Abstract: An integrated window and wall system for buildings, particularly industrial and commercial buildings, comprising ladder-like horizontally extending outer and inner metal members which clamp onto the bottom and top portions of insulating wall panels, and clamp onto window glazing units mounted in the openings of said ladder-like members. Extending across both longitudinal sides of the ladder-like metal members are substantially horizontal gutter and reinforcing flanges for draining water from the upper wall panels and from the lower edge of the window glazing units. The water drains through sponge-like baffles and through weep holes spaced along the outer longitudinal members. The exposed inner metal members are thermally isolated from the outer metal members. Glazing beads are provided for adjustably clamping between said outer and inner metal members, either single or double pane glass windows.