Abstract: The present invention features antibodies that have high binding affinity to human neonatal Fc receptor (FcRn). These anti-FcRn antibodies are useful, e.g., to promote clearance of autoantibodies in a subject, to suppress antigen presentation in a subject, to block an immune response, e.g., block an immune complex-based activation of the immune response in a subject, and to treat immunological diseases (e.g., autoimmune diseases) in a subject.

Abstract: A proxy device comprising a processor and a communication interface communicatively coupled to the processor. The communication interface configured to transmit information representative of a second security protocol to a remote control. The remote control operable to transmit communications to a movable barrier operator utilizing a first security protocol. In response to transmitting the information representative of the second security protocol to the remote control, the communication interface receives a first acknowledgement communication from the remote control indicating the remote control utilizes the second security protocol.

Abstract: A prosthetic joint and a method of controlling dorsiflexion and plantarflexion of the hydraulic prosthetic ankle joint. The method includes generating ground reaction forces with a hydraulic prosthetic ankle, wherein the prosthetic hydraulic ankle comprises a first chamber and a second chamber, and the ankle is connected to a prosthetic foot; rotating the prosthetic foot in response to the ground reaction force; transferring fluid between the forward and rear chambers in response to rotation of the foot; providing a feature to occlude or partially occlude the fluid transfer between chambers; providing a non-electronic mechanism for controlling the flow responsive to both a position of the joint and a rate of change of position of the joint, and wherein the mechanism is arranged such that a dwell at a particular joint location or locations will occlude the flow path.

Abstract: Provided herein are methods, compositions and uses involving T cell therapies, such as adoptive T cell therapy, and an inhibitor of a Diacylglycerol kinase (DGK). The provided methods, compositions and uses include those involving the administration or use of one or more DGK inhibitors (DGKi) in a combination therapy with a T cell therapy, such as a genetically engineered T cell therapy involving cells engineered with a recombinant receptor, such as chimeric antigen receptor (CAR) or T cell receptor (TCR).

Abstract: Remote automated assistant component(s) generate client device notification(s) based on a received IoT state change notification that indicates a change in at least one state associated with at least one IoT device. The generated client device notification(s) can each indicate the change in state associated with the at least one IoT device, and can optionally indicate the at least one IoT device. Further, the remote automated assistant component(s) can identify candidate assistant client devices that are associated with the at least one IoT device, and determine whether each of the one or more of the candidate assistant client device(s) should render a corresponding client device notification.

Abstract: An electronic messaging device includes a receiver configured to receive a message at one of a first operational frequency and second operational frequency. The messaging device can operate using a time synchronous protocol and can receive commands through over-the-internet-programming (OTIP) and over-the-air-programming (OTAP).

Abstract: The present invention relates to a synergistic combination of an FXR agonist and interferon for the treatment of hepatitis B.

Abstract: Disclosed herein is one or more subtilisin variant, nucleic acid encoding same, and compositions and methods related to the production and use thereof, including one or more subtilisin variant that has improved stability and/or soil removal compared to one or more reference subtilisin.

Abstract: Systems and methods are provided for creating and executing a decision network that includes a number of stations configured to operate with respect to an instance of a document, container or other object. A user interface may be presented to a user that includes selectable options for configuring and connecting stations within the decision network, and for establishing executable logic for each station to modify or create data within fields of a container instance. Different stations in the decision network may be assigned different permissions with respect to the container. Individual stations in the decision network may be configured to determine a prediction or probability based on data accessible to the given station, where the prediction or probability of one station may be based in part on an earlier prediction or probability determined at another station of the decision network.

Abstract: Efficient control and/or linking of smart network connected devices. Some implementations are directed to rendering, within an active application that enables control of multiple smart devices from multiple parties, both: (1) an interactive graphical interface element that, when interacted with, causes corresponding control of smart device(s) of a third-party (3P); and (2) a selectable element that, when selected, causes execution of a deeplink to cause a 3P application to open in a state that presents additional information for the smart device(s). Some implementations are additionally or alternatively directed to, in response to determining that a 3P application is installed at a client device, but a smart device topology lacks any entries for 3P smart devices of the 3P, efficiently adding one or more particular smart devices of the 3P to the smart device topology.

Abstract: In one example, a method includes receiving audio data generated by one or more microphones of a computing device, the audio data representing a spoken utterance; identifying, based on the audio data, a user that provided the spoken utterance; identifying, based on the audio data, an automation action associated with one or more automation devices, the automation action corresponding to the spoken utterance; determining whether the identified user is authorized to cause performance of the identified automation action; and responsive to determining that the identified user is authorized to cause performance of the identified automation action, causing the one or more automation devices to perform the identified automation action.

Abstract: Various implementations relate to techniques, for controlling smart devices, that are low latency and/or that provide computational efficiencies (client and/or server) and/or network efficiencies. Those implementations relate to generating and/or utilizing cache entries, of a cache that is stored locally at an assistant client device, in control of various smart devices (e.g., smart lights, smart thermostats, smart plugs, smart appliances, smart routers, etc.). Each of the cache entries includes a mapping of text to one or more corresponding semantic representations.

Abstract: In one example, a method includes receiving audio data generated by one or more microphones of a computing device, the audio data representing a spoken utterance; identifying, based on the audio data, a user that provided the spoken utterance; identifying, based on the audio data, an automation action associated with one or more automation devices, the automation action corresponding to the spoken utterance; determining whether the identified user is authorized to cause performance of the identified automation action; and responsive to determining that the identified user is authorized to cause performance of the identified automation action, causing the one or more automation devices to perform the identified automation action.

Abstract: Efficient control and/or linking of smart network connected devices. Some implementations are directed to rendering, within an active application that enables control of multiple smart devices from multiple parties, both: (1) an interactive graphical interface element that, when interacted with, causes corresponding control of smart device(s) of a third-party (3P); and (2) a selectable element that, when selected, causes execution of a deeplink to cause a 3P application to open in a state that presents additional information for the smart device(s). Some implementations are additionally or alternatively directed to, in response to determining that a 3P application is installed at a client device, but a smart device topology lacks any entries for 3P smart devices of the 3P, efficiently adding one or more particular smart devices of the 3P to the smart device topology.

Abstract: Various implementations relate to generating, locally at an assistant client device, specific control commands that, when transmitted to a corresponding smart device, are directly interpretable by the corresponding smart device to effectuate a state change at the corresponding smart device, or at a corresponding additional smart device directly controlled by the corresponding smart device. Various implementations additionally or alternatively relate to utilizing local assistant client devices in discovering, provisioning, and/or registering smart devices for an account of a user.

Abstract: The present disclosure provides systems and methods that perform structure-based access control. In particular, rather than relying upon a user-specific credential scheme, which can require manual sharing of user-specific credentials and/or switching between the multiple accounts to access the particular devices, applications, or services associated with such accounts, the systems and methods of the present disclosure facilitate user credentials to be inherited by or otherwise assigned to a structure identifier associated with a structure (e.g., a home in which the user resides), thereby generating a set of structure credentials. This enables other users in the structure, who may be part of a collaborative user group, to access devices, applications, and/or services using the structure credentials.

Abstract: Various implementations relate to techniques, for controlling smart devices, that are low latency and/or that provide computational efficiencies (client and/or server) and/or network efficiencies. Those implementations relate to generating and/or utilizing cache entries, of a cache that is stored locally at an assistant client device, in control of various smart devices (e.g., smart lights, smart thermostats, smart plugs, smart appliances, smart routers, etc.). Each of the cache entries includes a mapping of text to one or more corresponding semantic representations.

Abstract: The vectorial magnetometer and associated methods can allow to distinguish the relative superposed amplitudes associated to different spin populations based on the known proportions of the Rabi attenuation in the different characteristic orientations of the spin populations due to application of different pulse parameters which can be specifically selected to create a contrast between the attenuation proportions stemming from the different spin populations.

Abstract: Methods, apparatus, systems, and computer-readable media are provided for tailoring composite graphical assistant interfaces for interacting with multiple different connected devices. The composite graphical assistant interfaces can be generated in response to a user providing a request for an automated assistant to cause a connected device to perform a particular function. In response to the automated assistant receiving the request, the automated assistant can identify other connected devices, and other functions capable of being performed by the other connected devices. The other functions can then be mapped to various graphical control elements in order to provide a composite graphical assistant interface from which the user can interact with different connected devices. Each graphical control element can be arranged to reflect how each connected device is operating simultaneous to the presentation of the composite graphical assistant interface.

Abstract: The present disclosure provides systems and methods that perform structure-based access control. In particular, rather than relying upon a user-specific credential scheme, which can require manual sharing of user-specific credentials and/or switching between the multiple accounts to access the particular devices, applications, or services associated with such accounts, the systems and methods of the present disclosure facilitate user credentials to be inherited by or otherwise assigned to a structure identifier associated with a structure (e.g., a home in which the user resides), thereby generating a set of structure credentials. This enables other users in the structure, who may be part of a collaborative user group, to access devices, applications, and/or services using the structure credentials.