Patents by Inventor David Lavie

David Lavie has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antiviral agents
    Patent number: 6576784
    Abstract: Novel antiviral (including antiretroviral) compounds are mono- or dicarboxylic acid esters of hypericin in which one or both of the methyl groups of hypericin are substituted by carboxylic acid ester groups of the formula COOR3 in which R3 is alkyl, the chain of which is optionally interrupted by one or more oxygen or sulphur atoms. R3 is preferably methyl, ethyl, propyl, butyl, 2-methoxyethyl or 2-(2-methoxyethoxy)ethyl. The compounds may be formulated into pharmaceutical compositions and may be used in any manner which has previously been known for hypericin.
    Type: Grant
    Filed: May 27, 1993
    Date of Patent: June 10, 2003
    Assignees: Yeda Research and Development Co. Ltd., New York University
    Inventors: Yehuda Mazur, Gad Lavie, Daniel Meruelo, David Lavie
  • Plant extracts for the preparation of pharmaceutical compositions for the treatment of hepatitis
    Patent number: 6428819
    Abstract: The use of extracts from the plant Hypericum perforatum in the preparation of pharmaceutical compositions for the treatment of hepatitis C, chronic hepatitis C and related viruses, said pharmaceutical compositions comprising at least one extract of the plant Hypericum perforatum and optionally in addition, one or more pharmaceutically acceptable inactive components, selected from, carriers, coatings, diluents and adjuvants.
    Type: Grant
    Filed: April 4, 2000
    Date of Patent: August 6, 2002
    Inventors: David Lavie, Anne Steinbeck-Klose
  • Plant extracts for the preparation of pharmaceutical compositions for the treatment of hepatitis
    Patent number: 6056961
    Abstract: The use of extracts from the plant Hypericum perforatum in the preparation of pharmaceutical compositions for the treatment of hepatitis C, chronic hepatitis C and related viruses, said pharmaceutical compositions comprising at least one extract of the plant Hypericum perforatum and optionally in addition, one or more pharmaceutically acceptable inactive components, selected from, carriers, coatings, diluents and adjuvants.
    Type: Grant
    Filed: December 15, 1997
    Date of Patent: May 2, 2000
    Inventors: David Lavie, Anne Steinbeck-Klose
  • Preparation of hypericin
    Patent number: 5120412
    Abstract: A process for preparing hypericin comprises oxidative dimerization of emodin anthrone and conversion of the intermediate protohypericin to hypericin by irradiation with visible light.
    Type: Grant
    Filed: November 9, 1990
    Date of Patent: June 9, 1992
    Assignee: Yeda Research and Development Co. Ltd.
    Inventors: Yehuda Mazur, Harald Bock, David Lavie
  • Antiviral aerosol compositions and pressurized containers containing same
    Patent number: 5049589
    Abstract: The invention relates to antiviral compositions of matter containing as active ingredient hypericin or pseudohypericin. The novel compositions are of special use in the treatment of, and alleviation of symptons of various diseases caused by viruses such as vesicular stomatitis, influenza, herpes simplex, HSV-1 and HSV-2. The mode of activity seems to be by inhibition of RNA synthesis and interfering with virus replication. The pharmaceutical compositions can be applied by a variety of routes. Topical applications have proved to be effective against a variety of viral afflictions.
    Type: Grant
    Filed: December 19, 1989
    Date of Patent: September 17, 1991
    Assignee: Yeda Research and Development Company, Ltd.
    Inventors: David Lavie, Michel Revel, Dalia Rotman, Vincent Vande Velde
  • Antiviral compositions containing aromatic polycyclic diones and method for treating retrovirus infections
    Patent number: 5047435
    Abstract: Pharmaceutical formulations comprising aromatic polycyclic dione compounds useful for treating mammals suffering from diseases caused by retroviruses are disclosed herein. A method for treating mammals suffering from retrovirus infections is also disclosed.
    Type: Grant
    Filed: March 27, 1989
    Date of Patent: September 10, 1991
    Assignees: New York University, Yeda Research and Development Company, Ltd.
    Inventors: David Lavie, Daniel Meruelo, Gad Lavie, Michel Revel, Vincent Vande Velde, Dalia Rotman
  • Antiviral compositions
    Patent number: 4898891
    Abstract: The invention relates to antiviral compositions of matter containing as active ingredient hypericin or pseudohypericin. The novel compositions are of special use in the treatment of, and alleviation of symptoms of various diseases caused by viruses such as vesicular stomatitis, influenza, herpes simplex, HSV-1 and HSV-2. The mode of activity seems to be by inhibition of RNA synthesis and interfering with virus replication. The pharmaceutical compositions can be applied by a variety of routes. Topical applications have proved to be effective against a variety of viral afflictions.
    Type: Grant
    Filed: August 7, 1987
    Date of Patent: February 6, 1990
    Assignee: Yeda Research and Development Company Ltd.
    Inventors: David Lavie, Michel Revel, Dalia Rotman, Vincent V. Velde