Patents by Inventor David J. Zaleske

David J. Zaleske has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bonding of cartilaginous matrices using isolated chondrocytes
    Publication number: 20030099620
    Abstract: Methods of bonding cartilage pieces using new cartilage matrix generated by isolated chondrocytes in the presence of a biological gel. Also featured in the invention are cartilage implants used to repair cartilage defects.
    Type: Application
    Filed: October 16, 2002
    Publication date: May 29, 2003
    Applicant: The general Hospital Corporation
    Inventors: David J. Zaleske, Giuseppe Peretti, Enzo Caruso, Francesco Rossetti, Mark Randolph
  • Bonding of cartilaginous matrices using isolated chondrocytes
    Publication number: 20010006634
    Abstract: Methods of bonding cartilage pieces using new cartilage matrix generated by isolated chondrocytes in the presence of a biological gel. Also featured in the invention are cartilage implants used to repair cartilage defects.
    Type: Application
    Filed: February 6, 2001
    Publication date: July 5, 2001
    Applicant: The General Hospital Corporation
    Inventors: David J. Zaleske, Giuseppe Peretti, Enzo Caruso, Francesco Rossetti, Mark Randolph
  • Bonding of cartilage pieces using isolated chondrocytes and a biological gel
    Patent number: 6183737
    Abstract: Isolated chondrocytes are propagated in the presence of a biological gel such as a fibrin gel to generate a cartilage matrix that firmly bonds together two adjacent cartilage pieces. A bonding composition containing the isolated chondrocytes mixed with the biological gel is applied to a surface of one (or both) of the cartilage pieces, and the surface is contacted with the other cartilage piece. In a different order of steps, the two cartilage pieces are held in apposition, and gaps at the interface are filled with the bonding composition. In another method, either or both of the cartilage pieces are first incubated with the isolated chondrocytes, the biological gel is then applied, and the cartilage pieces are held together. Alternatively, after incubating with isolated chondrocytes, the biological gel can be applied to fill gaps at the interface between cartilage pieces held in apposition.
    Type: Grant
    Filed: October 29, 1998
    Date of Patent: February 6, 2001
    Assignee: The General Hospital Corporation
    Inventors: David J. Zaleske, Giuseppe Peretti, Enzo Caruso, Francesco Rossetti, Mark Randolph