Patents by Inventor David M. Nanus

David M. Nanus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Endopeptidase/anti-PSMA antibody fusion proteins for treatment of cancer
    Publication number: 20030007974
    Abstract: A fusion protein for treatment of prostate cancer and other cancers which includes an endopeptidase bound to a monoclonal antibody, or an antigen binding portion thereof, specific for prostate specific membrane antigen (PSMA)expressed either on the tumor cell surface or on the surface of epithelial cells within the tumor. The invention also features pharmaceutical compositions comprising such fusion proteins as well as methods of manufacture and treatment with such fusion proteins.
    Type: Application
    Filed: May 30, 2002
    Publication date: January 9, 2003
    Inventors: David M. Nanus, Shen Ruoqian, Neil Bander
  • Method to detect sensitivity to alpha-interferon therapy
    Patent number: 5145773
    Abstract: This invention provides a method of detecting sensitivity to alpha-interferon therapy which comprises contacting a sample with a monoclonal antibody under conditions so as to form an antibody-antigen complex, detecting the complex so formed, and thereby detecting sensitivity to alpha-interferon.
    Type: Grant
    Filed: May 25, 1989
    Date of Patent: September 8, 1992
    Assignee: Sloan-Kettering Institute for Cancer Research
    Inventors: Anthony P. Albino, David M. Nanus, Neil H. Bander, Lawrence M. Pfeffer