fragment thereof. The present invention further provides transgenic plants/plant cells/plant parts expressing the insecticidal proteins, methods for detecting the presence of the polynucleotide or the protein in a biological sample, and methods of controlling a Coleopteran and/or Hemipteran species pest using the insecticidal proteins.
    Type: Application
    Filed: August 8, 2014
    Publication date: February 12, 2015
    Applicant: Monsanto Technology LLC
    Inventors: Heather M. Anderson, David J. Bowen, Catherine A. Chay, Stanislaw Flasinski, Uma R. Kesanapalli, Jason S. Milligan, Rachael N. Slightom, Yong Yin
  • Publication number: 20130097735
    Abstract: The present invention discloses a genus of insect inhibitory proteins that exhibit properties directed to controlling Lepidopteran and/or Hemipteran crop pests, methods of using such proteins, nucleotide sequences encoding such proteins, methods of detecting and isolating such proteins, and their use in agricultural systems.
    Type: Application
    Filed: April 6, 2012
    Publication date: April 18, 2013
    Applicant: MONSANTO TECHNOLOGY LLC
    Inventors: David J. Bowen, Catherine Chay, Artem Evdokimov, Megan N. Schroder, Rachael N. Slightom, Uma Sukuru, Nengbing Tao, Andrew M. Wollacott
  • Publication number: 20120278954
    Abstract: The invention provides compositions comprising polynucleotide molecules encoding certain pesticidal polypeptides which exhibit plant parasitic nematode and/or insect control properties, and are particularly directed to controlling plant parasitic pest species of nematodes and insects known to infest crop plant species. Methods for controlling pests are disclosed in which the toxic proteins are provided in the diet of the targeted plant pests. The invention also provides compositions such as nucleic acids, proteins, and plant and bacterial cells, plants, and seeds containing the nucleic acid and protein compositions, as well as methods and kits for identifying, detecting, and isolating the compositions of the present invention. The invention further provides a method of producing crops from recombinant seeds which contain the polynucleotide molecules encoding the pesticidal polypeptides of the present invention.
    Type: Application
    Filed: February 9, 2012
    Publication date: November 1, 2012
    Inventors: David J. Bowen, Gregory J. Bunkers, Catherine Chay, John W. Pitkin, Timothy J. Rydel, Eric J. Sturman, Uma R. Sukuru, Brook Van Scoyoc
  • Patent number: 7569748
    Abstract: Proteins from the genus Photorhabdus are toxic to insects upon exposure. Photorhabdus luminescens (formerly Xenorhabdus luminescens) have been found in mammalian clinical samples and as a bacterial symbiont of entomopathogenic nematodes of genus Heterohabditis. These protein toxins can be applied to, or genetically engineered into, insect larvae food and plants for insect control.
    Type: Grant
    Filed: October 2, 2002
    Date of Patent: August 4, 2009
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Jerald C. Ensign, David J. Bowen, James Petell, Raymond Fatig, Sue Schoonover, Richard H. Ffrench-Constant, Thomas A. Rocheleau, Michael B. Blackburn, Timothy D. Hey, Donald J. Merlo, Gregory L Orr, Jean L. Roberts, James A. Strickland, Lining Guo, Todd A. Ciche, Kitisri Sukhapinda
  • Patent number: 7161062
    Abstract: Nucleotide sequences for two genes, tcdB and tccC2, from the tcd genomic region of Photorhabdus luminescens W-14 are useful in heterologous expression of orally active insect toxins.
    Type: Grant
    Filed: August 26, 2003
    Date of Patent: January 9, 2007
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Richard H. Ffrench-Constant, David J. Bowen, Thomas A. Rocheleau, Nicholas R. Waterfield
  • Publication number: 20030207806
    Abstract: Proteins from the genus Photorhabdus are toxic to insects upon exposure. Photorhabdus luminescens (formerly Xenorhabdus luminescens) have been found in mammalian clinical samples and as a bacterial symbiont of entomopathogenic nematodes of genus Heterorhabditis. These protein toxins can be applied to, or genetically engineered into, insect larvae food and plants for insect control.
    Type: Application
    Filed: October 2, 2002
    Publication date: November 6, 2003
    Inventors: Jerald C. Ensign, David J. Bowen, James Petell, Raymond Fatig, Sue Schoonover, Richard H. Ffrench-Constant, Thomas A. Rocheleau, Michael B. Blackburn, Timothy D. Hey, Donald J. Merlo, Gregory L. Orr, Jean L. Roberts, James A. Strickland, Lining Guo, Todd A. Ciche, Kitisri Sukhapinda
  • Patent number: 6639129
    Abstract: Nucleotide sequences for two genes, tcdB and tccC2, from the tcd genomic region of Photorhabdus luminescens W-14 are useful in heterologous expression of orally active insect toxins.
    Type: Grant
    Filed: March 26, 2001
    Date of Patent: October 28, 2003
    Assignees: Wisconsin Alumni Research Foundation, University of Bath
    Inventors: Richard H. ffrench-Constant, David J. Bowen, Thomas A. Rocheleau, Nicholas R. Waterfield
  • Patent number: 6528484
    Abstract: Proteins from the genus Photorhabdus are toxic to insects upon exposure. Photorhabdus luminescens (formerly Xenorhabdus luminescens) have been found in mammalian clinical samples and as a bacterial symbiont of entomopathogenic nematodes of genus Heterorhabditis. These protein toxins can be applied to, or genetically engineered into, insect larvae food and plants for insect control.
    Type: Grant
    Filed: May 5, 1997
    Date of Patent: March 4, 2003
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Jerald C. Ensign, David J. Bowen, James Petell, Raymond Fatig, Sue Schoonover, Richard H. ffrench-Constant, Thomas A. Rocheleau, Michael B. Blackburn, Timothy D. Hey, Donald J. Merlo, Gregory L. Orr, Jean L. Roberts, James A. Strickland, Lining Guo, Todd A. Ciche, Kitisri Sukhapinda
  • Publication number: 20020147148
    Abstract: Proteins from the genus Xenorhabdus are toxic to insects upon oral exposure. These protein toxins can be applied to insect larvae food and plants for insect control.
    Type: Application
    Filed: February 19, 2002
    Publication date: October 10, 2002
    Inventors: Jerald C. Ensign, David J. Bowen, Jennifer L. Tenor, Todd A. Ciche, James K. Petell, James A. Strickland, Gregory L. Orr, Raymond O. Fatig, Scott B. Bintrim, Richard H. Ffrench-Constant
  • Patent number: 6379946
    Abstract: Proteins from the genus Xenorhabdus are toxic to insects upon oral exposure. These protein toxins can be applied to insect larvae food and plants for insect control.
    Type: Grant
    Filed: February 28, 2000
    Date of Patent: April 30, 2002
    Assignee: Wisconsin Alumn Research Foundation
    Inventors: Jerald C. Ensign, David J. Bowen, Jennifer L. Tenor, James K. Petell, Gregory L. Orr, Scott B. Bintrim, Todd A. Ciche, James A. Strickland, Raymond O. Fatig, Richard H. Ffrench-Constant
  • Patent number: 6048838
    Abstract: Proteins from the genus Xenorhabdus are toxic to insects upon oral exposure. These protein toxins can be applied to insect larvae food and plants for insect control.
    Type: Grant
    Filed: May 4, 1998
    Date of Patent: April 11, 2000
    Assignee: Dow AgroSciences LLC
    Inventors: Jerald C. Ensign, David J. Bowen, Jennifer L. Tenor, Todd A. Ciche, James K. Petell, James A. Strickland, Gregory L. Orr, Raymond O. Fatig, Scott B. Bintrim, Richard H. Ffrench-Constant
  • Patent number: 4113469
    Abstract: A method is provided for refining molten metal containing an impurity which is oxidizable in preference to one or more selected constituent elements of the metal and which forms a gaseous oxide, the method comprising injecting oxygen and a diluent gas into the molten metal contained in a vessel so as to reduce the proportion of the impurity in the metal by evolution as the gaseous oxide, weighing the vessel during refining to establish a point at which the weight of the vessel contents changes significantly due to preferential oxidation of the one or more selected constituent elements, initiating at the point a reduction in the ratio of oxygen: diluent gas to as to reduce the rate of oxidation of the one or more selected constituent elements relative to the impurity and continuing injection until the proportion of the impurity is reduced to the desired level.
    Type: Grant
    Filed: May 2, 1977
    Date of Patent: September 12, 1978
    Assignee: British Steel Corporation
    Inventors: Hugh W. Grenfell, David J. Bowen, Robert Baker