Patents by Inventor David Knight

David Knight has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immunoglobulin cleavage fragments and disease indicators and compositions for detecting and binding such
    Patent number: 9481734
    Abstract: The invention relates to antibody compositions and use of the composition to detect disease processes associated with elaboration of proteases. The reagents are directed to assessing an IgG breakdown product that is the result of such proteolytic cleavage. The invention further relates to the use of a therapeutic immunospecific for IgG protease cleavage products to restore effector function to antibody compositions that are subject to protease cleavage.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: November 1, 2016
    Assignee: Janssen Biotech, Inc.
    Inventors: Robert Jordan, David Knight, Randall Brezski, Mary Ryan, Diane Petrone
  • End-To-End Secure Cloud Computing
    Publication number: 20160261637
    Abstract: A method includes receiving, at a control node of a cloud computing network, a first enterprise policy specific to the first enterprise and a second enterprise policy specific to the second enterprise, and managing communications between at least one user device of the first enterprise and the at least one enterprise application hosted on behalf of the first enterprise based on the first enterprise policy. The method also includes managing communications between at least one user device of the second enterprise and the at least one enterprise application hosted on behalf of the second enterprise based on the second enterprise policy.
    Type: Application
    Filed: May 12, 2016
    Publication date: September 8, 2016
    Applicant: AT&T Intellectual Property I, L.P.
    Inventors: Gustavo de los Reyes, William R. Beckett, Jerry Birkes, Deepak K. Chawla, Joshua David Knight, Sanjay Macwan, William O'Hern
  • Method of treating Crohn's disease by administering an anti-IL-12 antibody
    Patent number: 9428579
    Abstract: An anti-IL-12 antibody that binds to a portion of the IL-12 protein corresponding to at least one amino acid residue selected from the group consisting of residues 15, 17-21, 23, 40-43, 45-47, 54-56 and 58-62 of the amino acid sequence of the p40 subunit of IL-12, including isolated nucleic acids that encode at least one anti-IL-12 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.
    Type: Grant
    Filed: October 13, 2014
    Date of Patent: August 30, 2016
    Assignee: Janssen Biotech, Inc.
    Inventors: Jill Giles-Komar, George Heavner, David Knight, Jinquan Luo, David Peritt, Bernard Scallon, David Shealy
  • USER MESSAGING BASED ON CHANGES IN TRACKED ACTIVITY METRICS
    Publication number: 20160234143
    Abstract: A system comprising at least one server computer having at least one processor programmed to: receive, over a network, activity data of a first user measured by an activity monitoring device; process the activity data of the first user to update a value of an activity metric for the first user; responsive to updating the value of the activity metric for the first user, identify a change in an inequality relationship between the value of the activity metric for the first user and a value of the activity metric for a second user; and, responsive to identifying the change in the inequality relationship, trigger, over the network, a first user device to prompt the first user to generate a message to the second user for display on a second user device.
    Type: Application
    Filed: April 14, 2016
    Publication date: August 11, 2016
    Inventors: Nichiketa Choudhary, Timothy Roberts, David Knight
  • Indoles
    Patent number: 9402836
    Abstract: Herein are disclosed indoles of formula (I) where the various groups are defined herein, and which are useful for treating cancer.
    Type: Grant
    Filed: July 9, 2015
    Date of Patent: August 2, 2016
    Assignee: GlaxoSmithKline LLC
    Inventors: James Brackley, III, Joelle Lorraine Burgess, Seth Wilson Grant, Neil W. Johnson, Steven David Knight, Louis Vincent LaFrance, III, William Henry Miller, Kenneth Allen Newlander, Stuart Paul Romeril, Meagan B. Rouse, Xinrong Tian, Sharad Kumar Verma
  • End-to-end secure cloud computing
    Patent number: 9392023
    Abstract: A method includes receiving, at a control node of a cloud computing network, a first enterprise policy specific to the first enterprise and a second enterprise policy specific to the second enterprise, and managing communications between at least one user device of the first enterprise and the at least one enterprise application hosted on behalf of the first enterprise based on the first enterprise policy. The method also includes managing communications between at least one user device of the second enterprise and the at least one enterprise application hosted on behalf of the second enterprise based on the second enterprise policy.
    Type: Grant
    Filed: October 7, 2014
    Date of Patent: July 12, 2016
    Assignee: AT&T INTELLECTUAL PROPERTY I, L.P.
    Inventors: Gustavo de los Reyes, Willam R. Beckett, Jerry Birkes, Deepak K. Chawla, Joshua David Knight, Sanjay Macwan, William O'Hern
  • Enhancer of Zeste Homolog 2 inhibitors
    Patent number: 9382234
    Abstract: This invention relates to novel compounds according to Formula (I) which are inhibitors of Enhancer of Zeste Homolog 2 (EZH2), to pharmaceutical compositions containing them, to processes for their preparation, and to their use in therapy for the treatment of cancers.
    Type: Grant
    Filed: December 12, 2013
    Date of Patent: July 5, 2016
    Assignee: GlaxoSmithKline LLC
    Inventors: Steven David Knight, William Henry Miller, Kenneth Allen Newlander, Carla A. Donatelli
  • Fitness activity related messaging
    Patent number: 9344546
    Abstract: In one embodiment, a method for generating a message to a friend of a user is provided, comprising: processing activity data of a first user measured by an activity monitoring device to update a value of an activity metric for the first user; identifying a change in an inequality relationship between the value of the activity metric for the first user and a value of the activity metric for a second user; in response to identifying the change in the inequality relationship, prompting the first user to generate a message to the second user.
    Type: Grant
    Filed: July 28, 2014
    Date of Patent: May 17, 2016
    Assignee: Fitbit, Inc.
    Inventors: Nichiketa Choudhary, Timothy Roberts, David Knight
  • ENHANCER OF ZESTE HOMOLOG 2 INHIBITORS
    Publication number: 20160130261
    Abstract: This invention relates to novel compounds according to Formula (I) which are inhibitors of Enhancer of Zeste Homolog 2 (EZH2), to pharmaceutical compositions containing them, to processes for their preparation, and to their use in therapy for the treatment of cancers.
    Type: Application
    Filed: July 9, 2014
    Publication date: May 12, 2016
    Inventors: Joelle Lorraine BURGESS, Steven David KNIGHT
  • ENHANCER OF ZESTE HOMOLOG 2 INHIBITORS
    Publication number: 20160122342
    Abstract: This invention relates to novel compounds according to Formula (I) which are inhibitors of Enhancer of Zeste Homolog 2 (EZH2), to pharmaceutical compositions containing them, to processes for their preparation, and to their use in therapy for the treatment of cancers.
    Type: Application
    Filed: June 6, 2014
    Publication date: May 5, 2016
    Inventors: David T. FOSBENNER, Bryan W. KING, Steven David KNIGHT, Louis Vincent LaFRANCE, III, Mei LI, Kenneth C. McNULTY, Stuart Paul ROMERIL, Mark Andrew SEEFELD
  • Malicious Message Detection and Processing
    Publication number: 20160127399
    Abstract: Malicious message detection and processing systems and methods are provided herein. According to various embodiments, a method includes detecting, via an intermediary node, a link included in a message, the link being associated with an unknown resource, hashing a unique identifier for a recipient of the message, coupling the hashed identifier with the link, creating an updated link and updated message, and forwarding the updated message to the recipient.
    Type: Application
    Filed: January 11, 2016
    Publication date: May 5, 2016
    Inventors: Angelo Starink, David Knight
  • ENHANCER OF ZESTE HOMOLOG 2 INHIBITORS
    Publication number: 20160102083
    Abstract: This invention relates to novel compounds according to Formula (I) which are inhibitors of Enhancer of Zeste Homolog 2 (EZH2), to pharmaceutical compositions containing them, to processes for their preparation, and to their use in therapy for the treatment of cancers.
    Type: Application
    Filed: April 25, 2014
    Publication date: April 14, 2016
    Applicant: GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED
    Inventors: Charles William BLACKLEDGE, JR., Joelle Lorraine BURGESS, Neil W. JOHNSON, Jiri KASPAREC, Steven David KNIGHT, Louis V. LaFRANCE, III, Juan I. LUENGO, William Henry MILLER, Kenneth Allen NEWLANDER, Stuart Paul ROMERIL, Mark SCHULZ, Dai-Shi SU, Xinrong TIAN
  • End-To-End Secure Cloud Computing
    Publication number: 20160099971
    Abstract: A method includes receiving, at a control node of a cloud computing network, a first enterprise policy specific to the first enterprise and a second enterprise policy specific to the second enterprise, and managing communications between at least one user device of the first enterprise and the at least one enterprise application hosted on behalf of the first enterprise based on the first enterprise policy. The method also includes managing communications between at least one user device of the second enterprise and the at least one enterprise application hosted on behalf of the second enterprise based on the second enterprise policy.
    Type: Application
    Filed: October 7, 2014
    Publication date: April 7, 2016
    Inventors: Gustavo de los Reyes, Willam R. Beckett, Jerry Birkes, Deepak K. Chawla, Joshua David Knight, Sanjay Macwan, William O'Hern
  • Malicious message detection and processing
    Patent number: 9241009
    Abstract: Malicious message detection and processing systems and methods are provided herein. According to various embodiments, a method includes detecting, via an intermediary node, a link included in a message, the link being associated with an unknown resource, hashing a unique identifier for a recipient of the message, coupling the hashed identifier with the link, creating an updated link and updated message, and forwarding the updated message to the recipient.
    Type: Grant
    Filed: September 15, 2014
    Date of Patent: January 19, 2016
    Assignee: Proofpoint, Inc.
    Inventors: Angelo Starink, David Knight
  • MALICIOUS MESSAGE DETECTION AND PROCESSING
    Publication number: 20150381653
    Abstract: Malicious message detection and processing systems and methods are provided herein. According to various embodiments, a method includes detecting, via an intermediary node, a link included in a message, the link being associated with an unknown resource, hashing a unique identifier for a recipient of the message, coupling the hashed identifier with the link, creating an updated link and updated message, and forwarding the updated message to the recipient.
    Type: Application
    Filed: September 15, 2014
    Publication date: December 31, 2015
    Inventors: Angelo Starink, David Knight
  • Thieno[3,2-c]pyridine potassium channel inhibitors
    Patent number: 9216992
    Abstract: The present invention provides thienopyridine compounds which are potassium channel inhibitors. In another embodiment, the invention provides pharmaceutical compositions comprising thienopyridines. In another embodiment, the invention provides methods of using thienopyridines in the treatment or prevention of cancer, arrhythmias, autoimmune diseases and inflammatory diseases, including gastric cancer, atrial fibrillation, type-2 diabetes mellitus, rheumatoid arthritis, type-1 diabetes, inflammatory bowel disorder and demyelinating disorders such as multiple sclerosis.
    Type: Grant
    Filed: December 8, 2006
    Date of Patent: December 22, 2015
    Assignee: Xention Limited
    Inventors: John Ford, David John Madge, Helen Jane Payne, Jamie David Knight
  • System and method for backing up a computer system
    Patent number: 9218345
    Abstract: A backup computer storage system that protects and/or recovers data on a primary computer storage system is disclosed. The backup computer system may be used to backup databases, files, and/or applications. In some embodiments, the backup system may be used to backup an image of the primary computer storage system. In other embodiments, the backup system may be used to backup one or more databases, replicate an image of data that is on the primary computer storage system, restore data from the backup system to the primary computer storage system, restore data to a database while non-affected portions of the database are available and can be used, record all transactions in real time without overwriting any previously stored backup data, and maintain historical and/or chronological information related to backed up data.
    Type: Grant
    Filed: August 19, 2009
    Date of Patent: December 22, 2015
    Assignee: Symantec Corporation
    Inventors: Gregory A. Becker, Robert Condon, David A. Knight, David E. Medders, Michael Rowan
  • Floating marine dock and connection system therefor
    Patent number: 9206570
    Abstract: A floating marine dock and connection system there for provides plural elongate rectilinear flotation pontoons having a consistent peripheral configuration with a major dimension and a minor dimension and customizable lengths. Connection apparatus interconnected to the flotation pontoons permits the flotation pontoons to be interconnected end-to-end, in parallel, perpendicular to, and spaced apart from one another. Connection straps extend about the outer periphery of the flotation pontoons and interconnect with flanges, plates and accessories desirable for marine docks. The connection straps support a nailer beam to which decking is fastened. Braces extend between spacedly adjacent flotation pontoons to maintain the spatial relationship therebetween and to support service conduits.
    Type: Grant
    Filed: June 26, 2013
    Date of Patent: December 8, 2015
    Assignee: Knight Boat Docks, LLC
    Inventors: Douglas J. Knight, Kenneth L. Knight, David A. Knight, David Drahman
  • INDOLES
    Publication number: 20150313887
    Abstract: Herein are disclosed indoles of formula (I) where the various groups are defined herein, and which are useful for treating cancer.
    Type: Application
    Filed: July 9, 2015
    Publication date: November 5, 2015
    Inventors: James BRACKLEY, III, Joelle Lorraine Burgess, Seth Wilson Grant, Neil W. Johnson, Steven David Knight, Louis Vincent LaFrance, III, William Henry Miller, Kenneth Allen Newlander, Stuart Paul Romeril, Meagan B. Rouse, Xinrong Tian, Sharad Kumar Verma
  • ENHANCER OF ZESTE HOMOLOG 2 INHIBITORS
    Publication number: 20150307480
    Abstract: This invention relates to novel compounds according to Formula (I) which are inhibitors of Enhancer of Zeste Homolog 2 (EZH2), to pharmaceutical compositions containing them, to processes for their preparation, and to their use in therapy for the treatment of cancers.
    Type: Application
    Filed: December 12, 2013
    Publication date: October 29, 2015
    Inventors: Steven David KNIGHT, William Henry MILLER, Kenneth Allen NEWLANDER, Carla A. DONATELLI