Patents by Inventor David M. Smalley

David M. Smalley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Galectin-3-Binding Protein as a Biomarker of Cardiovascular Disease
    Publication number: 20100055723
    Abstract: The present invention provides compositions and methods for using biomarkers to diagnose and monitor cardiovascular associated diseases and disorders. More specifically, the present invention provides Galectin-3-binding protein as a biomarker for disease.
    Type: Application
    Filed: January 23, 2008
    Publication date: March 4, 2010
    Applicant: UNIVERSITY OF VIRGINIA PATENT FOUNDATION
    Inventors: David M. Smalley, Christian A. Gleissner, Klaus F. Ley
  • PROTEIN-BASED BIOMARKERS FOR ABDOMINAL AORTIC ANEURYSM
    Publication number: 20090093005
    Abstract: The present invention encompasses compositions and methods useful for diagnosing subjects with abdominal aortic aneurysms. The invention relates to the use of protein biomarkers whose levels are different in subjects with abdominal aortic aneurysms relative to normal subjects.
    Type: Application
    Filed: October 3, 2008
    Publication date: April 9, 2009
    Applicant: UNIVERSITY OF VIRGINIA PATENT FOUNDATION
    Inventors: David M. Smalley, Nancy L. Harthun, Klaus F. Ley, Ian J. Sarembock, Kristina Little
  • Methods for identifying and analyzing biomarkers from plasma-derived microparticles
    Patent number: 7462489
    Abstract: The present invention provides methods for identifying candidate biomarkers in the plasma microparticle proteome. It also provides methods for isolating, identifying, and analyzing microparticles derived from plasma, particularly platelet-poor plasma.
    Type: Grant
    Filed: November 5, 2007
    Date of Patent: December 9, 2008
    Inventors: Klaus F. Ley, David M. Smalley
  • METHODS FOR IDENTIFYING AND ANALYZING BIOMARKERS FROM PLASMA-DERIVED MICROPARTICLES
    Publication number: 20080171312
    Abstract: The present invention provides methods for identifying candidate biomarkers in the plasma microparticle proteome. It also provides methods for isolating, identifying, and analyzing microparticles derived from plasma, particularly platelet-poor plasma.
    Type: Application
    Filed: November 5, 2007
    Publication date: July 17, 2008
    Applicant: MICROPARTICLE PROTEOMICS, LLC
    Inventors: Klaus F. Ley, David M. Smalley