Abstract: The present invention provides a method of reducing the major allergen in cat dander, Fel d1, and of reducing allergic response in mammals, including humans, sensitive to cat dander. Specifically to humans sensitive to the Fel d1 allergen that is shed by a cat. The treatment is achieved through administering to the cat itself a composition, which stimulates the cat's immune response to its own dander and Fel d1 polypeptide. The result is a reduction in the amount of Fel d1 shed by the cat, and a subsequent reduction or lowering of the level of allergic responsiveness in sensitized individuals.

Abstract: The present invention relates to novel bacterial isolates identified by their 16S rRNA DNA, that cause periodontal disease in companion animals, polynucleotide sequences contained therein, polypeptides encoded by such polynucleotide sequences and vaccines comprising such bacteria, polynucleotides, or polypeptides. Also provided are methods for treating and preventing periodontal disease and kits for detecting and treating periodontal disease kits for detecting and preventing periodontal disease.

Abstract: Methods to measure the duration of adequate immune memory for animal vaccines involving a retrospective analysis utilizing veterinary vaccine administration histories and clinical histories, and markers of immunity of animals in the field to derive a vaccine's duration of adequate immune memory.

Abstract: An attenuated infectious laryngotracheitis virus (ILT) that has the antigenic and virulence characteristics of ECACC at Accession No. V89042602, produces an average pock diameter on chorio-allantoic membrane of commercial eggs between 1.0 and 3. mm, exhibits substantially reduced virulence in comparison to ILT SA2 strain, and results in substantially less weight loss in poultry as compared to poultry infected with SA2. A method of producing this ILT virus by serially passaging ILT viral strain SA2 in primary cell cultures followed by serial passaging in embryonated eggs. A method for preventing infection by ILT virus in birds by administering a vaccine with an effective amount sufficient to elicit an immune response.