Abstract: A new immunoassay system is provided for the detection of ligands or ligand binding partners in solution in a heterogeneous format. The invention relies upon the detection of back scattered light from an evanescent wave disturbed by the presence of a colloidal gold label brought to the interface by an immunological reaction. The evanescent wave existing at the interface in turn is the result of a totally internally reflected incident light wave. Placement of the detector at a back angle above the critical angle insures a superior signal-to-noise ratio.

Abstract: A new immunoassay system is provided for the detection of ligands or ligand binding partners in solution in a heterogeneous format. The invention relies upon the detection of back scattered light from an evanescent wave disturbed by the presence of a colloidal gold label brought to the interface by an immunological reaction. The evanescent wave existing at the interface in turn is the result of a totally internally reflected incident light wave. Placement of the detector at a back angle above the critical angle insures a superior signal-to-noise ratio. Apparatus and methods for scanning, detecting and manipulating light including a scattered total internal reflectance immunoassay system are provided.

Abstract: An ultrasonic diagnostic probe is provided which performs simultaneous ultrasonic imaging and Doppler flow measurement. The Doppler transducer is mounted for rotation by a mechanical assembly, which permits the Doppler beam to be steered during imaging to the point in the body where a flow measurement is to be taken. As the Doppler transducer is rotated, a variable impedance device within the probe is adjusted in correspondence with the transducer rotation so as to provide an indication signal of the direction in which the Doppler beam is being directed.

Abstract: An apparatus and method are disclosed for dispensing adhesive materials, with the apparatus being self-cleaning for changeover of the adhesive supply.Adhesive is provided in a sealed container, which can be subjected to pressure. As the container is subjected to increased pressure, some of the adhesive travels upwardly through a dip tube and exits through an opening in the lid in the container. The dip tube communicates with a flexible conduit which leads to a dispenser for the adhesive. The adhesive travels through the dip tube, flexible conduit and dispenser in a first, outward direction when the adhesive is being dispensed.To purge the dip tube, flexible conduit and dispenser of adhesive, the open end of the dispenser is operably connected to a source of compressed air, and the air enters the dispenser, and travels through the flexible conduit and the dip tube until it enters the container.

Abstract: A connector is provided for attachment of a syringe to a dispenser adapted to provide measured quantities of pressured gas to the syringe to displace the contents of the syringe in measured drops. The connector includes a flexible conduit attached at one end to the dispenser and attached at its opposite end to the filling end of a syringe while gripping the oppositely disposed projections, or "ears", of the syringe. There is an externally threaded tube at the syringe end of the flexible conduit, terminated by a stopper member which has a cylindrical end portion sized to fit loosely within the filling end of the syringe, which end portion is joined to a sealing flange. The sealing flange abuts the flat surface at the filling end of the syringe while the syringe "ears" are retained within oppositely disposed channels after a knurled ring on the externally threaded tubular member is rotated.

Abstract: System for printing particular information-bearing symbols corresponding to data emanating from a source comprising: source means capable of generating data in a particular sequence; memory means for storing information-bearing symbols; selection means for selecting particular symbols from said memory means corresponding to data emanating from said source; said selection means ordering said particular symbols in a predetermined sequence for printing; a medium adapted to bear printed information-bearing symbols; and transmitting means for transmitting each of said particular characters from said memory means to said medium.