Patents by Inventor David L. Bartlett

David L. Bartlett has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IL-36 CYTOKINE EXPRESSING ONCOLYTIC VIRUSES FOR TREATING CANCER
    Publication number: 20220211814
    Abstract: The present disclosure provides interleukin-36 (IL-36) cytokine (e.g., IL-36?) expressing oncolytic viruses, and compositions comprising thereof. The present disclosure further provides methods of using said oncolytic viruses and compositions for treating cancer, and for improving a subject's responsiveness to an immunomodulatory agent.
    Type: Application
    Filed: March 17, 2022
    Publication date: July 7, 2022
    Applicant: UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
    Inventors: Zong Sheng GUO, Binfeng LU, David L. BARTLETT
  • Vaccinia virus expression vector for selective replication in a tumor cell and introduction of exogenous nucleotide sequence into a tumor cell
    Patent number: 8506947
    Abstract: A composition of matter comprising a vaccinia virus expression vector with a negative thymidine kinase phenotype and a negative vaccinia virus growth factor phenotype.
    Type: Grant
    Filed: February 16, 2007
    Date of Patent: August 13, 2013
    Assignee: The United States of America as Represented by the Secretary of the Department of Health and Human Services
    Inventors: J. Andrea McCart, David L. Bartlett, Bernard Moss
  • Combined growth factor-deleted and thymidine kinase-deleted vaccinia virus vector
    Patent number: 7208313
    Abstract: A composition of matter comprising a vaccinia virus expression vector with a negative thymidine kinase phenotype and a negative vaccinia virus growth factor phenotype.
    Type: Grant
    Filed: November 13, 2001
    Date of Patent: April 24, 2007
    Assignee: United States of America as represented by the Secretary of the Department of Health and Human Services
    Inventors: J. Andrea McCart, David L. Bartlett, Bernard Moss
  • Combined growth factor-deleted and thymidine kinase-deleted vaccinia virus vector
    Publication number: 20030031681
    Abstract: A composition of matter comprising a vaccinia virus expression vector with a negative thymidine kinase phenotype and a negative vaccinia virus growth factor phenotype.
    Type: Application
    Filed: November 13, 2001
    Publication date: February 13, 2003
    Inventors: J. Andrea McCart, David L. Bartlett, Bernard Moss
  • Grommet having metal insert
    Patent number: 6114629
    Abstract: The invention is directed to a grommet including a cylindrical body fabried from rubber or synthetic rubber material. The body has a centrally located aperture extending therethrough and at least one radially located aperture with a slit for easily receiving a cable or the like. The grommet further includes a rigid insert secured to the body in the centrally located aperture. The insert has female threads formed therein for releasably securing a tool thereto to remove the grommet from the ballast tank without destroying the body of the grommet. The insert has a tubular member and an outwardly projecting circumferential flange formed on the tubular member. The body is formed on the tubular member wherein the flange secures the insert axially with respect to the body. Preferably, the body is fabricated from neoprene and is vulcanized to its final form.
    Type: Grant
    Filed: September 28, 1998
    Date of Patent: September 5, 2000
    Assignee: The United States of America as represented by the Secretary of the Navy
    Inventors: Robert A. Roush, David L. Bartlett, William T. Young, Jr., Austin H. Wolfe