Abstract: The present invention relates to a pre-mix and a pharmaceutical composition for oxygenating a subject's tissues, uses and methods of treatment thereof.

Abstract: A method and system for processing a fixed format short message service (SMS) text message for alerting a user of a mobile phone to significant information in the message received by the mobile phone. Program code stored in memory on the mobile phone executes the method on a processor. A value of each preset variable of at least two preset variables is retrieved from the memory on the mobile phone. The mobile phone receives the message from a sender. The message is ascertained to be significant by ascertaining that the received message passes at least one test. Each test utilizes at least one aspect of the received message and the retrieved value of at least one preset variable. Responsive to the ascertaining, default handset settings of the mobile phone are overridden and the user is alerted by an audio tone or vibration that the received message is significant.

Abstract: A phantom, and a method and system for scanning the phantom, is provided for assessing the performance of ultrasound scanners. The phantom has tissue mimicking material (TMM) sections with different backscatter properties. The resolution of the scanner is assessed by measuring the response of the system to a step change in backscatter. Penetration and sensitivity of the scanner can also be assessed by measuring backscatter properties. Layers of the phantom can comprise lesions to enable quantification of the lesion detection performance of the scanner. The scanner can also comprise regularly spaced targets to enable assessment of the distance measurement accuracy of the scanner.

Abstract: The invention relates to nitrogen-containing heterocyclic compounds of general formula (I) wherein: R1 represents a (CH2)n—NH2 radical, n being equal to 1 or 2; R2 represents a hydrogen atom; R3 and R4 form together a nitrogen-containing heterocycle with aromaticity with 5 apices containing 1, 2 or 3 nitrogen atoms, substituted on this nitrogen atom or one of these nitrogen atoms with a (CH2)m—(C(O))p—R5 group, m being equal to 0, 1, 2 or 3, p being equal to 0 or 1 and R5 representing a hydroxy group, in which case p is equal to 1, or an amino, (C1-C6)alkyl or di-(C1-C6)alkyl amino, a nitrogen-containing heterocycle with aromaticity with 5 or 6 apices containing 1 or 2 nitrogen atoms and if necessary, an oxygen or sulfur atom; it being understood that when the sub-group (C(O))p—R5 forms a carboxy, amino, (C1-C6) alkyl or di-(C1-C6) alkyl amino, group, m is different from 0 or 1; in free form or as zwitterions and salts with pharmaceutically acceptable mineral or organic bases and acids, to their prepara

Abstract: A method and system for processing a free format short message service (SMS) text message for alerting a mobile phone's user to significant information in the message received by the mobile phone from a sender. Program code stored in memory on the mobile phone executes the method on a processor. A theme, a rheme, at least one structural component, and a sentence type of the normalized message are generated from which a FEATURE FACTOR priority is determined. Semantic content of the normalized message is determined from which an EMOTIONAL FACTOR priority is determined. A TOTAL PRIORITY computed as a sum of the FEATURE FACTOR priority and the EMOTIONAL FACTOR priority is determined to exceed a predetermined threshold, from which it is determined that the received message is significant, which triggers overriding default handset settings of the mobile phone and alerting the user that the received message is significant.

Abstract: A method and system for processing a fixed format short message service (SMS) text message for alerting a user of a mobile phone to significant information in the message received by the mobile phone. Program code stored in memory on the mobile phone executes the method on a processor. A value of each preset variable of at least two preset variables is retrieved from the memory on the mobile phone. The mobile phone receives the message from a sender. The message is ascertained to be significant by ascertaining that the received message passes at least one test. Each test utilizes at least one aspect of the received message and the retrieved value of at least one preset variable. Responsive to the ascertaining, default handset settings of the mobile phone are overridden and the user is alerted by an audio tone or vibration that the received message is significant.

Abstract: The present invention relates to a pre-mix and a pharmaceutical composition for oxygenating a subject's tissues, uses and methods of treatment thereof.

Abstract: Provided is a training method comprising delivering a situation to a learner, the situation comprising an event; automatically inserting a still menu in order to simulate a pause in the delivering; while pausing, recording an action by the learner in response to the event; reviewing the action recorded by the learner; and presenting to the learner a preferred action by a master in response to the event.

Abstract: A truss system and method for use in constructing a building structure comprising a first and second truss member connected to one another a distal end thereof thereby forming a peak joint. A cross bar is connected to each of the first and second truss members at an under side of the peak joint and a sleeve is connected to each of the first truss member and the second truss member at an end opposite the peak joint. Upon securing the cross bar to the first and second truss members, a truss unit is formed wherein a support member is received by the sleeves of each one of the truss units, and upon securing the support members to one another, the truss units form a frame of the building structure.

Abstract: The invention relates to new heterocyclic compounds of general formula (I), and their salts with a base or an acid: The invention also relates to a process for the preparation of these compounds as well as their use as medicaments, in particular as anti-bacterial agents.

Abstract: The hepatitis B virus (HBV) capsid is made up of a single species of protein called the core antigen (HBcAg) which self-assembles into particles. The particles are highly immunogenic and are able to present heterologous epitopes to the immune system when the epitopes are inserted into a surface-exposed region of the particles called the “e1 loop”. The structural building blocks of the particles are tightly associated dimers of HBcAg in which the adjacent e1 loops are closely juxtaposed. It is proposed that sequences inserted into the e1 loop are conformationally restrained in the assembled particles when presented in monomeric core protein. The invention seeks to solve this problem by covalently linking core proteins as tandem copies (e.g., as dimers) so that insertions can be made independently in each copy.

Abstract: Provided is a method for training/learning comprising delivering a situation to a learner, the situation comprising an event; automatically inserting a still menu in order to simulate a pause in the delivering; while pausing, recording an action by the learner in response to the event; reviewing the action recorded by the learner; and presenting to the learner a preferred action by a master in response to the event. A further method is provided comprising alternating between a motion menu and still menu in order to simulate a pause in a video where the background of the still menu is the same as the last frame of the motion menu; and during the pause, recording a learner's action in response to an event delivered in the video. Also provided is a system for training and learning comprising a learner video delivery tool; a video delivery medium; a learner control; an interactive pause; and a learner video recording tool.

Abstract: The present invention relates to the use of hepatitis C virus (HCV) p7 protein, and particularly but not exclusively, to its use in rationalised drug design and as a screen for antiviral therapeutic agents.

Abstract: A transgenic non-human animal whose genome comprises a polynucleotide encoding human ICAM-1 domains D1 and D2 and preferably encoding human ICAM-1 domains D1 and D2 and host non-human ICAM-1 domains D3, D4 and D5. Methods for the production of such transgenic animals, screening methods using such transgenic animals, associated transgenes, constructs, vectors, and cells are disclosed. The transgenic non-human animal is a suitable model for studying human rhinovirus infection.

Abstract: The invention relates to new heterocyclic compounds of general formula (I), and their salts with a base or an acid: The invention also relates to a process for the preparation of these compounds as well as their use as medicaments, in particular as anti-bacterial agents.

Abstract: A method for conducting an interactive financial simulation. The method is implemented at least in part by a computer and includes transmitting an initial financial projection for a fictitious company, transmitting a news story, generating a new share price for the fictitious company based on an index, generating a new financial projection for the fictitious company based on a set of decisions selected for implementation by a participant of the interactive financial simulation, and generating a final share price for the fictitious company based on a final set of decisions selected for implementation by the participant.

Abstract: The invention relates to new heterocyclic compounds of general formula (I), and their salts with a base or an acid: The invention also relates to a process for the preparation of these compounds, as well as their use as medicaments, in particular as anti-bacterial agents.

Abstract: This invention discloses and claims methods for inhibiting bacterial ?-lactamases and treating bacterial infections by inhibiting bacterial ?-lactamases in man or an animal comprising administering a therapeutically effective amount to said man or said animal of a compound, or pharmaceutically acceptable salt thereof, of formula (I) either alone or in combination with a ?-lactamine antibiotic wherein said combination can be administered separately, together or spaced out over time. Pharmaceutical compositions comprising a compound of formula (I), or a combination of a compound of formula (I) and a therapeutically effective amount of a ?-lactamine antibiotic, and a pharmaceutically acceptable carrier are also disclosed and claimed.

Abstract: The hepatitis B virus (HBV) capsid is made up of a single species of protein called the core antigen (HBcAg) which self-assembles into particles. The particles are highly immunogenic and are able to present heterologous epitopes to the immune system when the epitopes are inserted into a surface-exposed region of the particles called the “el loop”. The structural building blocks of the particles are tightly associated dimers of HBcAg in which the adjacent el loops are closely juxtaposed. It is proposed that sequences inserted into the el loop are conformationally restrained in the assembled particles when presented in monomeric core protein. The invention seeks to solve this problem by covalently linking core proteins as tandem copies, e.g., as dimers, so that insertions can be made independently in each copy.