Patents by Inventor David P. Kosow

David P. Kosow has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Factor VIII complex purification using heparin affinity chromatography
    Patent number: 5110907
    Abstract: There is provided in accordance with the practice of this invention, a process for separating Factor VIII complex from an impure protein fraction containing Factor VIII complex. An aqueous solution of the impure protein fraction containing Factor VIII complex is applied to a heparin coupled chromatographic medium to bind the Factor VIII complex to the medium. The Factor VIII is then recovered from the heparin coupled chromatographic medium by elution with an aqueous CaCl.sub.2 solution.
    Type: Grant
    Filed: August 1, 1989
    Date of Patent: May 5, 1992
    Assignee: Alpha Therapeutic Corporation
    Inventors: David P. Kosow, Prabir Bhattacharya, Charles F. Sternburg
  • Plasma protein concentrates of reduced thrombogenicity and their use in clinical replacement therapy
    Patent number: 4447416
    Abstract: Plasma concentrates of vitamin-K dependent clotting factors of reduced thrombogenic potential useful for clinical replacement therapy in deficiency diseases of these clotting factors are provided. Preferably, concentrates substantially devoid of zymogens extraneous to the deficient factor are employed.
    Type: Grant
    Filed: April 28, 1982
    Date of Patent: May 8, 1984
    Assignee: American National Red Cross
    Inventors: Doris Menache-Aronson, David P. Kosow, Carolyn L. Orthner, H. Evan Behre
  • Heparin enhanced process for separating antihemophilic factor (Factor VIII) and fibronectin from cryoprecipitate
    Patent number: H1509
    Abstract: A process is provided for preparing fibronectin and antihemophilic factor (Factor VIII) concentrates from a blood plasma cryoprecipitate.
    Type: Grant
    Filed: June 4, 1993
    Date of Patent: December 5, 1995
    Inventors: Harutyun Eran, Duk S. Hwang, David P. Kosow