Abstract: The invention relates to acid addition salts of piperazine derivatives, as well as solid forms, such as polymorphic forms, thereof, which are useful as pharmaceutical ingredients and, in particular, as glycosidase inhibitors.

Abstract: A composition comprising a first infrared absorbing material which is a doped metal oxide comprising indium and/or tin; and a second infrared absorbing material which is a compound selected from: or a salt or polymer thereof, wherein —M is a metal selected from a group 3-10 (Group 1MB-VIII) element or a lanthanide; —R1 is selected from hydrogen, phosphonate, sulphonate, nitro, halo, cyano, thiocyano, thioalkyl, thioaryl, alkyl, alkoxy, aryl, aryloxy, amines, substituted amines and substituted aryl; —one of R2 and R3 is oxygen and the other of R2 and R3 is NO; —n is a number corresponding to half the co-ordination number of the metal M; —each L and L? is independently a ligand complexed to the metal M; and —y is a number corresponding to the co-ordination number of the metal M.

Abstract: A method of colouring an eyebrow, the method comprising: (i) contacting the eyebrow with a colouring composition comprising: (a) a dye compound; (b) an organic acid; and (c) an aromatic compound.

Abstract: The present invention relates to new solid forms of a plasma kallikrein inhibitor, a pharmaceutical composition containing them and their use in therapy. Also provided are processes for preparing the solid forms of the present invention.

Abstract: The invention provides new polymorphs of N-[(2,6-difluoro-3-methoxyphenyl)methyl]-3-(methoxymethyl)-1-({4-[(2-oxopyridin-1-yl)methyl]phenyl}methyl)pyrazole-4-carboxamide, pharmaceutical compositions containing them and their use in therapy.

Abstract: The invention provides new polymorphs of N-[(3-fluoro-4-methoxypyridin-2-yl)methyl]-3-(methoxymethyl)-1-({4-[(2-oxopyridin-1-yl)methyl]phenyl}methyl)pyrazole-4-carboxamide and salts thereof, pharmaceutical compositions containing them and their use as kallikrein inhibitors in therapy

Abstract: The invention provides new polymorphs of N-[(6-cyano-2-fluoro-3-methoxyphenyl)methyl]-3-(methoxymethyl)-1-({4-[(2-oxopyridin-1-yl)methyl]phenyl}methyl)pyrazole-4-carboxamide, pharmaceutical compositions containing them and their use in therapy.

Abstract: Various implementations described herein relate to systems and methods for correcting data from memory systems such as a plurality of non-volatile memory devices of a Solid State Drive (SSD), including but not limited to, receiving frames of the data from the plurality of non-volatile memory devices, allocating the frames among pooled frontline Error Correction Code (ECC) decoders, decoding, by the pooled frontline ECC decoders, the frames to output first decoded frames, and returning the first decoded frames to the read channels.

Abstract: In some examples, region cloning may include obtaining a clone request to clone a logical range of a source backup. The clone request may specify the source backup, a logical start offset, and a logical end offset. A source manifest associated with the logical range of the source backup may be determined. A start entry of the source manifest may be identified based on the logical start offset. The start entry may represent a start data chunk. A determination may be made as to whether the logical start offset represents an intermediate position of the start data chunk, and if so, a start partial chunk entry representing a sub-range of the start data chunk may be appended to a destination manifest. A backup of the logical range of the source backup may be generated based on the destination manifest with the appended start partial chunk entry.

Abstract: In some examples, region cloning may include obtaining a clone request to clone a logical range of a source backup. The clone request may specify the source backup, a logical start offset, and a logical end offset. A source manifest associated with the logical range of the source backup may be determined. A start entry of the source manifest may be identified based on the logical start offset. The start entry may represent a start data chunk. A determination may be made as to whether the logical start offset represents an intermediate position of the start data chunk, and if so, a start partial chunk entry representing a sub-range of the start data chunk may be appended to a destination manifest. A backup of the logical range of the source backup may be generated based on the destination manifest with the appended start partial chunk entry.

Abstract: The invention relates to acid addition salts of piperazine derivatives, as well as solid forms, such as polymorphic forms, thereof, which are useful as pharmaceutical ingredients and, in particular, as glycosidase inhibitors.

Abstract: Various implementations are directed to systems and methods for maintaining integrity and reliability of data in an SSD device using error correction coding. According to certain aspects, for frames of data having an ECC code with two or more sub-codes, while one sub-decoder is not in use it could be used to start a decode of another frame. By “interleaving” and alternating the frames between sub-decoders, two or more frames can be decoded simultaneously in an efficient manner. This can clearly be extended to more sub-codes (i.e. dimensions greater than two).

Abstract: The present invention relates generally to combinations comprising an alkaline compound and an ammonium compound that are useful for reducing the number of free living parasitic helminths on various surfaces, to methods of using such combinations, and to the use of such combinations for killing helminths, particularly nematodes.

Abstract: A method for fast calculation of a frame error rate (FER) of an error correcting code (ECC) soft decoder using a soft read process includes determining an MI-FER conversion data structure based on a relationship between mutual information (MI) of input channels and output channels of a memory, and FER of the ECC soft decoder, and decoding an encoded data codeword stored in a memory page of the memory and read using a soft read process. The method further includes generating a set of joint probability values using the information from the soft read process and data indicating true bit values for the data codeword, determining an MI value using the set of joint probability values, and determining an FER estimate using the MI-FER conversion data structure.

Abstract: Various implementations described herein relate to systems and methods for correcting data from memory systems such as a plurality of non-volatile memory devices of a Solid State Drive (SSD), including but not limited to, receiving frames of the data from the plurality of non-volatile memory devices, allocating the frames among pooled frontline Error Correction Code (ECC) decoders, decoding, by the pooled frontline ECC decoders, the frames to output first decoded frames, and returning the first decoded frames to the read channels.

Abstract: The present invention relates to novel hair treatment materials, and in particular materials for shaping hair and/or strengthening the hair. Also described are the use of these compounds in hair care formulations for shaping, straightening, strengthening or treating the hair, and the use of the compounds for hair straightening and/or hair strengthening.

Abstract: The present invention provides a coloured fibre comprising one or more composite filaments of cellulose and cellulose acetate, wherein the colour is effected by a disperse dye.

Abstract: The present invention provides the use of fibres comprising one or more composite filaments of cellulose and cellulose acetate, as a bleach activator.

Abstract: The present invention is directed roof edge seal and barrier devices and their method of manufacture. A method of manufacturing a comb-like sealing strip for use as a roof edge seal or barrier comprises stamping or cutting an elongate strip of material along a sinuous path located between the edges of the strip and then separating the strip into two portions, each of which consists of a fixing edge corresponding to the edge of the original strip from which project a series of teeth or prongs forming a comb structure.

Abstract: The present invention relates generally to combinations comprising an alkaline compound and an ammonium compound that are useful for reducing the number of free living parasitic helminths on various surfaces, to methods of using such combinations, and to the use of such combinations for killing helminths, particularly nematodes.