Abstract: According to some embodiments, a sensor device for determining forces exerted by a cyclist on a pedal of a bicycle is provided. The sensor device includes a plurality of sensors coupled to a substrate, and wiring coupled to the sensors and the substrate, wherein the sensors, the substrate, and the wiring are housed inside a pedal spindle coupled to the pedal. The sensor device may also be used in a system for improving a pedaling technique of a cyclist.

Abstract: An apparatus for forming an end effector includes a welding device having a welder positioned adjacent to a base, and a die coupled to one end of the welder. The base and the welder are movable relative to each other. The welder, base or die includes a source of heat that is applied to a portion of the suture disposed between the welder and the base.

Abstract: A suture including a knotted end effector is provided. The suture includes a body portion defining a longitudinal axis and an end effector integrally formed from the body portion, the end effector having first and second sections, each section including at least two throws, the at least two throws of the second section passing through the at least two throws of the first section. The number of throws in the first section may be the same or different from the number of throws in the second section.

Abstract: The present invention is directed to novel substituted pyrroline compounds useful as kinase inhibitors and methods for treating or ameliorating a kinase mediated disorder.

Abstract: The present invention is directed to novel substituted pyrroline compounds useful as kinase inhibitors and methods for treating or ameliorating a kinase mediated disorder.

Abstract: The present invention is directed to novel substituted pyrroline compounds useful as kinase inhibitors and methods for treating or ameliorating a kinase mediated disorder.

Abstract: According to some embodiments, a sensor device for determining forces exerted by a cyclist on a pedal of a bicycle is provided. The sensor device includes a plurality of sensors coupled to a substrate, and wiring coupled to the sensors and the substrate, wherein the sensors, the substrate, and the wiring are housed inside a pedal spindle coupled to the pedal. The sensor device may also be used in a system for improving a pedaling technique of a cyclist.

Abstract: The present invention is directed to novel substituted pyrroline compounds useful as kinase inhibitors and methods for treating or ameliorating a kinase mediated disorder.

Abstract: The present invention is directed to novel substituted pyrroline compounds useful as kinase inhibitors and methods for treating or ameliorating a kinase mediated disorder.

Abstract: Apparatus and methods are configured to coat a medical device, such as a stent, with a beneficial medicinal agent using one or more liquid feeds and one or more micromist nozzles. In one implementation, an agent coating rig includes a vertical adjustment means, a rotation means, and a traverse adjustment means for moving a medical device along virtually any point on an x or y axis. In additional or alternative implementations, the agent coating rig can further include a secondary horizontal adjustment means that allows adjustment along virtually any point on a z axis. Furthermore, methods and apparatus are provided for distributing the beneficial agent on the medical device, including delivering the beneficial agent efficiently over time.

Abstract: The present invention is directed to novel substituted pyrroline compounds useful as kinase inhibitors and methods for treating or ameliorating a kinase mediated disorder.

Abstract: Disclosed are stent holding devices having a support mandrel and one or more stent retaining fixtures disposed on the mandrel. The retaining fixture may include a character identifier to facilitate tracking a stent mounted on the holding device. The retaining fixture may include a conical protrusion and a conical recess to allow any number of retaining fixtures to engage each other and be stacked on the mandrel. The retaining fixture may include a tubular member having a spiral cut that enables the diameter of the tubular member to be adjusted to allow for a frictional fit on the mandrel. The retaining fixture may have a Z-shaped or T-shaped structure configured to retain a stent. The stent retaining fixture may also have a filament for retaining a stent.

Abstract: An oxygen-reducing catalyst layer, and a method of making the oxygen-reducing catalyst layer, where the oxygen-reducing catalyst layer includes a catalytic material film disposed on a substrate with the use of physical vapor deposition and thermal treatment. The catalytic material film includes a transition metal that is substantially free of platinum. At least one of the physical vapor deposition and the thermal treatment is performed in a processing environment comprising a nitrogen-containing gas.

Abstract: An oxygen-reducing catalyst layer, and a method of making the oxygen-reducing catalyst layer, where the oxygen-reducing catalyst layer includes a catalytic material film disposed on a substrate with the use of physical vapor deposition and thermal treatment. The catalytic material film includes a transition metal that is substantially free of platinum. At least one of the physical vapor deposition and the thermal treatment is performed in a processing environment comprising a nitrogen-containing gas.

Abstract: A messaging device may include a memory configured to store a first message from a first caller and intended for a called party and to store information identifying a group that includes a number of broadcast parties that include the first caller. The messaging device may include a processor configured to receive a reply message from the called party and to broadcast the reply message to at least a subset of the group.

Abstract: A method includes electronically identifying a first item that a customer intends to purchase while the customer is shopping and electronically providing content to the customer in response to the identifying to entice the customer to purchase a second, different item.

Abstract: A method and system for authenticating requests for accessing network resources are described. Network address information may be associated with a network resource user. An authenticator may maintain the associated network address information. The authenticator may receive, from a requesting party, a request to authenticate the network resource user, where the request may include a network address identifier. The network resource user may be authenticated based on the network address information and the network address identifier. The authentication determination may be forwarded to the requesting party for purposes of controlling access to a network resource of a network resource provider in response to an access request made by the network resource user.

Abstract: The present invention is directed to novel substituted pyrroline compounds useful as kinase inhibitors and methods for treating or ameliorating a kinase mediated disorder.

Abstract: The present invention is directed to novel substituted pyrroline compounds useful as kinase inhibitors and methods for treating or ameliorating a kinase mediated disorder.