Abstract: A biosynthetic method for producing vitamin C (ascorbic acid, L-ascorbic acid, or AA) is disclosed. Such a method includes fermentation of a genetically modified microorganism or plant to produce L-ascorbic acid. In particular, the present invention relates to the use of microorganisms and plants having at least one genetic modification to increase the action of an enzyme involved in the ascorbic acid biosynthetic pathway. Included is the use of nucleotide sequences encoding epimerases, including the endogenous GDP-D-mannose:GDP-L-galactose epimerase from the L-ascorbic acid pathway and homologues thereof for the purposes of improving the biosynthetic production of ascorbic acid. The present invention also relates to genetically modified microorganisms, such as strains of microalgae, bacteria and yeast useful for producing L-ascorbic acid, and to genetically modified plants, useful for producing consumable plant food products.

Abstract: Lactobacillus delbrueckii sub-species bulgaricus ATCC-55163, a strain of Lactobacillus delbrueckii sub-species bulgaricus that can produce essentially stereoisometrically pure L-(+)-lactic acid, and a process for producing essentially stereoisometrically pure L-(+)-lactic acid using the strain are disclosed. A method for producing a mutant strain of Lactobacillus that produces essentially stereoisometrically pure lactic acid is also disclosed.