Abstract: Cushioning constructions for mattresses or chair cushions are given comfort features for severely immobilized patients. Otherwise, the problem is that, sit or lie still long enough and awful sores may develop. The cushioning constructions hereof are formed of plural or multiple layers of resilient materials of dissimilar softness/firmness and, moreover, these layers are partitioned into multiple zones across the layers of likewise dissimilar softness/firmness. Such features include soft sinking spots for the pelvic area in mattresses or for the counterpart ischium support zone in seat cushions. In distinction, firm and soft juxtapositions are provided for the upper thigh region in mattresses or in the counterpart femoral support zone in seat cushions. Conversely, firm lateral rails for mattresses or counterpart lateral wings for cushions of chair backs are provided where the concern is with Huntingdon's disease patients, who are largely immobile but periodically convulse at times.