Patents by Inventor David P. Cistola

David P. Cistola has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND TOOLS FOR DIAGNOSING INSULIN RESISTANCE AND ASSESSING HEALTH STATUS USING NMR RELAXATION TIMES FOR WATER
    Publication number: 20220039680
    Abstract: The subject invention pertains to a method that involves at least three steps: (1) acquisition of a NMR data set or spin relaxation curve for plasma, serum or whole blood samples, (2) analysis of the NMR data or relaxation curve to extract the T2 relaxation times for water (or surrogates thereof), and (3) conversion of the water T2 (or surrogates thereof) into a measure of someone's health status (referred to as a T2 health score depending on the T2 value associated with the score). The T2 health score utilizes a statistical database derived from previous studies of subjects of normal, healthy individuals to those having varying degrees of hidden or subclinical metabolic abnormalities, such as inflammation, insulin resistance, lipid abnormalities (dyslipidemia), oxidative stress or other abnormalities, and provides a measure of a subject's overall health status.
    Type: Application
    Filed: October 25, 2021
    Publication date: February 10, 2022
    Inventors: DAVID P. CISTOLA, MICHELLE D. ROBINSON
  • Method and system for non-invasive measurement of metabolic health
    Patent number: 10775458
    Abstract: A medical testing system comprises a housing, at least one magnet assembly configured around a probe configured to accept a human finger, formed in the housing wherein the at least one magnet assembly creates a permanent magnetic field around the probe, an RF signal generator configured to create a temporary magnetic field perpendicular to the permanent magnetic field in the housing, and an NMR coil assembly wherein a change in the permanent magnetic field induces a voltage in the NMR coil assembly.
    Type: Grant
    Filed: March 5, 2018
    Date of Patent: September 15, 2020
    Assignee: Texas Tech University System
    Inventors: David P. Cistola, Vipulkumar Patel
  • Methods for monitoring changes in the core of lipoprotein particles in metabolism and disease
    Patent number: 10613169
    Abstract: A method is disclosed for measuring the properties of protein and lipoprotein elements in a sample.
    Type: Grant
    Filed: January 20, 2017
    Date of Patent: April 7, 2020
    Assignee: East Carolina University
    Inventors: David P. Cistola, Michelle Robinson
  • METHOD AND SYSTEM FOR NON-INVASIVE MEASUREMENT OF METABOLIC HEALTH
    Publication number: 20190271749
    Abstract: A medical testing system comprises a housing, at least one magnet assembly configured around a probe configured to accept a human finger, formed in the housing wherein the at least one magnet assembly creates a permanent magnetic field around the probe, an RF signal generator configured to create a temporary magnetic field perpendicular to the permanent magnetic field in the housing, and an NMR coil assembly wherein a change in the permanent magnetic field induces a voltage in the NMR coil assembly.
    Type: Application
    Filed: March 5, 2018
    Publication date: September 5, 2019
    Inventors: David P. Cistola, Vipulkumar Patel
  • METHODS AND TOOLS FOR DIAGNOSING INSULIN RESISTANCE AND ASSESSING HEALTH STATUS USING NMR RELAXATION TIMES FOR WATER
    Publication number: 20180020947
    Abstract: The subject invention pertains to a method that involves at least three steps: (1) acquisition of a NMR data set or spin relaxation curve for plasma, serum or whole blood samples, or for tissues monitored from outside the body, (2) analysis of the NMR data or relaxation curve to extract the T2 and/or T1 relaxation times for water (or surrogates thereof), and (3) conversion of the water T2 and/or T1 values (or surrogates thereof) into a measure of someone's health status (referred to as a T2 or T1 health score depending on the value (T1 or T2 or both T1 and T2) associated with the score).
    Type: Application
    Filed: February 6, 2016
    Publication date: January 25, 2018
    Inventors: DAVID P. CISTOLA, MICHELLE D. ROBINSON
  • Methods for Monitoring Changes in the Core of Lipoprotein Particles in Metabolism and Disease
    Publication number: 20170192069
    Abstract: A method is disclosed for measuring the properties of protein and lipoprotein elements in a sample.
    Type: Application
    Filed: January 20, 2017
    Publication date: July 6, 2017
    Applicant: East Carolina University
    Inventors: David P. Cistola, Michelle Robinson
  • NMR method for monitoring changes in the core of lipoprotein particles in metabolism and disease
    Patent number: 9551768
    Abstract: A method is disclosed for measuring the properties of protein and lipoprotein elements in a sample.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: January 24, 2017
    Assignee: East Carolina University
    Inventors: David P. Cistola, Michelle Robinson
  • METHODS FOR MONITORING CHANGES IN THE CORE OF LIPOPROTEIN PARTICLES IN METABOLISM AND DISEASE
    Publication number: 20140273247
    Abstract: A method is disclosed for measuring the properties of protein and lipoprotein elements in a sample.
    Type: Application
    Filed: March 15, 2013
    Publication date: September 18, 2014
    Applicant: EAST CAROLINA UNIVERSITY
    Inventors: David P. Cistola, Michelle Robinson