Abstract: Provided herein are methods, compositions and uses involving T cell therapies, such as adoptive T cell therapy, and an inhibitor of a Diacylglycerol kinase (DGK). The provided methods, compositions and uses include those involving the administration or use of one or more DGK inhibitors (DGKi) in a combination therapy with a T cell therapy, such as a genetically engineered T cell therapy involving cells engineered with a recombinant receptor, such as chimeric antigen receptor (CAR) or T cell receptor (TCR).

Abstract: A method for monitoring a failure in a high-voltage circuit of a vehicle includes obtaining a supply voltage of a high-voltage power supply device; obtaining component voltage(s) on one or more high-voltage components powered by the high-voltage power supply device; comparing the supply voltage with each component voltage; and determining that a failure exists in the high-voltage circuit when the voltage difference between the supply voltage and any one of the component voltage(s) exceeds a predetermined threshold. Also disclosed are a computer readable storage medium, an equipment for monitoring a failure in a high-voltage circuit of a vehicle, a high-voltage circuit system for a vehicle, and a vehicle comprising the high-voltage circuit system.

Abstract: The present invention relates to a method for increasing the efficiency of an energy transfer device (100) with which electrical energy is converted contactlessly into electrical energy with the aid of a magnetic field in order to electrically excite a rotor of an electrical machine, comprising the step of: arranging an additional electrically conductive material layer (13) on at least one active part (12, 19, 35, 45) of the energy transfer device (100), wherein an active part of the energy transfer device (100) is a part of the energy transfer device (100) which is at least partially exposed to the magnetic field used for energy transfer, and wherein the electrical conductivity of the additional material layer (13) is greater than the electrical conductivity of the at least one active part (12, 19, 35, 45). Moreover, the invention relates to an energy transfer device (100) and to a use of an electrically conductive material.

Abstract: A method for detecting a faulty voltage sensor of a group of n?3 voltage sensors of controllers in an onboard electrical system of a vehicle, wherein (a) voltage measurement values from n?1 voltage sensors are averaged, (b) the deviation of a voltage measurement value of the remaining voltage sensor from the averaged voltage measurement value is determined, and (c) if the deviation satisfies a specified criterion, an error message relating to a fault of the remaining voltage sensor is output and at least steps (a) to (b) are carried out for the voltage sensors in a commutated manner.

Abstract: Embodiments of the present disclosure include a device for repositioning papillary muscles, including a band configured to at least partially surround a cluster of papillary muscles. The cluster of papillary muscles may have an outer peripheral boundary, and the band may include a first end and a second end. The device for repositioning papillary muscles may further include a winch coupled to a location proximate the first end of the band. The winch may be configured to adjust a length of the band to apposition the papillary muscles in the cluster.

Abstract: A device for inductively transferring electrical energy and/or data from a primary-sided carrier to at least one secondary-sided recipient which can be positioned on the carrier has a meander-shaped winding on the primary side and at least one meander-shaped winding on the secondary side.

Abstract: The present invention provides immunogenic compositions, nucleic acid molecules and VLPs suitable as Norovirus vaccine candidates. Further provided are host cells for producing the biological material as well as methods for producing and/or purifying the immunogenic compositions and VLPs. Further provided is an immunogenic composition for use in methods of preventing/treating a Norovirus infection in a subject.

Abstract: The invention relates to an arrangement for an electrically excited machine (100), comprising: a machine rotor (10); and an exciter device (30) for the electrical excitation of the machine (100), wherein the exciter device (30) comprises at least one energy transfer system (20) integrated in the machine rotor (10). Moreover, the invention relates to an electrically excited machine (100) comprising a machine stator (40) and an arrangement according to the invention.

Abstract: The present invention relates to a circuit arrangement having an active rectifier circuit, in particular on a secondary side of an inductive energy transmission path. The circuit arrangement has a half or full bridge of power transistors for rectifying an AC voltage induced in an input inductor of the circuit arrangement. The power transistors are connected to the input inductor in such a way that an auxiliary voltage is split off from the induced AC voltage for switching the power transistors. As a result, even large currents, which result in a low output voltage, can be transmitted without endangering the operation of the rectifier circuit.

Abstract: The present invention relates to a method for increasing the efficiency of an energy transfer device (100) with which electrical energy is converted contactlessly into electrical energy with the aid of a magnetic field in order to electrically excite a rotor of an electrical machine, comprising the step of: arranging an additional electrically conductive material layer (13) on at least one active part (12, 19, 35, 45) of the energy transfer device (100), wherein an active part of the energy transfer device (100) is a part of the energy transfer device (100) which is at least partially exposed to the magnetic field used for energy transfer, and wherein the electrical conductivity of the additional material layer (13) is greater than the electrical conductivity of the at least one active part (12, 19, 35, 45). Moreover, the invention relates to an energy transfer device (100) and to a use of an electrically conductive material.

Abstract: A circuit for inductively transferring electrical energy from a primary side to a secondary side has a primary-sided autoresonant power oscillator compensated in parallel having a primary inductivity and serially compensated secondary sides each having a secondary inductivity.

Abstract: A ventilation system for a vehicle interior has an air guide for guiding air into the vehicle interior, an ionization device for ionizing the air in the air guide, an air outlet for transferring the air from the air guide into the vehicle interior, and a deflecting device in the air outlet, designed to produce an electric and/or magnetic field, for deflecting the ionized air.

Abstract: Provided is a method for producing and/or purifying measles virus (MV) particles from a sample, the method comprising in sequential order the following steps loading a sample containing MV particles and one or more impurities onto a stationary phase material for carrying out flow-through chromatography to bind at least a fraction of the impurities contained in the sample and to produce a flow-through comprising at least a fraction of the MV particles contained in the sample; carrying out filtration, preferably ultrafiltration, and obtaining a retentate having an increased MV titer relative to the MV titer comprised in the flow-through. Further provided is a system for producing and/or purifying MV particles, comprising at least one bioreactor; a clarification unit, preferably a dead end filter unit, downstream to the bioreactor; a flow through chromatography unit downstream to the clarification unit; and a filtration unit, downstream to the flow through chromatography unit.

Abstract: A device for inductively transferring electrical energy and/or data from a primary-sided carrier to at least one positionable secondary-sided recipient includes at least one primary-sided coil arrangement, which inductively interacts with at least one secondary-sided coil arrangement. Meander-shaped windings of a predeterminable winding number of the primary-sided and/or secondary-sided coil arrangement are arranged on at least one flexible carrier by embroidering a high frequency strand, and the meander-shaped windings have straight courses in the region of crossovers of the embroidered high frequency strands.

Abstract: The invention relates to a cardiac lead extraction device, comprising: a handle; an elongated body having a first proximal end, a first distal end, and a first lumen extending from said first proximal end toward said first distal end, said lumen sized and shaped to fit over a cardiac lead; a controllable bendable flexible portion more flexible that said elongated body and having a second proximal end, a second distal end and a second lumen extending from said second proximal end toward said second distal end, said lumen sized and shaped to fit over a cardiac lead; said second proximal end interconnected to said first distal end; said second distal end interconnected to an operational distal end; wherein said operational distal end comprises at least one lead extraction assistive tool, said lead extraction helping tool is activated by a motor located at said handle or proximally to said handle.

Abstract: Architecture introduces a new pattern operator referred to as called an augmented transition network (ATN), which is a streaming adaptation of non-reentrant, fixed-state ATNs for dynamic patterns. Additional user-defined information is associated with automaton states and is accessible to transitions during execution. ATNs are created that directly model complex pattern continuous queries with arbitrary cycles in a transition graph. The architecture can express the desire to ignore some events during pattern detection, and can also detect the absence of data as part of a pattern. The architecture facilitates efficient support for negation, ignorable events, and state cleanup based on predicate punctuations.

Abstract: A circuit for inductively transferring electrical energy from a primary side to a secondary side has a primary-sided autoresonant power oscillator compensated in parallel having a primary inductivity and serially compensated secondary sides each having a secondary inductivity.

Abstract: A device for inductively transferring electrical energy and/or data from a primary-sided carrier to at least one secondary-sided recipient which can be positioned on the carrier has a meander-shaped winding on the primary side and at least one meander-shaped winding on the secondary side.

Abstract: A device for inductively transferring electrical energy and/or data from a primary-sided carrier to at least one positionable secondary-sided recipient includes at least one primary-sided coil arrangement, which inductively interacts with at least one secondary-sided coil arrangement. Meander-shaped windings of a predeterminable winding number of the primary-sided and/or secondary-sided coil arrangement are arranged on at least one flexible carrier by embroidering a high frequency strand, and the meander-shaped windings have straight courses in the region of crossovers of the embroidered high frequency strands.

Abstract: Architecture introduces a new pattern operator referred to as called an augmented transition network (ATN), which is a streaming adaptation of non-reentrant, fixed-state ATNs for dynamic patterns. Additional user-defined information is associated with automaton states and is accessible to transitions during execution. ATNs are created that directly model complex pattern continuous queries with arbitrary cycles in a transition graph. The architecture can express the desire to ignore some events during pattern detection, and can also detect the absence of data as part of a pattern. The architecture facilitates efficient support for negation, ignorable events, and state cleanup based on predicate punctuations.