Abstract: Methods and compositions for reducing fibrosis and cirrhosis are provided in which an effective dose of an admixture of a polysaccharide compound and, for example, a compound selected from the group consisting of antibodies specific to intracellular or cell-surface: (i) beta-PDGF receptors; (ii) synaptophysin; (iii) zvegf3; (iv) CCR1 receptors; (v) connective tissue growth factor; (vi) alpha 1-smooth muscle actin; (vii) matrix metalloproteinases MMP 2 and MMP9; (viii) matrix metalloproteinase inhibitors TIMP1 and TMP2; (ix) integrins; (x) TFG-?1; (xi) endothelin receptor antagonists; and (xii) collagen synthesis and degradation modulating compounds; (xiii) actin synthesis and degradation modulating compounds; and (xiv) tyrosine kinases is administered to an animal in order to treat fibrosis.

Abstract: A composition of chemically purified soluble mannans from legumes' seeds (e.g. Ceratonia siliqua, Caesalpinia spinosa Trigonelle foenum-graecum, and Cyamopsis tetragonolobus) and their use in the assembly of palatable dietary supplements is disclosed herein. The fractionation process provides high-quality physiologically soluble, chemically modified and purified homogeneous size polysaccharide fibers, devoid of natural impurities, for example proteins, alkaloids, glycoalkaloids, and/or environmental impurities including heavy metals, agricultural residues and microbial toxins. This process provides hypoallergenic dietary fibers devoid of any potential allergens, cytotoxins, and gastrointestinal toxins.

Abstract: Methods and compositions for reducing fibrosis and cirrhosis are provided in which an effective dose of an admixture of a polysaccharide compound and, for example, a compound selected from the group consisting of antibodies specific to intracellular or cell-surface: (i) beta-PDGF receptors; (ii) synaptophysin; (iii) zvegf3; (iv) CCR1 receptors; (v) connective tissue growth factor; (vi) alpha 1-smooth muscle actin; (vii) matrix metalloproteinases MMP 2 and MMP9; (viii) matrix metalloproteinase inhibitors TIMP1 and TMP2; (ix) integrins; (x) TFG-?1; (xi) endothelin receptor antagonists; and (xii) collagen synthesis and degradation modulating compounds; (xiii) actin synthesis and degradation modulating compounds; and (xiv) tyrosine kinases is administered to an animal in order to treat fibrosis.

Abstract: Methods and compositions for reducing fibrosis and cirrhosis are provided in which an effective dose of an admixture of a polysaccharide compound and, for example, a compound selected from the group consisting of antibodies specific to intracellular or cell-surface: (i) beta-PDGF receptors; (ii) synaptophysin; (iii) zvegf3; (iv) CCR1 receptors; (v) connective tissue growth factor; (vi) alpha 1-smooth muscle actin; (vii) matrix metalloproteinases MMP 2 and MMP9; (viii) matrix metalloproteinase inhibitors TIMP1 and TMP2; (ix) integrins; (x) TFG-?1; (xi) endothelin receptor antagonists; and (xii) collagen synthesis and degradation modulating compounds; (xiii) actin synthesis and degradation modulating compounds; and (xiv) tyrosine kinases is administered to an animal in order to treat fibrosis.

Abstract: Methods and compositions for reducing fibrosis are provided, wherein an admixture of at least a galactose-pronged polymer and a pharmaceutically acceptable carrier is obtained and administered, wherein the administration of a sufficient amount of the admixture is measured by a quantitative change in a fibrosis tissue marker.

Abstract: Methods and compositions for reducing fibrosis and cirrhosis are provided in which an effective dose of an admixture of a polysaccharide compound and, for example, a compound selected from the group consisting of antibodies specific to intracellular or cell-surface: (i) beta-PDGF receptors; (ii) synaptophysin; (iii) zvegf3; (iv) CCR1 receptors; (v) connective tissue growth factor; (vi) alpha 1-smooth muscle actin; (vii) matrix metalloproteinases MMP 2 and MMP9; (viii) matrix metalloproteinase inhibitors TIMP1 and TMP2; (ix) integrins; (x) TFG-?1; (xi) endothelin receptor antagonists; and (xii) collagen synthesis and degradation modulating compounds; (xiii) actin synthesis and degradation modulating compounds; and (xiv) tyrosine kinases is administered to an animal in order to treat fibrosis.

Abstract: An archer's hand support structure apparatus and method of use is disclosed to help stabilize an archer's hand during string draw and string release of an archer's bow. The archer's hand support structure apparatus includes an archer's bow that has a handle portion and a rigid member that is affixed to the handle portion, the rigid member is constructed of substantially non-pliant material adapted to encase the archer's hand, the rigid member having a finger aperture portion extending adjacent to an archer's distal hand portion and a wrist aperture portion extending adjacent to an archer's proximal hand portion. The rigid member also includes an expansion slot therethrough disposed substantially adjacent to the wrist aperture portion to temporarily expand the wrist aperture portion for operationally accommodating an archer's fingers communication from the wrist aperture to the finger aperture.

Abstract: This subject invention features a robot deployed weapon system. A remotely controlled mobile robot has a weapon mounted to the robot. There is a firing circuit for the weapon and a weapon interrupt module on board the robot. An operator control unit is for remotely operating the robot and the weapon. The operating control unit preferably includes a stop switch. Also, a separate operator module is in communication with the weapon interrupt module. Preferably, the operator module includes a kill switch. There are two communication links. The first communication link is between the operator control unit and the robot. This communication link is configured to safe the weapon if the stop switch is activated and/or the first communication link degrades. The second communication link is between the operator module and the weapon interrupt module. The communication link is configured to safe the weapon if the kill switch is activated and/or the second communication link degrades.

Abstract: Disclosed herein are compositions and methods for treating diseases such as cancer. The compositions comprise one or more polysaccharides in an admixture with one or more therapeutic agents. This admixture can be administered to a subject in need thereof using any known method of administration. The therapeutic agent, if administered alone, can cause undesirable side-effects in the subject. The polysaccharide component minimizes or eliminates these side effects. The compositions described herein effectuate an enhanced therapeutic effect along with reduced toxicity.

Abstract: Disclosed herein are compositions and methods for treating diseases such as cancer. The compositions comprise one or more polysaccharides in an admixture with one or more therapeutic agents. This admixture can be administered to a subject in need thereof using any known method of administration. The therapeutic agent, if administered alone, can cause undesirable side-effects in the subject. The polysaccharide component minimizes or eliminates these side effects. The compositions described herein effectuate an enhanced therapeutic effect along with reduced toxicity.

Abstract: This subject invention features a robot deployed weapon system. A remotely controlled mobile robot has a weapon mounted to the robot. There is a firing circuit for the weapon and a weapon interrupt module on board the robot. An operator control unit is for remotely operating the robot and the weapon. The operating control unit preferably includes a stop switch. Also, a separate operator module is in communication with the weapon interrupt module. Preferably, the operator module includes a kill switch. There are two communication links. The first communication link is between the operator control unit and the robot. This communication link is configured to safe the weapon if the stop switch is activated and/or the first communication link degrades. The second communication link is between the operator module and the weapon interrupt module. The communication link is configured to safe the weapon if the kill switch is activated and/or the second communication link degrades.

Abstract: An improved wine preservation and delivery system and method providing a container stopper, a replacement fluid and/or air pipe disposed through the container stopper, a flexible bladder for displacing wine as it is filled with fluid and/or air, and a fluid outlet pipe.

Abstract: A modified pectin consists essentially of neutral sugar sequences with a low degree of branching capable of preventing tumor cell migration and cell to cell and cell to substratum adhesion.

Abstract: Described herein is a microbial composition used to enhance anti-cancer drugs. Specifically, microbial compositions that comprise a part of or an entire microorganism having surface lectins specific to carbohydrate moieties on tumor surface combined with an oncolytic agent.

Abstract: Disclosed herein are compositions and methods for treating diseases such as cancer. The compositions comprise one or more polysaccharides in an admixture with one or more therapeutic agents. This admixture can be administered to a subject in need thereof using any known method of administration. The therapeutic agent, if administered alone, can cause undesirable side-effects in the subject. The polysaccharide component minimizes or eliminates these side effects. The compositions described herein effectuate an enhanced therapeutic effect along with reduced toxicity.

Abstract: Methods and compositions for reducing fibrosis and cirrhosis are provided in which an effective dose of an admixture of a polysaccharide compound and, for example, a compound selected from the group consisting of antibodies specific to intracellular or cell-surface: (i) beta-PDGF receptors; (ii) synaptophysin; (iii) zvegf3; (iv) CCR1 receptors; (v) connective tissue growth factor; (vi) alpha 1-smooth muscle actin; (vii) matrix metalloproteinases MMP 2 and MMP9; (viii) matrix metalloproteinase inhibitors TIMP1 and TMP2; (ix) integrins; (x) TFG-?1; (xi) endothelin receptor antagonists; and (xii) collagen synthesis and degradation modulating compounds; (xiii) actin synthesis and degradation modulating compounds; and (xiv) tyrosine kinases is administered to an animal in order to treat fibrosis.

Abstract: Disclosed herein are compositions comprising a drug linked to a multivalent ligand polysaccharide and the use of this composition in the prevention and treatment of cancer. In one aspect, the polysaccharide is obtained by physical and chemical treatment of naturally occurring polymers or semi synthetic polymers which are bridged specifically with one or more anti-cancer chemotherapeutic agents. Another aspect is directed to the effective delivery of the polysaccharide together with the chemotherapeutic agent to diseased tissue including cancerous tissue.

Abstract: A solid ink stick melting apparatus is incorporated in a phase change printer to provide melted ink under pressure to a print head. The solid ink stick melting apparatus includes an ink stick melt chamber having an enclosure with at least one heated wall, an inlet for receiving an ink stick, and an outlet for melted ink flow from the enclosure, and a seal mounted proximate the inlet to engage an ink stick passing through the seal so that the seal and the ink stick form a barrier and retain melted ink within the enclosure.

Abstract: A cryptographically signed filesystem provides a central database resident on a server that contains database objects. The server creates startup software to be installed in a client system's read only memory. The startup software contains a hash value for a second stage loader. The server also creates software for a bootstrap loader object which typically contains the operating system for a client system and also the bootstrap loader's hash value and a digital signature that is unique to the server. The startup software and objects created by the server are initially installed on a client device at the time of manufacture. The server can update a client's bootstrap loader and root filesystem at any time through the transmission of slices.

Abstract: An authentication system for securing information within a disk drive to be read and written to only by a specific host computer such that it is difficult or impossible to access the drive by any system other than a designated host is disclosed. While the invention is similar in intent to a password scheme, it significantly more secure. The invention thus provides a secure environment for important information stored within a disk drive. The information can only be accessed by a host if the host can respond to random challenges asked by the disk drive. The host's responses are generated using a cryptography chip processing a specific algorithm. This technique allows the disk drive and the host to communicate using a coded security system where attempts to break the code and choose the correct password take longer to learn than the useful life of the disk drive itself.