Patents by Inventor David R. Corbin
David R. Corbin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230374529Abstract: Disclosed herein are methods and compositions for the repair of site specific nuclease binding sites by targeted integration and/or targeted excision of one or more sequences into a cell.Type: ApplicationFiled: March 7, 2023Publication date: November 23, 2023Applicant: CORTEVA AGRISCIENCE LLCInventors: DAVID R. CORBIN, WEI CHEN, STEPHEN NOVAK, RYAN M. LEE, SANDEEP KUMAR, ANDREW ASBERRY, ANDREW F. WORDEN
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Patent number: 11634721Abstract: Disclosed herein are methods and compositions for the repair of site specific nuclease binding sites by targeted integration and/or targeted excision of one or more sequences into a cell.Type: GrantFiled: December 6, 2017Date of Patent: April 25, 2023Inventors: David R. Corbin, Wei Chen, Stephen Novak, Ryan M. Lee, Sandeep Kumar, Andrew Asberry, Andrew F. Worden
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Patent number: 10415046Abstract: The present invention claims methods for the stable integration of exogenous DNA into a specific locus, E32, in the maize genome through the use of zinc finger nucleases. Maize plants and plant parts that were transformed by the methods of the invention are claimed. The invention is useful for creating desirable traits such as herbicide resistance, herbicide tolerance, insect resistance, insect tolerance, disease resistance, disease tolerance, stress tolerance, and stress resistance in maize The E32 locus represents a superior site for inserting foreign genes because native agronomic phenotypes are not disturbed.Type: GrantFiled: October 31, 2016Date of Patent: September 17, 2019Assignee: Dow AgroSciences LLCInventors: W. Michael Ainley, James W. Bing, David R. Corbin, Steven L. Evans, Joseph F. Petolino, Lakshmi Sastry-Dent, Steven A. Thompson, Steven R. Webb, Mary E. Welter, Ning Zhou
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Publication number: 20170044558Abstract: The present invention claims methods for the stable integration of exogenous DNA into a specific locus, E32, in the maize genome through the use of zinc finger nucleases. Maize plants and plant parts that were transformed by the methods of the invention are claimed. The invention is useful for creating desirable traits such as herbicide resistance, herbicide tolerance, insect resistance, insect tolerance, disease resistance, disease tolerance, stress tolerance, and stress resistance in maize The E32 locus represents a superior site for inserting foreign genes because native agronomic phenotypes are not disturbed.Type: ApplicationFiled: October 31, 2016Publication date: February 16, 2017Inventors: W. Michael AINLEY, James W. BING, David R. CORBIN, Steven L. EVANS, Joseph F. PETOLINO, Lakshmi SASTRY-DENT, Steven A. THOMPSON, Steven R. WEBB, Mary E. WELTER, Ning ZHOU
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Publication number: 20160270548Abstract: A sleeping system capable of customization so that at least six different levels of firmness may be achieved per bed. The system includes three layers which may be positioned by the end user in order to achieve the desired firmness. The present invention also includes a method of selling such interchangeable modular bedding. In the method, after selling the bedding, at least one of the three layers may be exchanged in order to achieve yet another alternate firmness level.Type: ApplicationFiled: March 22, 2016Publication date: September 22, 2016Inventors: DAVID R. CORBIN, STEPHEN S. RUSSO
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Patent number: 9289074Abstract: The present invention discloses a sleeping system capable of customization so that at least six different levels of firmness may be achieved per bed. The present invention discloses three layers which may be positioned by the end user in order to achieve the desired firmness. The present invention also includes a method of selling such interchangeable modular bedding. In the method, after selling the bedding, at least one of the three layers may be exchanged in order to achieve yet another alternate firmness level.Type: GrantFiled: April 20, 2011Date of Patent: March 22, 2016Inventors: David R. Corbin, Stephen S. Russo
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Patent number: 8440880Abstract: The present invention relates to a nucleic acid sequences from Xenorhabdus that encodes a GroEL protein. The invention encompasses nucleic acid molecules present in non-coding regions as well as nucleic acid molecules that encode proteins, fragments of proteins, tRNA's, fragments of tRNA's, rRNA's and fragments of rRNA's. In addition, protein and fragments of proteins so encoded and antibodies capable of binding the proteins are encompassed by the present invention. The invention also relates to methods of using the disclosed nucleic acid molecules, proteins, fragments of proteins, RNA'S, and antibodies, for example, for gene identification and analysis, and preparation of constructs.Type: GrantFiled: March 30, 2012Date of Patent: May 14, 2013Assignee: Monsanto Technology LLCInventors: David R. Corbin, Barry S. Goldman, Gregory J. Hinkle, Joseph E. Huesing, Thomas M. Malvar, Karina C. Krasomil-Osterfeld, Steven C. Slater, Sergei Spiridonov
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Patent number: 8344207Abstract: The present invention provides nucleotide sequences encoding an insecticidal protein exhibiting lepidopteran inhibitory activity, as well as a novel insecticidal protein referred to herein as a Cry1A.105 insecticide, transgenic plants expressing the insecticide, and methods for detecting the presence of the nucleotide sequences or the insecticide in a biological sample.Type: GrantFiled: May 23, 2011Date of Patent: January 1, 2013Assignee: Monsanto Technology LLCInventors: Natalia N. Bogdanova, David R. Corbin, Thomas M. Malvar, Frederick J. Perlak, James K. Roberts, Charles P. Romano
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Patent number: 8329986Abstract: Disclosed herein are methods and compositions for targeted integration of an exogenous sequence into a plant Zp15 locus, for example, for expression of a polypeptide of interest.Type: GrantFiled: December 17, 2009Date of Patent: December 11, 2012Assignees: Dow AgroSciences, LLC, Sangamo BioSciences, Inc.Inventors: Holly J. Butler, David R. Corbin, Yannick Doyon, Zhifang Gao, Vipula K. Shukla, Fyodor Urnov, Sarah E. Worden
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Publication number: 20120185974Abstract: The present invention relates to a nucleic acid sequence from Xenorhabdus that encodes a GroEL protein. The invention encompasses nucleic acid molecules present in non-coding regions as well as nucleic acid molecules that encode proteins, fragments of proteins, tRNA's, fragments of tRNA's, rRNA's and fragments of rRNA's. In addition, proteins and fragments of proteins so encoded and antibodies capable of binding the proteins are encompassed by the present invention. The invention also relates to methods of using the disclosed nucleic acid molecules, proteins, fragments of proteins, RNA's, and antibodies, for example, for gene identification and analysis, and preparation of constructs.Type: ApplicationFiled: March 30, 2012Publication date: July 19, 2012Applicant: MONSANTO TECHNOLOGY LLCInventors: David R. Corbin, Barry S. Goldman, Gregory J. Hinkle, Joseph E. Huesing, Thomas M. Malvar, Karina C. Krasomil-Osterfeld, Steven C. Slater, Sergei Spiridonov
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Publication number: 20110307978Abstract: The present invention provides nucleotide sequences encoding an insecticidal protein exhibiting lepidopteran inhibitory activity, as well as a novel insecticidal protein referred to herein as a Cry1A.105 insecticide, transgenic plants expressing the insecticide, and methods for detecting the presence of the nucleotide sequences or the insecticide in a biological sample.Type: ApplicationFiled: May 23, 2011Publication date: December 15, 2011Inventors: Natalia N. Bogdanova, David R. Corbin, Thomas M. Malvar, Frederick J. Perlak, James K. Roberts, Charles P. Romano
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Patent number: 8034997Abstract: The present invention provides nucleotide sequences encoding an insecticidal protein exhibiting lepidopteran inhibitory activity, as well as a novel insecticidal protein referred to herein as a Cry1A.105 insecticide, transgenic plants expressing the insecticide, and methods for detecting the presence of the nucleotide sequences or the insecticide in a biological sample.Type: GrantFiled: August 30, 2006Date of Patent: October 11, 2011Assignee: Monsanto Technology LLCInventors: Natalia N. Bogdanova, David R. Corbin, Thomas M. Malvar, Frederick J. Perlak, James K. Roberts, Charles P. Romano
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Patent number: 8030542Abstract: Disclosed is a means of controlling plant pests by a novel method of expressing Cry2A B. thuringiensis ?-endotoxins in plants. The invention comprises novel nucleic acid segments encoding proteins comprising Cry2A B. thuringiensis ?-endotoxins. The nucleic acid segments are disclosed, as are transformation vectors containing the nucleic acid segments, plants transformed with the claimed segments, methods for transforming plants, and methods of controlling plant infestation by pests.Type: GrantFiled: April 19, 2010Date of Patent: October 4, 2011Assignee: Monsanto Technology LLCInventors: David R. Corbin, Charles P. Romano
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Publication number: 20110166335Abstract: The present invention relates to nucleic acid sequences from Xenorhabdus and, in particular, to genomic DNA sequences, and to the insecticidal Xenorhabdus strain Xs85816. The invention encompasses nucleic acid molecules present in non-coding regions as well as nucleic acid molecules that encode proteins, fragments of proteins, tRNA's, fragments of tRNA's, rRNA's and fragments of rRNA's. In addition, proteins and fragments of proteins so encoded and antibodies capable of binding the proteins are encompassed by the present invention. The invention also relates to methods of using the disclosed nucleic acid molecules, proteins, fragments of proteins, RNA's, and antibodies, for example, for gene identification and analysis, and preparation of constructs.Type: ApplicationFiled: October 30, 2008Publication date: July 7, 2011Inventors: David R. Corbin, Barry S. Goldman, Gregory J. Hinkle, Joseph E. Huesing, Thomas M. Malvar, Karina C. Krasomil-Osterfeld, Steven C. Slater, Sergei Spirodonov
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Publication number: 20110167520Abstract: The present invention relates to nucleic acid sequences from Xenorhabdus and, in particular, to genomic DNA sequences, and to the insecticidal Xenorhabdus strain Xs85816. The invention encompasses nucleic acid molecules present in non-coding regions as well as nucleic acid molecules that encode proteins, fragments of proteins, tRNA's, fragments of tRNA's, rRNA's and fragments of rRNA's. In addition, proteins and fragments of proteins so encoded and antibodies capable of binding the proteins are encompassed by the present invention. The invention also relates to methods of using the disclosed nucleic acid molecules, proteins, fragments of proteins, RNA's, and antibodies, for example, for gene identification and analysis, and preparation of constructs.Type: ApplicationFiled: April 9, 2009Publication date: July 7, 2011Inventors: David R. Corbin, Barry S. Goldman, Gregory J. Hinkle, Joseph E. Huesing, Thomas M. Malvar, Karina C. Krasomil-Osterfeld, Steven C. Slater, Sergei Spiridonov
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Publication number: 20100319087Abstract: Disclosed is a means of controlling plant pests by a novel method of expressing Cry2A B. thuringiensis ?-endotoxins in plants. The invention comprises novel nucleic acid segments encoding proteins comprising Cry2A B. thuringiensis ?-endotoxins. The nucleic acid segments are disclosed, as are transformation vectors containing the nucleic acid segments, plants transformed with the claimed segments, methods for transforming plants, and methods of controlling plant infestation by pests.Type: ApplicationFiled: April 19, 2010Publication date: December 16, 2010Inventors: David R. Corbin, Charles P. Romano
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Publication number: 20100261614Abstract: The present invention relates to nucleic acid sequences from Bacillus thuringiensis and, in particular, to genomic DNA sequences. The invention encompasses nucleic acid molecules present in non-coding regions as well as nucleic acid molecules that encode proteins, fragments of proteins, tRNA's, fragments of tRNA's, rRNA's and fragments of rRNA's. In addition, proteins and fragments of proteins so encoded and antibodies capable of binding the proteins are encompassed by the present invention. The invention also relates to methods of using the disclosed nucleic acid molecules, proteins, fragments of proteins, RNA's, and antibodies, for example, for gene identification and analysis, and preparation of constructs.Type: ApplicationFiled: April 19, 2010Publication date: October 14, 2010Inventors: David R. Corbin, Thomas M. Malvar, Hridayabhiranjan Shukla
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Publication number: 20100199389Abstract: Disclosed herein are methods and compositions for targeted integration of an exogenous sequence into a plant Zp15 locus, for example, for expression of a polypeptide of interest.Type: ApplicationFiled: December 17, 2009Publication date: August 5, 2010Inventors: Holly J. Butler, David R. Corbin, Yannick Doyon, Zhifang Gao, Vipula K. Shukla, Fyodor Urnov, Sarah E. Worden
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Patent number: 7709666Abstract: Provided are recombinant constructs comprising DNA sequences encoding enzymes effective in altering the biosynthesis and accumulation of sterol compounds and tocopherols in transgenic plants. Also provided are methods of using such constructs to produce transgenic plants, seeds of which contain elevated levels of sitostanol and/or sitostanol esters, and ?-tocopherol, as well as reduced levels of campesterol and campestanol and their corresponding esters. These seeds also contain the novel sterol brassicastanol. Oil obtained from seeds of such transgenic plants is also provided. This oil can be used to prepare food and pharmaceutical compositions effective in lowering the level of low density lipoprotein cholesterol in blood serum. In addition, novel DNA sequences encoding plant steroid 5?-reductases are also disclosed.Type: GrantFiled: January 16, 2004Date of Patent: May 4, 2010Assignee: Monsanto Technology LLCInventors: Mylavarapu Venkatramesh, David R. Corbin, B. Ganesh Bhat, Sekhar S. Boddupalli, Robert J. Grebenok, Ganesh M. Kishore, Kathryn D. Lardizabal, Michael W. Lassner, Shaukat H. Rangwala, Balasulojini Karunanandaa
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Patent number: 7700838Abstract: The present invention relates to nucleic acid sequences from Bacillus thuringiensis and, in particular, to genomic DNA sequences. The invention encompasses nucleic acid molecules present in non-coding regions as well as nucleic acid molecules that encode proteins, fragments of proteins, tRNA's, fragments of tRNA's, rRNA's and fragments of rRNA's. In addition, proteins and fragments of proteins so encoded and antibodies capable of binding the proteins are encompassed by the present invention. The invention also relates to methods of using the disclosed nucleic acid molecules, proteins, fragments of proteins, RNA's, and antibodies, for example, for gene identification and analysis, and preparation of constructs.Type: GrantFiled: February 2, 2005Date of Patent: April 20, 2010Assignee: Monsanto Technology LLCInventors: David R. Corbin, Thomas M. Malvar, Hridayabhiranjan Shukla