Abstract: Provided herein are de novo binding domain containing polypeptides (DBDpp) that specifically bind a target of interest. Nucleic acids encoding the DBDpp, and vectors and host cells containing the nucleic acids are also provided. Libraries of DBDpp, methods of producing and screening such libraries and the DBDpp identified from such libraries and screens are also encompassed. Methods of making and using the DBDpp are additionally provided. Such uses include, without limitation, affinity purification, and diagnostic and therapeutic applications.

Abstract: Compositions containing multivalent and monovalent multispecific complexes having scaffolds such as antibodies that support such binding functionalities are described. The use of and methods of compositions containing multivalent and monovalent multispecific complexes having scaffolds, such as antibodies, that support such binding functionalities are also described.

Abstract: EGFR-binding modular recognition domains (MRDs) and complexes containing such MRDs linked to antibodies are described. The use of such MRDs and complexes are also described.

Abstract: Complexes containing one or more modular recognition domains (MRDs) and MRDs attached to scaffolds including antibodies are described. The manufacture of these complexes are the use of these complexes to treat and diagnose diseases and disorders are also described.

Abstract: Provided herein are de novo binding domain containing polypeptides (DBDpp) that specifically bind a target of interest. Nucleic acids encoding the DBDpp, and vectors and host cells containing the nucleic acids are also provided. Libraries of DBDpp, methods of producing and screening such libraries and the DBDpp identified from such libraries and screens are also encompassed. Methods of making and using the DBDpp are additionally provided. Such uses include, without limitation, affinity purification, and diagnostic and therapeutic applications.

Abstract: Provided herein are de novo binding domain containing polypeptides (DBDpp) that specifically bind a target of interest. Nucleic acids encoding the DBDpp, and vectors and host cells containing the nucleic acids are also provided. Libraries of DBDpp, methods of producing and screening such libraries and the DBDpp identified from such libraries and screens are also encompassed. Methods of making and using the DBDpp are additionally provided. Such uses include, without limitation, affinity purification, and diagnostic and therapeutic applications.

Abstract: Complexes containing one or more modular recognition domains (MRDs) and MRDs attached to scaffolds including antibodies are described. The manufacture of these complexes are the use of these complexes to treat and diagnose diseases and disorders are also described.

Abstract: Embodiments of the present invention enable the extraction, classification, storage, and supplementation of presentation video. A media system receives a video signal carrying presentation video. The media system processes the video signal and generates images for slides of the presentation. The media system then extracts text from the images and uses the text and other characteristics to classify the images and store them in a database. Additionally, the system enables viewers of the presentation to provide feedback on the presentation, which can be used to supplement the presentation.

Abstract: Compositions containing multivalent and monovalent multispecific complexes having scaffolds such as antibodies that support such binding functionalities are described. The use of and methods of compositions containing multivalent and monovalent multispecific complexes having scaffolds, such as antibodies, that support such binding functionalities are also described.

Abstract: Complexes containing one or more modular recognition domains (MRDs) and MRDs attached to scaffolds including antibodies are described. The manufacture of these complexes are the use of these complexes to treat and diagnose diseases and disorders are also described.

Abstract: The present invention provides novel therapeutics and methods of treatment for diseases associated with activation of the advanced glycatio? endproducts receptor (RAGE).

Abstract: Complexes containing one or more modular recognition domains (MRDs) and MRDs attached to scaffolds including antibodies are described. The manufacture of these complexes are the use of these complexes to treat and diagnose diseases and disorders are also described.

Abstract: Compositions containing multivalent and monovalent multispecific complexes having scaffolds such as antibodies that support such binding functionalities are described. The use of and methods of compositions containing multivalent and monovalent multispecific complexes having scaffolds, such as antibodies, that support such binding functionalities are also described.

Abstract: The present invention provides novel therapeutics and methods of treatment for diseases associated with activation of the advanced glycation endproducts receptor (RAGE).

Abstract: Compositions containing multivalent and monovalent multispecific complexes having scaffolds such as antibodies that support such binding functionalities are described. The use of and methods of compositions containing multivalent and monovalent multispecific complexes having scaffolds, such as antibodies, that support such binding functionalities are also described.

Abstract: The present invention provides novel therapeutics and methods of treatment for diseases associated with activation of the advanced glycatio? endproducts receptor (RAGE).

Abstract: Capturing a sequence of images of a multi-page printed document is performed by a handheld device, such as a Smartphone. The device has one or more processors, memory, and a digital image sensor. The device monitors preview images of a first printed page of the multi-page printed document, where the preview images are generated by the digital image sensor. Without user indication of when to capture an image, the device captures a still image of the first printed page when a first quality metric of the preview images exceeds a first quality threshold. The device repeats the monitoring and capturing of additional pages until receiving indication from the user that capturing images is complete. In response to receiving indication from the user that capturing images is complete, the device concatenates the captured still images into a single digital document and stores the single digital document.

Abstract: Example embodiments described herein are directed to utilizing image matching technology to allow people to use their mobile device to setup scan workflows (or “Scan Flows”) in advance of a future scanning operation. Using an application on a mobile device, the user takes a photo of the first page of a document that he/she will scan at some later time and associates the image of the document with a simple workflow (e.g., where to store the document once the document has been scanned). Additional workflow actions may include automatic document sharing and notification, automatic document segmentation, and automatic document cropping.

Abstract: Capturing a sequence of images of a multi-page printed document is performed by a handheld device, such as a Smartphone. The device has one or more processors, memory, and a digital image sensor. The device monitors preview images of a first printed page of the multi-page printed document, where the preview images are generated by the digital image sensor. Without user indication of when to capture an image, the device captures a still image of the first printed page when a first quality metric of the preview images exceeds a first quality threshold. The device repeats the monitoring and capturing of additional pages until receiving indication from the user that capturing images is complete. In response to receiving indication from the user that capturing images is complete, the device concatenates the captured still images into a single digital document and stores the single digital document.

Abstract: Monovalent and multivalent multispecific complexes including ELP-MRD fusion proteins containing one or more modular recognition domains (MRDs) that bind target antigens are described. The use of these monovalent and multivalent multispecific complexes (e.g., ELP-MRD fusion proteins) in diagnostic, prognostic, and therapeutic applications and methods of making these complexes are also described.