Patents by Inventor David Reed Powell

David Reed Powell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibodies that bind Notum Pectinacetylesterase
    Patent number: 11059907
    Abstract: Antibodies that neutralize Notum Pectinacetylesterase are described, as well as compositions comprising them, and methods of their use to treat diseases and disorders affecting the bone.
    Type: Grant
    Filed: February 15, 2019
    Date of Patent: July 13, 2021
    Assignee: Lexicon Pharmaceuticals, Inc.
    Inventors: Robert Joseph Brommage, Jr., Xiao Feng, Seokjoo Hong, Gregory Landes, Jeff Liu, David George Potter, David Reed Powell
  • ANTIBODIES THAT BIND NOTUM PECTINACETYLESTERASE
    Publication number: 20190241677
    Abstract: Antibodies that neutralize Notum Pectinacetylesterase are described, as well as compositions comprising them, and methods of their use to treat diseases and disorders affecting the bone.
    Type: Application
    Filed: February 15, 2019
    Publication date: August 8, 2019
    Applicant: Lexicon Pharmaceuticals, Inc.
    Inventors: Robert Joseph Brommage, JR., Xiao Feng, Seokjoo Hong, Gregory Landes, Jeff Liu, David George Potter, David Reed Powell
  • ANTIBODIES THAT BIND NOTUM PECTINACETYLESTERASE
    Publication number: 20160152731
    Abstract: Antibodies that neutralize Notum Pectinacetylesterase are described, as well as compositions comprising them, and methods of their use to treat diseases and disorders affecting the bone.
    Type: Application
    Filed: November 25, 2015
    Publication date: June 2, 2016
    Applicant: Lexicon Pharmaceuticals, Inc.
    Inventors: Robert Joseph Brommage, JR., Xiao Feng, Seokjoo Hong, Gregory Landes, Jeff Liu, David George Potter, David Reed Powell
  • METHODS OF LOWERING BLOOD PRESSURE
    Publication number: 20160022718
    Abstract: Methods of improving the cardiovascular and/or metabolic health of patients, particularly those suffering from type 2 diabetes, are disclosed, as well as compounds and pharmaceutical compositions useful therein.
    Type: Application
    Filed: October 6, 2015
    Publication date: January 28, 2016
    Inventors: Philip Manton Brown, Joel Philip Freiman, David Reed Powell
  • METHODS OF LOWERING BLOOD PRESSURE
    Publication number: 20140018308
    Abstract: Methods of improving the cardiovascular and/or metabolic health of patients, particularly those suffering from type 2 diabetes, are disclosed, as well as compounds and pharmaceutical compositions useful therein.
    Type: Application
    Filed: June 10, 2013
    Publication date: January 16, 2014
    Inventors: Philip Manton Brown, Joel Philip Freiman, David Reed Powell
  • Monoclonal antibodies against ANGPTL4
    Patent number: 8591891
    Abstract: Monoclonal antibodies that specifically bind to ANGPTL4 are provided. Monoclonal antibodies that neutralize at least one activity of ANGPTL4 are provided. Methods of treating a disorder of lipid metabolism using neutralizing monoclonal antibodies are provided.
    Type: Grant
    Filed: December 8, 2011
    Date of Patent: November 26, 2013
    Assignee: Lexicon Pharmaceuticals, Inc.
    Inventors: E-Chiang Lee, Gregory M. Landes, Kyu Chung, Ling Chen, Urvi Desai, David Reed Powell, Seokjoo Hong
  • ANTIBODIES THAT BIND NOTUM PECTINACETYLESTERASE
    Publication number: 20130302346
    Abstract: Antibodies that neutralize Notum Pectinacetylesterase are described, as well as compositions comprising them, and methods of their use to treat diseases and disorders affecting the bone.
    Type: Application
    Filed: November 22, 2011
    Publication date: November 14, 2013
    Applicant: LEXICON PHARMACEUTICALS, INC.
    Inventors: Robert Joseph Brommage, JR., Xiao Feng, Seokjoo Hong, Gregory Landes, Jeff Liu, David George Potter, David Reed Powell
  • Monoclonal Antibodies Against ANGPTL4
    Publication number: 20120171217
    Abstract: Monoclonal antibodies that specifically bind to ANGPTL4 are provided. Monoclonal antibodies that neutralize at least one activity of ANGPTL4 are provided. Methods of treating a disorder of lipid metabolism using neutralizing monoclonal antibodies are provided.
    Type: Application
    Filed: December 8, 2011
    Publication date: July 5, 2012
    Applicant: LEXICON PHARMACEUTICALS, INC.
    Inventors: E-Chiang Lee, Gregory M. Landes, Kyu Chung, Ling Chen, Urvi Desai, David Reed Powell, Seokjoo Hong
  • Monoclonal antibodies against ANGPTL4
    Patent number: 8092796
    Abstract: Monoclonal antibodies that specifically bind to ANGPTL4 are provided. Monoclonal antibodies that neutralize at least one activity of ANGPTL4 are provided. Methods of treating a disorder of lipid metabolism using neutralizing monoclonal antibodies are provided.
    Type: Grant
    Filed: December 4, 2009
    Date of Patent: January 10, 2012
    Assignee: Lexicon Pharmaceuticals, Inc.
    Inventors: E-Chiang Lee, Gregory M. Landes, Kyu Chung, Ling Chen, Urvi Desai, David Reed Powell, Seokjoo Hong
  • METHODS OF USING INHIBITORS OF SODIUM-GLUCOSE COTRANSPORTERS 1 AND 2
    Publication number: 20110218159
    Abstract: Methods of improving the cardiovascular and/or metabolic health of patients, particularly those suffering from type 2 diabetes, are disclosed, as well as compounds and pharmaceutical compositions useful therein.
    Type: Application
    Filed: March 1, 2011
    Publication date: September 8, 2011
    Inventors: Philip Manton Brown, Joel Philip Freiman, David Reed Powell
  • MONOCLONAL ANTIBODIES AGAINST ANGPTL4
    Publication number: 20110008359
    Abstract: Monoclonal antibodies that specifically bind to ANGPTL4 are provided. Monoclonal antibodies that neutralize at least one activity of ANGPTL4 are provided. Methods of treating a disorder of lipid metabolism using neutralizing monoclonal antibodies are provided.
    Type: Application
    Filed: December 4, 2009
    Publication date: January 13, 2011
    Applicant: LEXICON PHARMACEUTICALS, INC.
    Inventors: E-Chiang LEE, Gregory M. LANDES, Kyu CHUNG, Ling CHEN, Urvi DESAI, David Reed POWELL, Seokjoo HONG
  • Monoclonal antibodies against ANGPTL4
    Patent number: 7655762
    Abstract: Monoclonal antibodies that specifically bind to ANGPTL4 are provided. Monoclonal antibodies that neutralize at least one activity of ANGPTL4 are provided. Methods of treating a disorder of lipid metabolism using neutralizing monoclonal antibodies are provided.
    Type: Grant
    Filed: January 6, 2006
    Date of Patent: February 2, 2010
    Assignee: Lexicon Pharmaceuticals, Inc.
    Inventors: E-Chiang Lee, Gregory M. Landes, Kyu Chung, Ling Chen, Urvi Desai, David Reed Powell, Seokjoo Hong
  • Novel human membrane proteins and polynucleotides encoding the same
    Publication number: 20080102520
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Application
    Filed: February 17, 2006
    Publication date: May 1, 2008
    Inventors: Alejandro Abuin, Michael B. Burnett, Emily B. Cullinan, Gregory Donoho, Dorit B. Donoviel, Carl Johan Friddle, Glenn Friedrich, Brenda Gerhardt, Erin Hilbun, Yi Hu, Brian Mathur, Maricar Miranda, Michael C. Nehls, Boris Nepomnichy, David George Potter, David Reed Powell, Arthur T. Sands, John Scoville, Hong Sun, C. Alexander Turner, D. Wade Walke, Frank Wattler, Nathaniel L. Wilganowski, Xuanchuan Yu, Brian Zambrowicz