Patents by Inventor David Ma
David Ma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240153229Abstract: Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data.Type: ApplicationFiled: May 1, 2023Publication date: May 9, 2024Applicant: ELUCID BIOIMAGING INC.Inventors: Andrew J. BUCKLER, Kjell JOHNSON, Xiaonan MA, Keith A. MOULTON, Mark A. BUCKLER, Vladimir VALTCHINOV, David S. PAIK
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Patent number: 11976497Abstract: A drawer lock assembly is provided including a housing having a front face and a rear face; a barrel having a first end extending perpendicularly from the front face of the housing and a second end extending through the rear face of the housing; a locking actuation member disposed through the first end of the barrel; a driver disposed through the second end of the barrel to engage the locking actuation member; a bolt including a first member offset from a second member in a parallel relationship, the first member includes a slot configured to receive a cam of the driver; and an endplate configured to retain the driver and bolt in the housing, the endplate including a channel configured to receive the second member of the bolt, wherein upon actuation of the locking actuation member, the second member extends beyond the housing to engage a recess of a structure.Type: GrantFiled: December 22, 2021Date of Patent: May 7, 2024Assignee: Innovation Lock, LLCInventors: William H. Bullwinkel, Robert Ludwig, David R. Wachsman, Alvin Ma
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Patent number: 11974993Abstract: Provided herein are solution formulations of CX-011 and related methods for making solution formulations of CX-011. Also provided are methods of treating an inflammatory disorder, such as osteoarthritis, or cancer in a subject in need thereof by administering an effective amount of the solution formulations of CX-011.Type: GrantFiled: February 22, 2022Date of Patent: May 7, 2024Assignee: City of HopeInventors: Yuelong Ma, Rajiv Nallu, David Horne
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Patent number: 11974845Abstract: Systems and methods are disclosed which provide for a “factory-calibrated” sensor. In doing so, the systems and methods include predictive prospective modeling of sensor behavior, and also include predictive modeling of physiology. With these two correction factors, a consistent determination of sensitivity can be achieved, thus achieving factory calibration.Type: GrantFiled: July 6, 2021Date of Patent: May 7, 2024Assignee: Dexcom, Inc.Inventors: Rui Ma, Naresh C. Bhavaraju, Thomas Stuart Hamilton, Jonathan Hughes, Jeff Jackson, David I-Chun Lee, Peter C. Simpson, Stephen J. Vanslyke
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Publication number: 20240146435Abstract: A passive optical network system having a node that is optically coupled to optical line terminals (OLTs), and that is optically coupled to optical network units (ONUs). The node includes at least one fiber link module (FLM), each FLM including an upstream multiplex conversion device (MCD), and a downstream MCD. The upstream MCD receives an upstream optical signal from the ONUs, converts the upstream optical signal to an upstream electrical signal, and transmits a regenerated upstream optical signal to the OLTs. The downstream MCD receives a downstream optical signal from the OLTs, converts the downstream optical signal to a downstream electrical signal, and transmits a regenerated downstream optical signal to the ONUs.Type: ApplicationFiled: September 27, 2023Publication date: May 2, 2024Applicant: ARRIS Enterprises LLCInventors: David B. Bowler, Xinfa Ma
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Publication number: 20240132823Abstract: Photoreceptor scaffolds that can be used for transplantation of organized photoreceptor tissue, with or without retinal pigment epithelial cells, which may improve grafted cell survival, integration, and functional visual rescue are disclosed herein. The scaffolds include a cell support layer having at least one honeycomb-shaped reservoir fluidly connected to a plurality of through-holes and at least one cell in the at least one honeycomb-shaped reservoir.Type: ApplicationFiled: October 11, 2020Publication date: April 25, 2024Inventors: Zhenqiang Ma, Inkyu Lee, Juhwan Lee, Michael Phillips, David Gamm, Shaoqin Gong
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Patent number: 11952636Abstract: The disclosure relates generally to molecular diagnostic devices configured to amplifying a single nucleotide polymorphism (SNP) locus and discriminate between two or more allelic variants of the SNP, indicating presence or absence of a target allele. In some embodiments, the molecular diagnostic devices are capable of detecting, at point-of-care, SNPs associated with resistance or susceptibility to antibiotic treatment of organism infections. In other aspects, the disclosure provides methods of treatment for disease or disorders (e.g. organism infections) where treatment is guided by presence or absence of an allele at a SNP locus as determined by such molecular diagnostic devices.Type: GrantFiled: May 6, 2022Date of Patent: April 9, 2024Assignee: Visby Medical, Inc.Inventors: Brian Ciopyk, Paul Dentinger, Teresa Abraham, Brandon Ma, Kamal Kajouke, Mackenzie Hunt, Austin Phung, Karl Guegler, David Swenson, Anna H. Postlethwaite
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Patent number: 11948187Abstract: A leasing AI platform receives a message pertaining to leasing a real estate unit, generates a token matrix representing at least a portion of the message, and provide the token matrix as an input to a trained machine learning model. An output of the trained machine learning model comprises an indication of a first category associated with the at least the portion of the message. The leasing AI platform identifies one or more actions associated with the first category, the actions pertaining to leasing the real estate unit, and automatically executes the one or more actions without human involvement in response to receiving the message.Type: GrantFiled: March 22, 2023Date of Patent: April 2, 2024Assignee: APPFOLIO, INC.Inventors: Elliott Burris, Daniel Posch, Kyle Triplett, David Ma, Robert Ryan, John Rothfels
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Patent number: 11938848Abstract: A child restraint system is provided and configured to be installed on a vehicle seat to support a child. The child restraint system includes a main body, a reclining foot and an adjusting foot. The main body includes a seat portion and a backrest portion. The reclining foot is pivotably coupled to the main body. The adjusting foot is pivotably coupled to the main body or the reclining foot. The adjusting foot is pivotable between a forward position and a rearward position. No matter when the child restraint system is in a rearward-facing direction or a forward-facing direction, the child restraint system can be supported stably on the vehicle seat, and a recline position of the child restraint system can be adjusted in a wide adjustment range by pivoting of the reclining foot. Therefore, the child restraint system is convenient to use.Type: GrantFiled: November 3, 2021Date of Patent: March 26, 2024Assignee: WONDERLAND SWITZERLAND AGInventors: Andrew Ma, David A Lehman, Kyle S Mason
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Publication number: 20240098969Abstract: Systems, methods and apparatus are provided for an array of vertically stacked memory cells having horizontally oriented access devices and storage nodes formed in tiers. And, more particularly, to multiple, alternating silicon germanium (SiGe) and single crystalline silicon (Si) in different thicknesses to form tiers in which to form the horizontal access devices in vertical three-dimensional (3D) memory. The horizontally oriented access devices can have a first source/drain regions and a second source drain regions separated by single crystalline silicon (Si) channel regions. The single crystalline silicon (Si) channel regions can include a dielectric material to provide support structure to the single crystalline channel regions when forming the horizontal access devices in vertical three-dimensional (3D) memory. Horizontally oriented access lines can connect to gate structures opposing the channel regions. Vertical digit lines coupled to the first source/drain regions.Type: ApplicationFiled: September 15, 2022Publication date: March 21, 2024Inventors: David K. Hwang, Yoshitaka Nakamura, Scott E. Sills, Si-Woo Lee, Yuanzhi Ma, Glen H. Walters
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Publication number: 20240098970Abstract: Systems, methods and apparatus are provided for an array of vertically stacked memory cells having horizontally oriented access devices and storage nodes. The horizontally oriented access devices having a first source/drain regions and a second source drain regions separated by silicon (Si) channel regions. A digit line having a global digit line (GDL) contact is formed in a trench adjacent to the first source/drain regions. In one example, the digit line is electrically isolated from a neighboring digit line at the bottom of the trench. In another example, the digit line is formed continuously along a bottom surface of trench to form shared digit lines between horizontal access devices, in two separate arrays, on opposing second vertical surfaces. The memory cells have horizontally oriented storage nodes coupled to the second source/drain regions and vertical digit lines coupled to the first source/drain regions.Type: ApplicationFiled: September 16, 2022Publication date: March 21, 2024Inventors: Scott E. Sills, Si-Woo Lee, David K. Hwang, Yoshitaka Nakamura, Yuanzhi Ma, Glen H. Walters
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Patent number: 11932606Abstract: This invention provides, among other things, compounds useful for treating diseases such as fibrosis and/or cancer, pharmaceutical formulations containing such compounds, as well as combinations of these compounds with at least one additional therapeutic agent.Type: GrantFiled: July 31, 2018Date of Patent: March 19, 2024Assignee: The Regents of the University of CaliforniaInventors: David M. Jablons, Wei Xu, Liang You, Shu Liu, Shendong Yuan, Sunghoon Ma, Morrison Mac
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Publication number: 20240083913Abstract: The disclosure provides compounds of Formula (I) or a pharmaceutically acceptable salt thereof, wherein W1, W2, Y, Z, M, L, CY, Cz, R1, R2, R3, R4, R2a, Ry, Rz, and the subscripts m, n, q, and r are as described herein. The compounds or their pharmaceutically acceptable salts can inhibit the G12C mutant of Kirsten rat sarcoma (KRAS) protein and are expected to have utility as therapeutic agents, for example, for treating cancer. The disclosure also provides pharmaceutical compositions which comprise compounds of Formula (I) or pharmaceutically acceptable salts thereof. The disclosure also relates to methods for use of the compounds or their pharmaceutically acceptable salts in the therapy and prophylaxis of cancer and for preparing pharmaceuticals for this purpose.Type: ApplicationFiled: May 3, 2023Publication date: March 14, 2024Inventors: Indu Bharathan, Symon Gathiaka, Yongxin Han, Xiaoshen Ma, Ryan D. Otte, David L. Sloman, Thomas H. Graham, Timothy Henderson, Elisabeth Hennessy, Anandan Palani
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Publication number: 20240078672Abstract: Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data.Type: ApplicationFiled: November 8, 2023Publication date: March 7, 2024Applicant: ELUCID BIOIMAGING INC.Inventors: Andrew J. BUCKLER, Kjell JOHNSON, Xiaonan MA, Keith A. MOULTON, David S. PAIK
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Publication number: 20240078673Abstract: Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data.Type: ApplicationFiled: November 8, 2023Publication date: March 7, 2024Applicant: ELUCID BIOIMAGING INC.Inventors: Andrew J. BUCKLER, Kjell JOHNSON, Xiaonan MA, Keith A. MOULTON, David S. PAIK
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Publication number: 20240078671Abstract: Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data.Type: ApplicationFiled: November 8, 2023Publication date: March 7, 2024Applicant: ELUCID BIOIMAGING INC.Inventors: Andrew J. BUCKLER, Kjell JOHNSON, Xiaonan MA, Keith A. MOULTON, David S. PAIK
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Patent number: 11918582Abstract: Disclosed herein are pyrazole pyrimidine compounds that modulate and/or inhibit hematopoietic progenitor kinase 1, as well as methods of making such compounds and therapeutic methods of using same.Type: GrantFiled: March 14, 2022Date of Patent: March 5, 2024Assignee: RAPT Therapeutics, Inc.Inventors: Cyril Bucher, Adrian Dukes, Blanca Gomez, Hannah Haley, Dennis Hu, Jeffrey J. Jackson, Michelle Yoo Min Ko, Paul Leger, Anqi Ma, Andrew A. Ng, Daniel Poon, Omar Robles, Anton Shakhmin, Grant Shibuya, Parcharee Tivitmahaisoon, Vi-Anh Vu, David J. Wustrow, Mikhail Zibinsky
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Publication number: 20240069268Abstract: A multiview backlight, multiview display, and method of multiview backlight operation include reflective multibeam elements configured to provide emitted light having directional light beams with directions corresponding to view directions of a multiview image. The multiview backlight includes a light guide configured to guide light and an array of the reflective multibeam elements. Each reflective multibeam element includes a plurality of reflective sub-elements and is configured to reflectively scatter out a portion of the guided light as the emitted light. The multiview display includes the multiview backlight and an array of light valves to modulate the directional light beams to provide the multiview image. Each reflective sub-element protrudes from a guiding surface of the light guide by a respective protrusion distance. At least some of the protrusion distances can vary as a function of distance along a length of the light guide.Type: ApplicationFiled: October 25, 2023Publication date: February 29, 2024Inventors: David A. Fattal, Thomas Hoekman, Colton Bukowsky, Ming Ma
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Publication number: 20240074141Abstract: Methods and devices for a lateral three-dimensional memory device, are described herein. One method includes forming a thin film transistor including a first thermal process having a first range of temperatures, forming a capacitor bottom electrode of a capacitor structure including a second thermal process having a second range of temperature, wherein a maximum temperature in the second range of temperatures is less than a maximum temperature in the first range of temperatures, forming a CMOS structure including a third thermal process having a third range of temperatures, wherein a maximum temperature in the third range of temperatures is less than a maximum temperature in the second range of temperatures, and forming at least one other part of the capacitor structure.Type: ApplicationFiled: August 24, 2022Publication date: February 29, 2024Inventors: Yoshitaka Nakamura, Yuanzhi Ma, Scott E. Sills, Si-Woo Lee, David K. Hwang
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Patent number: 11912985Abstract: The present disclosure provides systems, compositions, and methods for simultaneously editing both strands of a double-stranded DNA sequence at a target site to be edited. Further provided herein are pharmaceutical compositions, polynucleotides, vectors, cells, and kits for simultaneously editing both strands of a double-stranded DNA sequence.Type: GrantFiled: November 7, 2022Date of Patent: February 27, 2024Assignees: The Broad Institute, Inc., President and Fellows of Harvard CollegeInventors: David R. Liu, Andrew Vito Anzalone, Jonathan Ma Levy, Xin Gao, Christopher J. Podracky