Patents by Inventor David Kiaei

David Kiaei has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11119108
    Abstract: Methods and reagents are disclosed for preparing a liquid solution of a receptor. The methods comprise combining in a liquid medium the receptor, a chelating agent and a C2-C6 polyol. An amount of the chelating agent and the C2-C6 polyol is sufficient to achieve a stable and active receptor in the liquid solution, which is maintained at a temperature of about 2° C. to about 40° C. The compositions may be employed in assays for the determination of analytes that include receptor-binding analytes.
    Type: Grant
    Filed: August 13, 2018
    Date of Patent: September 14, 2021
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventor: David Kiaei
  • Patent number: 10203338
    Abstract: Methods and reagents are disclosed for preparing a liquid solution of a receptor. The methods comprise combining in a liquid medium the receptor, a chelating agent and a C2-C6 polyol. An amount of the chelating agent and the C2-C6 polyol is sufficient to achieve a stable and active receptor in the liquid solution, which is maintained at a temperature of about 2° C. to about 40° C. The compositions may be employed in assays for the determination of analytes that include receptor-binding analytes.
    Type: Grant
    Filed: May 13, 2014
    Date of Patent: February 12, 2019
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventor: David Kiaei
  • Publication number: 20180356428
    Abstract: Methods and reagents are disclosed for preparing a liquid solution of a receptor. The methods comprise combining in a liquid medium the receptor, a chelating agent and a C2-C6 polyol. An amount of the chelating agent and the C2-C6 polyol is sufficient to achieve a stable and active receptor in the liquid solution, which is maintained at a temperature of about 2° C. to about 40° C. The compositions may be employed in assays for the determination of analytes that include receptor-binding analytes.
    Type: Application
    Filed: August 13, 2018
    Publication date: December 13, 2018
    Inventor: David Kiaei
  • Patent number: 10048273
    Abstract: Methods and reagents are disclosed for preparing a liquid solution of a receptor. The methods comprise combining in a liquid medium the receptor, a chelating agent and a C2-C6 polyol. An amount of the chelating agent and the C2-C6 polyol is sufficient to achieve a stable and active receptor in the liquid solution, which is maintained at a temperature of about 2° C. to about 40° C. The compositions may be employed in assays for the determination of analytes that include receptor-binding analytes.
    Type: Grant
    Filed: May 13, 2014
    Date of Patent: August 14, 2018
    Assignee: SIEMENS HEALTHCARE DIAGNOSTICS, INC.
    Inventor: David Kiaei
  • Publication number: 20160084847
    Abstract: Methods and reagents are disclosed for preparing a liquid solution of a receptor. The methods comprise combining in a liquid medium the receptor, a chelating agent and a C2-C6 polyol. An amount of the chelating agent and the C2-C6 polyol is sufficient to achieve a stable and active receptor in the liquid solution, which is maintained at a temperature of about 2° C. to about 40° C. The compositions may be employed in assays for the determination of analytes that include receptor-binding analytes.
    Type: Application
    Filed: May 13, 2014
    Publication date: March 24, 2016
    Inventor: David Kiaei
  • Patent number: 5710006
    Abstract: A sensitive assay method has been discovered that reduces the amount of non-specific binding present in an assay, the method comprising detecting an analyte present in a sample through a specific binding reaction in which either an analogue of the analyte or a specific binding partner of the analyte is immobilized on a solid-phase and said specific binding reaction produces a detectable product immobilized on said solid-phase that may be correlated to the amount of analyte present in the sample wherein said assay employs an effective amount of a surfactant selected from the group consisting of a polyoxyethylene-alkylether, a polyalkylene oxide-modified polydimethylsiloxane block copolymer, a polyalkylene oxide-modified polymethylsiloxane block copolymer, and mixtures thereof to reduce non-specific binding.
    Type: Grant
    Filed: March 19, 1997
    Date of Patent: January 20, 1998
    Assignee: Chiron Diagnostics Corporation
    Inventors: David Kiaei, Laurie A. Livshin, Uri Piran
  • Patent number: 5639626
    Abstract: A sensitive assay method has been discovered that reduces the amount of non-specific binding present in an assay, the method comprising detecting an analyte present in a sample through a specific binding reaction in which either an analogue of the analyte or a specific binding partner of the analyte is immobilized on a solid-phase and said specific binding reaction produces a detectable product immobilized on said solid-phase that may be correlated to the amount of analyte present in the sample wherein said assay employs an effective amount of a surfactant selected from the group consisting of a polyoxyethylene-alkylether, a polyalkylene oxide-modified polydimethylsiloxane block copolymer, a polyalkylene oxide-modified polymethylsiloxane block copolymer, and mixtures thereof to reduce non-specific binding.
    Type: Grant
    Filed: November 15, 1994
    Date of Patent: June 17, 1997
    Assignee: Chiron Diagnostics Corporation
    Inventors: David Kiaei, Laurie A. Livshin, Uri Piran
  • Patent number: 5055316
    Abstract: There is disclosed a method for producing extremely tight binding of proteins to surfaces and to a protein surface wherein the protein is tightly bound to the surface.
    Type: Grant
    Filed: April 20, 1988
    Date of Patent: October 8, 1991
    Assignee: Washington Research Foundation
    Inventors: Allan S. Hoffman, Thomas A. Horbett, Janice Bohnert, Bradford C. Fowler, David Kiaei