Abstract: A surgical instrument, has an end effector that includes an ultrasonic blade, and a clamp arm that moves relative to the ultrasonic blade from an opened position toward an intermediate position and a closed position. The clamp arm is offset from the ultrasonic blade to define a predetermined gap in the intermediate position between the opened position and the closed position. A clamp arm actuator connects to the clamp arm and moves from an opened configuration to a closed configuration to direct the clamp arm from the opened position toward the intermediate position and the closed position. A spacer connects with the clamp arm to inhibit movement of the clamp arm from the intermediate position toward the closed position for maintaining the predetermined gap between the clamp arm and the ultrasonic blade.

Abstract: The present disclosure provides human interleukin 4 receptor alpha antibody glucocorticoid receptor agonist conjugates and methods of using the conjugates for the treatment of inflammatory diseases, such as type 2 inflammatory diseases.

Abstract: A cursor control device has an input signal reader adapted to read an input signal created by movement of a surface there across, and a signal processing component adapted to process the input signal from the reader and to communicate a corresponding signal to a controller that is directly proportional to the input signal. The device remains in a substantially constant position relative to an active hand of a person when the person is using the active hand to operate a second device.

Abstract: Noise suppression and particle separation apparatus for flows of high pressure, high velocity, particle-laden, gaseous fluid, such as geothermal steam, comprises a gaseous fluid conduit that has axially installed around its discharge end a larger diameter, cylindrical inner expansion chamber having a number of flow-dividing fluid discharge openings at which fluid flow diffusing elements are connected for receiving and diffusing the flow of gaseous fluid from the apertures. A still-larger diameter, cylindrical noise suppression chamber is axially mounted around the inner chamber and flow diffusing elements. The diffusion elements increase the fluid flow noise frequency range and sound deadening material installed in the outer chamber absorbs noise in this higher frequency range so that the venting fluid noise level outside the apparatus is no more than about 95 dB.