Abstract: Disclosed herein is a phosphorus modified UZM-35 zeolite, methods of its preparation, and methods of its use in hydrocarbon conversion processes, e.g., as part of a catalyst component and/or as part of a catalyst composition. Catalyst components with phosphorus modified UZM-35, their methods of preparation, and their methods of use suitable for petroleum refining applications (e.g., hydrocarbon conversion processes such as fluid catalytic cracking and hydrocracking) are described herein. Also disclosed herein are catalyst compositions, which include phosphorus modified UZM-35 and catalyst components thereof along with at least one additional catalyst component. Methods of preparing and methods of using such catalyst compositions are also encompassed by the instant disclosure.

Abstract: Methods for identifying and classifying differences between biological samples are based on replication timing (RT) data. By comparing RT data for a test sample(s) to RT data for already characterized samples, one can identify differences and profile any new cell type or disease. These new methods allow for the detection of all the changes between distinct samples, many of which would escape detection by previous methods that discard any features showing any intra-sample variation.

Abstract: Methods for identifying and classifying differences between biological samples are based on replication timing (RT) data. By comparing RT data for a test sample(s) to RT data for already characterized samples, one can identify differences and profile any new cell type or disease. These new methods allow for the detection of all the changes between distinct samples, many of which would escape detection by previous methods that discard any features showing any intra-sample variation.

Abstract: Methods for identifying and/or distinguishing a homogeneous population of cells based on their replication domain timing profile using high resolution genomic arrays or sequencing procedures are provided. These methods may be used to compare the replication timing profile for a population of cells to another replication timing profile(s), a replication timing fingerprint, and/or one or more informative segments of a replication timing fingerprint, which may be simultaneously or previously determined and/or contained in a database, to determine whether there is a match between them. Based on such information, the identity of the population of cells may be determined, or the identity of the population of cells may be distinguished from other populations of cells or cell types. Methods for determining a replication timing fingerprint for particular cell types are also provided.

Abstract: Mass customization of articles with a customized composite or dimensional image created from one or more custom images, such as photographs, text, and the like. The customized composite image is automatically generated by interlacing, or otherwise combining, the one or more custom or personalized images, and is automatically placed or imposed in a digital template to form a print ready file. The print file is then digitally printed on a substrate and a lens is married thereto such that the composite image is viewable through the lens. Alternatively, the print ready file, or at least the customized composite image, is printed directly on the back of a lens such that the composite image is viewable through the lens.

Abstract: A method for determining a replication timing footprint comprises the following steps: (a) selecting a set of chosen regions of the replication timing profile of a chromosome of an individual, (b) choosing a set of selected regions from the set of chosen regions to form a set of selected regions and a set of unused regions, (c) conducting a iterative algorithm on the set of selected regions until a domain number for the set of selected regions has decreased to a predetermined minimum, (d) determining a replication timing footprint based the set of selected regions after step (c) has been conducted, and (e) displaying the replication timing footprint to a user.

Abstract: Mass customization of articles with a customized composite or dimensional image created from one or more custom images, such as photographs, text, and the like. The customized composite image is automatically generated by interlacing, or otherwise combining, the one or more custom or personalized images, and is automatically placed or imposed in a digital template to form a print ready file. The print file is then digitally printed on a substrate and a lens is married thereto such that the composite image is viewable through the lens. Alternatively, the print ready file, or at least the customized composite image, is printed directly on the back of a lens such that the composite image is viewable through the lens.

Abstract: Provided herein is a capture library for target enrichment of sequences of interest from a genome DNA sample. The capture library comprises a plurality of capture oligos tiling a plurality of capture regions evenly-spaced along a genome. Each two adjacent capture regions of the plurality capture regions are separated by a spacing of about 6 to about 14 kilobases in length. The plurality of capture regions has a size of about 150 base pairs in length. Further, each capture oligo of the plurality of capture oligos comprises average 70 nucleotides in length. The capture libraries are suitable for enriching about 150 base pairs region approximately every 10 kilobases in a genome DNA. This capture library can be used to measure replication timing and copy number variation in human pediatric acute lymphocytic leukemia samples, and is also broadly applicable to any CNV application.

Abstract: Methods for identifying and/or distinguishing a homogeneous population of cells based on their replication domain timing profile using high resolution genomic arrays or sequencing procedures are provided. These methods may be used to compare the replication timing profile for a population of cells to another replication timing profile(s), a replication timing fingerprint, and/or one or more informative segments of a replication timing fingerprint, which may be simultaneously or previously determined and/or contained in a database, to determine whether there is a match between them. Based on such information, the identity of the population of cells may be determined, or the identity of the population of cells may be distinguished from other populations of cells or cell types. Methods for determining a replication timing fingerprint for particular cell types are also provided.

Abstract: A method for determining a replication timing footprint comprises the following steps: (a) selecting a set of chosen regions of the replication timing profile of a chromosome of an individual, (b) choosing a set of selected regions from the set of chosen regions to form a set of selected regions and a set of unused regions, (c) conducting a iterative algorithm on the set of selected regions until a domain number for the set of selected regions has decreased to a predetermined minimum, (d) determining a replication timing footprint based the set of selected regions after step (c) has been conducted, and (e) displaying the replication timing footprint to a user.

Abstract: Methods for identifying and/or distinguishing a homogeneous population of cells based on their replication domain timing profile using high resolution genomic arrays or sequencing procedures are provided. These methods may be used to compare the replication timing profile for a population of cells to another replication timing profile(s), a replication timing fingerprint, and/or one or more informative segments of a replication timing fingerprint, which may be simultaneously or previously determined and/or contained in a database, to determine whether there is a match between them. Based on such information, the identity of the population of cells may be determined, or the identity of the population of cells may be distinguished from other populations of cells or cell types. Methods for determining a replication timing fingerprint for particular cell types are also provided.

Abstract: Described is a method for determining that a population of cells are a specific type of leukemic cell based on the replication timing fingerprint for the population of cells.

Abstract: Described is a method for determining that a population of cells are a specific type of leukemic cell based on the replication timing fingerprint for the population of cells.

Abstract: Methods for identifying and/or distinguishing a homogeneous population of cells based on their replication domain timing profile using high resolution genomic arrays or sequencing procedures are provided. These methods may be used to compare the replication timing profile for a population of cells to another replication timing profile(s), a replication timing fingerprint, and/or one or more informative segments of a replication timing fingerprint, which may be simultaneously or previously determined and/or contained in a database, to determine whether there is a match between them. Based on such information, the identity of the population of cells may be determined, or the identity of the population of cells may be distinguished from other populations of cells or cell types. Methods for determining a replication timing fingerprint for particular cell types are also provided.

Abstract: Mass customization of articles with a customized composite or dimensional image created from one or more custom images, such as photographs, text, and the like. The customized composite image is automatically generated by interlacing, or otherwise combining, the one or more custom or personalized images, and is automatically placed or imposed in a digital template to form a print ready file. The print file is then digitally printed on a substrate and a lens is married thereto such that the composite image is viewable through the lens. Alternatively, the print ready file, or at least the customized composite image, is printed directly on the back of a lens such that the composite image is viewable through the lens.

Abstract: Methods for identifying and/or distinguishing a homogeneous population of cells based on their replication domain timing profile using high resolution genomic arrays or sequencing procedures are provided. These methods may be used to compare the replication timing profile for a population of cells to another replication timing profile(s), a replication timing fingerprint, and/or one or more informative segments of a replication timing fingerprint, which may be simultaneously or previously determined and/or contained in a database, to determine whether there is a match between them. Based on such information, the identity of the population of cells may be determined, or the identity of the population of cells may be distinguished from other populations of cells or cell types. Methods for determining a replication timing fingerprint for particular cell types are also provided.

Abstract: A process for treating contaminants present in subsurface source zones comprises in situ admixing of contaminated media, chemical oxidants and stabilizing agents using known soil-mixing techniques. A grout for treating contaminants present in soil comprises chemical oxidants and stabilizing agents.

Abstract: A pad grid array semiconductor package (28) provides interconnect pads (30) of equal pad area and matrixed locations, placing an interconnect pad in a fixed location relative to an adjacent interconnect pad. Die pad (48) and interconnect pads (30) are formed from an etched, or otherwise formed, conductive lead frame. Die pad (48) is in full contact with semiconductor die (50), providing pad grid array interconnect pads (30) in electrically conductive contact to semiconductor die (50). Interconnect pad (58) is removed in an alternate configuration to provide spacial orientation of pad grid array package (56).

Abstract: An electronic component (10) has an electrically insulating substrate (20) that is encapsulated with an electrically conductive material (15) to provide thermal dissipation for the electronic component (10). The electrically insulating substrate (20) has cavities (21-24) that are either completely filled with an electrically conductive material (15) or are partially filled to provide recesses (26-27) for electronic devices (30,31). The electronic devices (30,31) are electrically coupled to the leads (60-63) of the electronic component (10) using either wire bonds (70) or metallic depositions (55-57).

Abstract: A monolithic light-activated line-operable zero-crossing switch and method of making the same. The device comprises anti-parallel thyristors, each of whose gates is shunted by a field effect transistor. Each device may also be shunted by a resistor to reduce the overall sensitivity. The method of making the device contemplates surrounding the field effect transistor gate electrode and an internal shunt electrode by the primary metallization which forms the contact to the two main terminals of the device.