Patents by Inventor David J. Bowen
David J. Bowen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20170044568Abstract: A pesticidal protein class exhibiting toxic activity against Coleopteran, Lepidopteran, and Hemipteran pest species is disclosed, and includes, but is not limited to, TIC5290. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding the TIC5290 pesticidal protein. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran, Coleopteran and Hemipteran infestation are provided which contain recombinant nucleic acid sequences encoding the TIC5290 pesticidal protein of the present invention. Methods for detecting the presence of the recombinant nucleic acid sequences or the protein of the present invention in a biological sample, and methods of controlling Coleopteran, Lepidopteran, and Hemipteran species pests using the TIC5290 pesticidal protein are also provided.Type: ApplicationFiled: July 27, 2016Publication date: February 16, 2017Inventors: David J. Bowen, Catherine A. Chay, Stanislaw Flasinski, Yong Yin
-
Publication number: 20160319302Abstract: Insecticidal proteins exhibiting toxic activity against Coleopteran and Lepidopteran pest species are disclosed, and include, but are not limited to, TIC3668, TIC3669, TIC3670, TIC4076, TIC4078, TIC4260, TIC4346, TIC4826, TIC4861, TIC4862, TIC4863, and TIC-3668-type proteins. DNA molecules and constructs are provided which contain a polynucleotide sequence encoding one or more of the disclosed TIC3668-type proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran and Coleopteran infestation are provided which contain polynucleotide sequences encoding the insecticidal proteins of the present invention. Methods for detecting the presence of the polynucleotides or the proteins of the present invention in a biological sample, and methods of controlling Coleopteran and Lepidopteran species pests using any of the TIC3668-type insecticidal proteins are also provided.Type: ApplicationFiled: November 18, 2015Publication date: November 3, 2016Inventors: Gregory J. Bean, David J. Bowen, Catherine A. Chay, Arlene R. Howe, Jason S. Milligan, Yong Yin
-
Publication number: 20160200778Abstract: The invention provides compositions comprising polynucleotide molecules encoding certain pesticidal polypeptides which exhibit plant parasitic nematode and/or insect control properties, and are particularly directed to controlling plant parasitic pest species of nematodes and insects known to infest crop plant species. Methods for controlling pests are disclosed in which the toxic proteins are provided in the diet of the targeted plant pests. The invention also provides compositions such as nucleic acids, proteins, and plant and bacterial cells, plants, and seeds containing the nucleic acid and protein compositions, as well as methods and kits for identifying, detecting, and isolating the compositions of the present invention. The invention further provides a method of producing crops from recombinant seeds which contain the polynucleotide molecules encoding the pesticidal polypeptides of the present invention.Type: ApplicationFiled: March 30, 2016Publication date: July 14, 2016Inventors: David J. Bowen, Gregory J. Bunkers, Catherine Chay, John W. Pitkin, Timothy J. Rydel, Eric J. Sturman, Uma R. Sukuru, Brook Van Scoyoc, Stanislaw Flasinski
-
Patent number: 9328356Abstract: The invention provides compositions comprising polynucleotide molecules encoding certain pesticidal polypeptides which exhibit plant parasitic nematode and/or insect control properties, and are particularly directed to controlling plant parasitic pest species of nematodes and insects known to infest crop plant species. Methods for controlling pests are disclosed in which the toxic proteins are provided in the diet of the targeted plant pests. The invention also provides compositions such as nucleic acids, proteins, and plant and bacterial cells, plants, and seeds containing the nucleic acid and protein compositions, as well as methods and kits for identifying, detecting, and isolating the compositions of the present invention. The invention further provides a method of producing crops from recombinant seeds which contain the polynucleotide molecules encoding the pesticidal polypeptides of the present invention.Type: GrantFiled: February 9, 2012Date of Patent: May 3, 2016Assignee: Monsanto Technology LLCInventors: David J. Bowen, Gregory J. Bunkers, Catherine Chay, John W. Pitkin, Timothy J. Rydel, Eric J. Sturman, Uma R. Sukuru, Brook Van Scoyoc, Stanislaw Flasinski
-
Publication number: 20160068858Abstract: The present invention discloses a genus of insect inhibitory proteins that exhibit properties directed to controlling Lepidopteran and/or Hemipteran crop pests, methods of using such proteins, nucleotide sequences encoding such proteins, methods of detecting and isolating such proteins, and their use in agricultural systems.Type: ApplicationFiled: November 18, 2015Publication date: March 10, 2016Applicant: MONSANTO TECHNOLOGY LLCInventors: David J. Bowen, Catherine Chay, Artem Evdokimov, Megan N. Schroder, Rachael N. Slightom, Uma R. Kesanapalli, Nengbing Tao, Andrew M. Wollacott
-
Publication number: 20160068857Abstract: The present invention discloses a genus of insect inhibitory proteins that exhibit properties directed to controlling Lepidopteran and/or Hemipteran crop pests, methods of using such proteins, nucleotide sequences encoding such proteins, methods of detecting and isolating such proteins, and their use in agricultural systems.Type: ApplicationFiled: November 18, 2015Publication date: March 10, 2016Applicant: MONSANTO TECHNOLOGY LLCInventors: David J. Bowen, Catherine Chay, Artem Evdokimov, Megan N. Schroder, Rachael N. Slightom, Uma R. Kesanapalli, Nengbing Tao, Andrew M. Wollacott
-
Patent number: 9238678Abstract: The present invention discloses a genus of insect inhibitory proteins that exhibit properties directed to controlling Lepidopteran and/or Hemipteran crop pests, methods of using such proteins, nucleotide sequences encoding such proteins, methods of detecting and isolating such proteins, and their use in agricultural systems.Type: GrantFiled: April 6, 2012Date of Patent: January 19, 2016Assignee: Monsanto Technology LLCInventors: David J. Bowen, Catherine Chay, Artem Evdokimov, Megan N. Schroder, Rachael N. Slightom, Uma R. Kesanapalli, Nengbing Tao, Andrew M. Wollacott
-
Publication number: 20150274786Abstract: The invention generally relates to the field of insect inhibitory toxin proteins. A novel class of proteins exhibiting insect inhibitory activity against agriculturally relevant pests of crop plants and seeds are disclosed. Insecticidal activity is particularly effective against the Coleopteran order of insect pests. Plants, plant parts, and seed are provided containing a polynucleotide construct encoding one or more of the toxin proteins disclosed herein. The proteins are referred to herein variously as the TIC2463-related toxin protein class or family, the TIC2463-related toxin proteins, the TIC2463-related protein genus, toxin proteins related to the TIC2463 toxin protein, proteins related to TIC2463, TIC2463-related toxin polypeptides, TIC2463-related pesticidal proteins, and the like.Type: ApplicationFiled: March 27, 2015Publication date: October 1, 2015Applicant: MONSANTO TECHNOLOGY LLCInventors: David J. Bowen, Catherine A. Chay, Stanislaw Flasinski, Xiaoran Fu, Uma R. Kesanapalli, Jason S. Milligan, Rachael N. Slightom, Daqi Tu, Andrew M. Wollacott, Yong Yin
-
Publication number: 20150047076Abstract: The present invention provides novel insecticidal proteins active against a Coleopteran and/or Hemipteran species pest, which include, but are not limited to, TIC3131, TIC3400 and TIC3407 proteins. The present invention also provides a DNA construct comprising operably linked to a heterologous promoter a polynucleotide that encodes the novel insecticidal protein or an insecticidal fragment thereof. The present invention further provides transgenic plants/plant cells/plant parts expressing the insecticidal proteins, methods for detecting the presence of the polynucleotide or the protein in a biological sample, and methods of controlling a Coleopteran and/or Hemipteran species pest using the insecticidal proteins.Type: ApplicationFiled: August 8, 2014Publication date: February 12, 2015Applicant: Monsanto Technology LLCInventors: Heather M. Anderson, David J. Bowen, Catherine A. Chay, Stanislaw Flasinski, Uma R. Kesanapalli, Jason S. Milligan, Rachael N. Slightom, Yong Yin
-
Publication number: 20130097735Abstract: The present invention discloses a genus of insect inhibitory proteins that exhibit properties directed to controlling Lepidopteran and/or Hemipteran crop pests, methods of using such proteins, nucleotide sequences encoding such proteins, methods of detecting and isolating such proteins, and their use in agricultural systems.Type: ApplicationFiled: April 6, 2012Publication date: April 18, 2013Applicant: MONSANTO TECHNOLOGY LLCInventors: David J. Bowen, Catherine Chay, Artem Evdokimov, Megan N. Schroder, Rachael N. Slightom, Uma Sukuru, Nengbing Tao, Andrew M. Wollacott
-
Publication number: 20120278954Abstract: The invention provides compositions comprising polynucleotide molecules encoding certain pesticidal polypeptides which exhibit plant parasitic nematode and/or insect control properties, and are particularly directed to controlling plant parasitic pest species of nematodes and insects known to infest crop plant species. Methods for controlling pests are disclosed in which the toxic proteins are provided in the diet of the targeted plant pests. The invention also provides compositions such as nucleic acids, proteins, and plant and bacterial cells, plants, and seeds containing the nucleic acid and protein compositions, as well as methods and kits for identifying, detecting, and isolating the compositions of the present invention. The invention further provides a method of producing crops from recombinant seeds which contain the polynucleotide molecules encoding the pesticidal polypeptides of the present invention.Type: ApplicationFiled: February 9, 2012Publication date: November 1, 2012Inventors: David J. Bowen, Gregory J. Bunkers, Catherine Chay, John W. Pitkin, Timothy J. Rydel, Eric J. Sturman, Uma R. Sukuru, Brook Van Scoyoc
-
Patent number: 7569748Abstract: Proteins from the genus Photorhabdus are toxic to insects upon exposure. Photorhabdus luminescens (formerly Xenorhabdus luminescens) have been found in mammalian clinical samples and as a bacterial symbiont of entomopathogenic nematodes of genus Heterohabditis. These protein toxins can be applied to, or genetically engineered into, insect larvae food and plants for insect control.Type: GrantFiled: October 2, 2002Date of Patent: August 4, 2009Assignee: Wisconsin Alumni Research FoundationInventors: Jerald C. Ensign, David J. Bowen, James Petell, Raymond Fatig, Sue Schoonover, Richard H. Ffrench-Constant, Thomas A. Rocheleau, Michael B. Blackburn, Timothy D. Hey, Donald J. Merlo, Gregory L Orr, Jean L. Roberts, James A. Strickland, Lining Guo, Todd A. Ciche, Kitisri Sukhapinda
-
Patent number: 7161062Abstract: Nucleotide sequences for two genes, tcdB and tccC2, from the tcd genomic region of Photorhabdus luminescens W-14 are useful in heterologous expression of orally active insect toxins.Type: GrantFiled: August 26, 2003Date of Patent: January 9, 2007Assignee: Wisconsin Alumni Research FoundationInventors: Richard H. Ffrench-Constant, David J. Bowen, Thomas A. Rocheleau, Nicholas R. Waterfield
-
Publication number: 20030207806Abstract: Proteins from the genus Photorhabdus are toxic to insects upon exposure. Photorhabdus luminescens (formerly Xenorhabdus luminescens) have been found in mammalian clinical samples and as a bacterial symbiont of entomopathogenic nematodes of genus Heterorhabditis. These protein toxins can be applied to, or genetically engineered into, insect larvae food and plants for insect control.Type: ApplicationFiled: October 2, 2002Publication date: November 6, 2003Inventors: Jerald C. Ensign, David J. Bowen, James Petell, Raymond Fatig, Sue Schoonover, Richard H. Ffrench-Constant, Thomas A. Rocheleau, Michael B. Blackburn, Timothy D. Hey, Donald J. Merlo, Gregory L. Orr, Jean L. Roberts, James A. Strickland, Lining Guo, Todd A. Ciche, Kitisri Sukhapinda
-
Patent number: 6639129Abstract: Nucleotide sequences for two genes, tcdB and tccC2, from the tcd genomic region of Photorhabdus luminescens W-14 are useful in heterologous expression of orally active insect toxins.Type: GrantFiled: March 26, 2001Date of Patent: October 28, 2003Assignees: Wisconsin Alumni Research Foundation, University of BathInventors: Richard H. ffrench-Constant, David J. Bowen, Thomas A. Rocheleau, Nicholas R. Waterfield
-
Patent number: 6528484Abstract: Proteins from the genus Photorhabdus are toxic to insects upon exposure. Photorhabdus luminescens (formerly Xenorhabdus luminescens) have been found in mammalian clinical samples and as a bacterial symbiont of entomopathogenic nematodes of genus Heterorhabditis. These protein toxins can be applied to, or genetically engineered into, insect larvae food and plants for insect control.Type: GrantFiled: May 5, 1997Date of Patent: March 4, 2003Assignee: Wisconsin Alumni Research FoundationInventors: Jerald C. Ensign, David J. Bowen, James Petell, Raymond Fatig, Sue Schoonover, Richard H. ffrench-Constant, Thomas A. Rocheleau, Michael B. Blackburn, Timothy D. Hey, Donald J. Merlo, Gregory L. Orr, Jean L. Roberts, James A. Strickland, Lining Guo, Todd A. Ciche, Kitisri Sukhapinda
-
Publication number: 20020147148Abstract: Proteins from the genus Xenorhabdus are toxic to insects upon oral exposure. These protein toxins can be applied to insect larvae food and plants for insect control.Type: ApplicationFiled: February 19, 2002Publication date: October 10, 2002Inventors: Jerald C. Ensign, David J. Bowen, Jennifer L. Tenor, Todd A. Ciche, James K. Petell, James A. Strickland, Gregory L. Orr, Raymond O. Fatig, Scott B. Bintrim, Richard H. Ffrench-Constant
-
Patent number: 6379946Abstract: Proteins from the genus Xenorhabdus are toxic to insects upon oral exposure. These protein toxins can be applied to insect larvae food and plants for insect control.Type: GrantFiled: February 28, 2000Date of Patent: April 30, 2002Assignee: Wisconsin Alumn Research FoundationInventors: Jerald C. Ensign, David J. Bowen, Jennifer L. Tenor, James K. Petell, Gregory L. Orr, Scott B. Bintrim, Todd A. Ciche, James A. Strickland, Raymond O. Fatig, Richard H. Ffrench-Constant
-
Patent number: 6048838Abstract: Proteins from the genus Xenorhabdus are toxic to insects upon oral exposure. These protein toxins can be applied to insect larvae food and plants for insect control.Type: GrantFiled: May 4, 1998Date of Patent: April 11, 2000Assignee: Dow AgroSciences LLCInventors: Jerald C. Ensign, David J. Bowen, Jennifer L. Tenor, Todd A. Ciche, James K. Petell, James A. Strickland, Gregory L. Orr, Raymond O. Fatig, Scott B. Bintrim, Richard H. Ffrench-Constant
-
Patent number: 4113469Abstract: A method is provided for refining molten metal containing an impurity which is oxidizable in preference to one or more selected constituent elements of the metal and which forms a gaseous oxide, the method comprising injecting oxygen and a diluent gas into the molten metal contained in a vessel so as to reduce the proportion of the impurity in the metal by evolution as the gaseous oxide, weighing the vessel during refining to establish a point at which the weight of the vessel contents changes significantly due to preferential oxidation of the one or more selected constituent elements, initiating at the point a reduction in the ratio of oxygen: diluent gas to as to reduce the rate of oxidation of the one or more selected constituent elements relative to the impurity and continuing injection until the proportion of the impurity is reduced to the desired level.Type: GrantFiled: May 2, 1977Date of Patent: September 12, 1978Assignee: British Steel CorporationInventors: Hugh W. Grenfell, David J. Bowen, Robert Baker