Patents by Inventor David L. Henderson
David L. Henderson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11970479Abstract: The present invention is directed to cinnolinyl and quinolinyl pyrazol-4-yl-pyridine compounds which are allosteric modulators of the M4 muscarinic acetylcholine receptor. The present invention is also directed to uses of the compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which M4 muscarinic acetylcholine receptors are involved. The present invention is also directed to compositions comprising these compounds. The present invention is also directed to uses of these compositions in the potential prevention or treatment of such diseases in which M4 muscarinic acetylcholine receptors are involved.Type: GrantFiled: October 24, 2019Date of Patent: April 30, 2024Assignees: Merck Sharp & Dohme LLC, MSD R&D (China) Co. LTD.Inventors: John J. Acton, III, Melissa Egbertson, Xiaolei Gao, Scott T. Harrison, Timothy J. Henderson, Michael Man-Chu Lo, Robert D. Mazzola, Jr., Zhaoyang Meng, James Mulhearn, Vanessa L. Rada, Jeffrey W. Schubert, Oleg B. Selyutin, David M. Tellers, Ling Tong, Fengqi Zhang, Jianming Bao, Chunsing Li
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Patent number: 8396269Abstract: Image quality is assessed for a digital image that is a composite of tiles or other image segments, especially focus accuracy for a microscopic pathology sample. An algorithm or combination of algorithms correlated to image quality is applied to pixel data at margins where adjacent image segments overlap and thus contain the same content in separately acquired images. The margins may be edges merged to join the image segments smoothly into a composite image, and typically occur on four sides of the image segments. The two versions of the same image content at each margin are processed by the quality algorithm, producing two assessment values. A sign and difference value are compared with other image segments, including by subsets selected for the orientation of the margins on sides on the image segments. The differences are mapped to displays. Selection criteria determine segments to be re-acquired.Type: GrantFiled: April 8, 2010Date of Patent: March 12, 2013Assignee: Digital Pathco LLCInventors: David L. Henderson, Kevin B. Kenny, Dirk R. Padfield, Dashan Gao, Richard R. McKay, Vipul A. Baxi, Robert J. Filkins, Michael C. Montalto
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Publication number: 20110249910Abstract: Image quality is assessed for a digital image that is a composite of tiles or other image segments, especially focus accuracy for a microscopic pathology sample. An algorithm or combination of algorithms correlated to image quality is applied to pixel data at margins where adjacent image segments overlap and thus contain the same content in separately acquired images. The margins may be edges merged to join the image segments smoothly into a composite image, and typically occur on four sides of the image segments. The two versions of the same image content at each margin are processed by the quality algorithm, producing two assessment values. A sign and difference value are compared with other image segments, including by subsets selected for the orientation of the margins on sides on the image segments. The differences are mapped to displays. Selection criteria determine segments to be re-acquired.Type: ApplicationFiled: April 8, 2010Publication date: October 13, 2011Applicants: General Electric Company, Omnyx LLCInventors: David L. Henderson, Kevin B. Kenny, Dirk R. Padfield, Dashan Gao, Richard R. McKay, Vipul A. Baxi, Robert J. Filkins, Michael C. Montalto
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Patent number: 7506877Abstract: An apparatus, method and system for extending working tool or bit from a source of rotary power, including a body with a shank, blind bore for the shank of the tool or bit, a tangential bore, a clamping member insertable through one end of the clamping bore, the clamping member having an internal threaded bore, a threaded fastener inserted through the other end of the clamping bore into the threaded bore of the clamping member, an opening into the blind bore into which a wedging section of the clamping member can be drawn tangentially by action of the threaded member.Type: GrantFiled: January 13, 2006Date of Patent: March 24, 2009Inventors: David L. Henderson, Robert E. McFarlin, Jr.
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Patent number: 7172377Abstract: An extension for a bit or cutter tool relative to a rotational power source. The extension includes a blind bore receiving the shank of the bit or cutter. The opposite end of the body has structure that can be operatively connected to the source of rotational power. A second bore through the side of the body intersects the first bore. The second bore has two portions. The inner-most portion has a smaller diameter and is internally threaded. The outer portion has a larger diameter and slidably receives a clamping member. Clamping member can be retained by a shoulder bolt and has an end that can enter into the blind bore to clamp the shank in place. Preferably the clamping member is a sleeve having a center bore and a concentric exterior. Another aspect of the invention includes a biasing means that biases the sleeve outward of the bore.Type: GrantFiled: December 30, 2004Date of Patent: February 6, 2007Inventors: Robert E. McFarlin, Jr., David L. Henderson
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Patent number: 7027723Abstract: Electrical components projecting outwardly from the storage tank portion of an electric water heater are shielded from foam insulation material being injected into an insulation space between the tank and an outer jacket portion of the water heater by a hollow, open sided foam dam structure extending through a jacket opening and circumscribing the electrical components. Force exerting projections on the dam engage the interior side surface of the jacket and forcibly hold the inner side of the dam structure in sealing engagement with the tank. The projections also hold an outer side peripheral lip of the dam in a an outwardly and resiliently deflected orientation in which it is sealingly pressed inwardly against the outer side surface of the jacket around the periphery of the opening therein to prevent injected foam from being forced outwardly through the jacket opening.Type: GrantFiled: July 9, 2004Date of Patent: April 11, 2006Assignee: Rheem Manufacturing CompanyInventors: David L. Henderson, Jozef Boros, Kenneth J. Hicks
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Patent number: 6917756Abstract: Electrical components projecting outwardly from the storage tank portion of an electric water heater are shielded from foam insulation material being injected into an insulation space between the tank and an outer jacket portion of the water heater by a hollow, open sided foam dam structure extending through a jacket opening and circumscribing the electrical components. Force exerting projections on the dam engage the interior side surface of the jacket and forcibly hold the inner side of the dam structure in sealing engagement with the tank. The projections also hold an outer side peripheral lip of the dam in a an outwardly and resiliently deflected orientation in which it is sealingly pressed inwardly against the outer side surface of the jacket around the periphery of the opening therein to prevent injected foam from being forced outwardly through the jacket opening.Type: GrantFiled: July 1, 2003Date of Patent: July 12, 2005Assignee: Rheem Manufacturing CompanyInventors: David L. Henderson, Jozef Boros, Kenneth J. Hicks
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Patent number: 6898375Abstract: Electrical components projecting outwardly from the storage tank portion of an electric water heater are shielded from foam insulation material being injected into an insulation space between the tank and an outer jacket portion of the water heater by a hollow, open sided foam dam structure extending through a jacket opening and circumscribing the electrical components. Force exerting projections on the dam engage the interior side surface of the jacket and forcibly hold the inner side of the dam structure in sealing engagement with the tank. The projections also hold an outer side peripheral lip of the dam in a an outwardly and resiliently deflected orientation in which it is sealingly pressed inwardly against the outer side surface of the jacket around the periphery of the opening therein to prevent injected foam from being forced outwardly through the jacket opening.Type: GrantFiled: July 9, 2004Date of Patent: May 24, 2005Assignee: Rheem Manufacturing CompanyInventors: David L. Henderson, Jozef Boros, Kenneth J. Hicks
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Patent number: 6885816Abstract: A foam dam in the insulation cavity of an electric water heater comprises a plastic bag into which liquid foam insulation is injected, the bag having an essentially closed top edge portion with only a small opening for receiving the injected insulation. A small portion of the insulation injected into the bag is forced outwardly therefrom via small metering holes to form external protrusions on the bag that mechanically interlock with a second batch of insulation subsequently injected into the cavity and prevent the hardened second insulation batch from pulling away from the bag. The substantially closed top edge of the bag permits the insulation injected into the bag to pack therein and increase the top-to-bottom hardened foam density uniformity. Side edges of the bag may be pleated to increase the sealing area of the foam dam.Type: GrantFiled: November 3, 2003Date of Patent: April 26, 2005Assignee: Rheem Manufacturing CompanyInventors: Kenneth J. Hicks, David L. Henderson, Jozef Boros
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Publication number: 20040128698Abstract: A television network broadcast system includes a scheduling component that includes a user interface accessible by all users who contribute to the creation of a schedule and a plurality of nodes configured to perform actions based on receipt of messages. The nodes include at least one of groups, filters, clients, and servers. The actions include at least one of pass the message along, take a specific action based on receipt of a specific message, block certain types of messages, and initiate new messages.Type: ApplicationFiled: December 31, 2002Publication date: July 1, 2004Inventors: Helena Goldfarb, Kevin Kenny, Jonathan Houlihan, Jesse Schechter, Benjamin Verschueren, Li Liao, Jill Magsam, Stephen Angelovich, Michael Kinstrey, Brion D. Sarachan, Michael A. Woellmer, David L. Henderson, Christopher Hammond
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Patent number: 6745723Abstract: Convective heat traps are installed at the cold water inlet and hot water outlet of a water heater. Each heat trap has a tubular body with two axially spaced apart resilient flapper members transversely extending across the interior of the body and being hinged on opposite sides thereof. The heat trap at the cold water inlet is coaxially disposed within a dip tube. In one alternate structure, flapper members are mounted directly on the dip tube, and in another alternate structure an external annular seal element is mounted on the dip tube or heat trap body, with a flapper member being integrally formed with the seal element.Type: GrantFiled: July 2, 2003Date of Patent: June 8, 2004Assignee: Rheem Manufacturing CompanyInventors: Kenneth J. Hicks, David L. Henderson, Jozef Boros
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Publication number: 20030135529Abstract: An apparatus and method are provided for performing both forward and inverse Haar transforms of a sequence of n-bit data samples. The forward Haar transform apparatus has sum-and-truncate logic and a plurality of coefficient generators. The sum-and-truncate logic generates a plurality of n-bit intermediate terms. The plurality of coefficient generators is coupled to the sum-and-truncate logic. The plurality of coefficient generators generate a plurality of spectral coefficients, where at most n+1 bits are required to represent each of the plurality of spectral coefficients. The inverse Haar transform apparatus has index signal and inverse transform logic. The index signal indicates a specific n-bit sample, the specific n-bit sample being one of a sequence of n-bit samples corresponding to the Haar transform. The inverse transform logic is coupled to the index signal.Type: ApplicationFiled: January 11, 2003Publication date: July 17, 2003Applicant: Spectral Logic Design CorporationInventor: David L. Henderson
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Patent number: 6588378Abstract: A water heater is provided with a specially designed molded bottom pad/foam dam member formed from a crushable material, such as polystyrene, which is received in a metal bottom pan and has concentric circular grooves formed in its top side to receive circular bottom end edge portions of the tank and outer jacket portions of the water heater. A circumferentially spaced plurality of rigid support members are imbedded in the bottom pad/foam dam member and underlie its tank groove to prevent the tank from crushing the member one of the support members is formed from an electrically conductive material and defines an electrical grounding path between the tank and the bottom pan, and the other support members are formed from a thermally insulative material to inhibit heat loss from the tank to the bottom pan.Type: GrantFiled: August 28, 2002Date of Patent: July 8, 2003Assignee: Rheem Manufacturing CompanyInventors: David L. Henderson, Jozef Boros
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Patent number: 6587862Abstract: An apparatus and method are provided for synthesizing a variable frequency sinusoidal waveform. The apparatus and method exploit octant symmetry properties of sine and cosine waveforms, when taken together. The digital frequency synthesis apparatus includes a phase signal and a phase-to-amplitude converter. The phase signal indicates a desired phase angle of the sinusoidal waveform. The phase-to-amplitude converter is coupled to the phase signal. The phase-to-amplitude converter provides a desired amplitude sample corresponding to the desired phase angle, where the desired amplitude sample is derived from amplitude samples corresponding to an octant of the sinusoidal waveform. The phase-to-amplitude converter includes a Haar Transform-based coarse octant amplitude sample generator that computes Haar coefficients corresponding to the phase signal and transforms the Haar coefficients into the desired amplitude sample.Type: GrantFiled: September 7, 1999Date of Patent: July 1, 2003Assignee: Spectral Logic DesignInventor: David L. Henderson
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Patent number: 6557019Abstract: An apparatus and method are provided for performing both forward and inverse Haar transforms of a sequence of n-bit data samples. The forward Haar transform apparatus has sum-and-truncate logic and a plurality of coefficient generators. The sum-and-truncate logic generates a plurality of n-bit intermediate terms. The plurality of coefficient generators is coupled to the sum-and-truncate logic. The plurality of coefficient generators generate a plurality of n+1-bit spectral coefficients. The inverse Haar transform apparatus has index signal and inverse transform logic. The index signal indicates a specific n-bit sample, the specific n-bit sample being one of a sequence of n-bit samples corresponding to the Haar transform. The inverse transform logic is coupled to the index signal. The inverse transform logic computes the specific n-bit sample, where the specific n-bit sample is derived from selected n+1-bit spectral coefficients.Type: GrantFiled: September 7, 1999Date of Patent: April 29, 2003Assignee: Spectral Logic DesignInventor: David L. Henderson
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Patent number: 6520227Abstract: An apparatus to support a hand held motorized tool in an inverted position that allows easy removal of the tool for hand held purposes. The apparatus is defined by a receiver in a frame and an opening for removal of the tool. A lid may further stabilize the tool. When mounted in the receiver the lateral and upper movement of the tool is restricted. When removed from the receiver the tool has attached to it only a sub base-plate that is comparable in size to the tool. The receiver may be removable or built into a tabletop.Type: GrantFiled: August 8, 2001Date of Patent: February 18, 2003Inventors: Robert E. Mc Farlin, Jr., David L. Henderson
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Publication number: 20020020466Abstract: An apparatus to support a hand held motorized tool in an inverted position that allows easy removal of the tool for hand held purposes. The apparatus is defined by a receiver in a frame and an opening for removal of the tool. A lid may further stabilize the tool. When mounted in the receiver the lateral and upper movement of the tool is restricted. When removed from the receiver the tool has attached to it only a sub base-plate that is comparable in size to the tool. The receiver may be removable or built into a tabletop.Type: ApplicationFiled: August 8, 2001Publication date: February 21, 2002Inventors: Robert E. Mc Farlin, David L. Henderson
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Patent number: 6318936Abstract: A plunge router adjustment mechanism including a drive shaft longitudinally fixed but rotatable in a base plate and extending towards an opposite end of the plunge router. A carriage moveable along the drive shaft is connectable to the router housing. Optionally, a sub-carriage, moveable along the carriage and directly attached to the housing, allows fine adjustment of the housing relative to the base plate. Optionally a coarse adjustment stop member is releasably fixable along the drive shaft for coarse positioning of the housing relative to base plate.Type: GrantFiled: June 13, 2000Date of Patent: November 20, 2001Inventors: Robert E. McFarlin, Jr., David L. Henderson
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Patent number: 6271505Abstract: An electric water heater has upper and lower electric resistance type heating elements respectively controlled by a single pole, double throw upper thermostat and a single pole, single throw lower thermostat. The upper and lower thermostats are operatively interconnected by a wiring harness having outer wire end portions that may be connected in various orientations to the terminal block portion of an external junction box to provide the water heater with a variety of heating element operating modes without having to replace either of the thermostats or vary the wiring harness interconnections therebetween. The water heater may thus be advantageously manufactured in a single variant that may be easily and quickly modified in the field to selectively alter the heating element control mode of the water heater.Type: GrantFiled: February 16, 2000Date of Patent: August 7, 2001Assignee: Rheem Manufacturing CompanyInventor: David L. Henderson
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Patent number: 6239512Abstract: An electric water heater is provided with simplified phase conversion apparatus including a terminal structure having replaceable line lug portions which are wired to a single phase row of multi-pin connector sockets by single phase routing circuitry, and to a three phase row of multi-pin connector sockets by three phase routing circuitry. Electrical supply wires from sets of fuse holders connected to multiple thermostat/heating element sets are grouped and connected to associated multi-pin connector plugs. To ready the water heater for single phase operation, the plugs are connected to the single phase row of sockets, and to convert the water heater to three phase operation the plugs are simply disconnected from the single phase sockets and connected to the three phase sockets. In this manner the necessity of individually repositioning all of the fuse holder wires on the terminal structure to change from single to three phase operation, or vice versa, is eliminated.Type: GrantFiled: July 28, 1999Date of Patent: May 29, 2001Assignee: Rheem Manufacturing CompanyInventors: David L. Henderson, Timothy E. Powell