Patents by Inventor David R. Rank

David R. Rank has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Articles having localized molecules disposed thereon and methods of producing same
    Patent number: 8193123
    Abstract: Methods of producing substrates having selected active chemical regions by employing elements of the substrates in assisting the localization of active chemical groups in desired regions of the substrate. The methods may include optical, chemical and/or mechanical processes for the deposition, removal, activation and/or deactivation of chemical groups in selected regions of the substrate to provide selective active regions of the substrate.
    Type: Grant
    Filed: October 26, 2007
    Date of Patent: June 5, 2012
    Assignee: Pacific Biosciences of California, Inc.
    Inventors: David R. Rank, Jeffery Wegener, Jonas Korlach, Daniel Roitman, Yue Xu, John Lyle, Stephen Turner, Paul Peluso, Geoff Otto, Ron Cicero
  • Polymerases for nucleotide analogue incorporation
    Publication number: 20110059505
    Abstract: Compositions that include polymerases with features for improving entry of nucleotide analogues into active site regions and for coordinating with the nucleotide analogues in the active site region are provided. Methods of making the polymerases and of using the polymerases in sequencing and DNA replication and amplification as well as kinetic models of polymerase activity and computer-implemented methods of using the models are also provided.
    Type: Application
    Filed: June 8, 2010
    Publication date: March 10, 2011
    Inventors: David K. Hanzel, Geoff Otto, Devon Murphy, Paul Peluso, Thang Pham, David R. Rank, Paul Mitsis, Fred Christians, Arek Bibillo, Insil Park, Sonya Clark, John Lyle
  • Preparations, Compositions, and Methods for Nucleic Acid Sequencing
    Publication number: 20100081143
    Abstract: Preparations, compositions and methods of sequencing nucleic acids are provided. The preparations, methods and compositions employ multiple priming sites on a target nucleic acid and typically utilize single molecule sequencing processes to identify sequence portions of the target which are then assembled to obtain the sequence of the target.
    Type: Application
    Filed: September 3, 2009
    Publication date: April 1, 2010
    Applicant: Pacific Biosciences of California, Inc.
    Inventors: David R. Rank, Paul Peluso
  • Articles having localized molecules disposed thereon and methods of producing same
    Publication number: 20080176769
    Abstract: Methods of producing substrates having selected active chemical regions by employing elements of the substrates in assisting the localization of active chemical groups in desired regions of the substrate. The methods may include optical, chemical and/or mechanical processes for the deposition, removal, activation and/or deactivation of chemical groups in selected regions of the substrate to provide selective active regions of the substrate.
    Type: Application
    Filed: October 26, 2007
    Publication date: July 24, 2008
    Applicant: Pacific Biosciences of California, Inc.
    Inventors: David R. Rank, Jeffery Wegener, Jonas Korlach, Daniel Roitman, Yue Xu, John Lyle, Stephen Turner, Paul Peluso, Geoff Otto
  • METHODS AND APPARATUS FOR PREDICTING, CONFIRMING, AND DISPLAYING FUNCTIONAL INFORMATION DERIVED FROM GENOMIC SEQUENCE
    Publication number: 20020081590
    Abstract: Methods and apparatus for predicting, confirming and displaying functional regions from genomic sequence data are presented. The methods and apparatus are particularly useful for predicting coding regions within genomic sequence data, confirming the expression thereof experimentally, and relating and displaying the expression data in meaningful relationship to the genomic sequence. The methods and apparatus of the present invention thus present powerful tools for novel gene discovery.
    Type: Application
    Filed: January 29, 2001
    Publication date: June 27, 2002
    Applicant: AEOMICA, INC.
    Inventors: Sharron G. Penn , David R. Rank , David K. Hanzel
  • Myosin-like gene expressed in human heart and muscle
    Publication number: 20020048800
    Abstract: Presented are a novel myosin-like protein particularly expressed in human heart and muscle, isolated nucleic acids encoding the myosin-like protein, compounds and compositions derivable directly or indirectly therefrom, and diagnostic and therapeutic methods for using the same.
    Type: Application
    Filed: May 25, 2001
    Publication date: April 25, 2002
    Inventors: Yizhong Gu, Yonggang Ji, Sharron G. Penn, David K. Hanzel, David R. Rank, Wensheng Chen, Mark E. Shannon