Abstract: The invention is directed to plastisol coating formulations for agricultural uses. The plastisol-coated agrochemicals comprise a coating formed from a plastisol formulation, wherein the plastisol formulation comprises a suspension of polymer particles in a liquid plasticizer, and a solid agrochemical, wherein the coating is applied to the solid agrochemical and cured to form a film thereupon.

Abstract: The invention encompasses therapeutic formulations comprising a protein active ingredient and a stabilizing excipient, methods of improving stability in a therapeutic formulation comprising a protein active ingredient by adding a stability-improving amount of a stabilizing excipient to the therapeutic formulation, and methods of reducing adverse infusion-related effects in a patient, comprising administering to a patient in need thereof a therapeutic formulation comprising a protein active ingredient and a stabilizing excipient.

Abstract: Disclosed herein are methods for improving a parameter of a protein-related process comprising providing a viscosity-reducing excipient compound selected from the group consisting of hindered amines, anionic aromatics, functionalized amino acids, oligopeptides, short-chain organic acids, and low molecular weight aliphatic polyacids, and adding a viscosity-reducing amount of the viscosity-reducing excipient compound to a carrier solution for the protein-related process, wherein the carrier solution contains a protein of interest, and carrier solutions comprising a liquid medium in which is dissolved a protein of interest, and a viscosity-reducing excipient, wherein the viscosity of the carrier solution has a lower viscosity that that of a control solution that is substantially similar to the carrier solution except for the presence of the viscosity-reducing excipient.

Abstract: The invention provides for modified proppants, comprising a proppant particle and a hydrogel coating, wherein the hydrogel coating localizes on the surface of the proppant particle to produce the modified proppant, methods of manufacturing such proppants and methods of use.

Abstract: The invention encompasses therapeutic formulations comprising a protein active ingredient and a stabilizing excipient, methods of improving stability in a therapeutic formulation comprising a protein active ingredient by adding a stability-improving amount of a stabilizing excipient to the therapeutic formulation, and methods of reducing adverse infusion-related effects in a patient, comprising administering to a patient in need thereof a therapeutic formulation comprising a protein active ingredient and a stabilizing excipient.

Abstract: The invention provides formulations for facilitating the removal of oil from a surface using a chisel composition, wherein the chisel composition includes a polymer having one or more binding points with a high affinity for the surface, and one or more hydrophilic segments that form a hydrophilic coating on the surface, rendering the surface water-wet and thereby facilitating the removal of oil from the surface. The invention also provides for methods of use of such formulations.

Abstract: A self-suspending proppant comprises a proppant substrate particle and a water-swellable composite coating on the proppant substrate particle comprising the combination of at least two of an anionic hydrogel polymer, a cationic hydrogel polymer and a nonionic hydrogel polymer.

Abstract: The present invention provides modified proppants, and methods for their manufacture. In embodiments, the modified proppant comprises a proppant particle and a hydrogel coating, wherein the hydrogel coating is applied to a surface of the proppant particle and localizes on the surface to produce the modified proppant. In embodiments, formulations are disclosed comprising the modified particles, and methods are disclosed for using the formulations.

Abstract: Both the inside surface and the outside surface of the hydrogel polymer coating of a self-suspending proppant are surface crosslinked.

Abstract: A self-suspending proppant comprises a proppant particle substrate carrying a coating of an anionic hydrogel-forming polymer. The detrimental effect of calcium and other divalent ions on the ability of the proppant to swell when contacted with water is reduced by including a calcium binding agent in the proppant.

Abstract: The invention is directed to systems and methods of removing particulate matter from a fluid, comprising: pre-activating the particulate matter to form a pre-activated particulate matter; providing an activating material capable of being affixed to the pre-activated particulate matter; affixing the activating material to the pre-activated particulate matter to form an activated particle; providing an anchor particle and providing a tethering material capable of being affixed to the anchoring particle; and attaching the tethering material to the anchor particle and the activated particle to form a removable complex in the fluid that comprises the particulate matter, wherein the particulate matter is derived from a mining operation.

Abstract: Systems and methods are presented for removing an ionic material from a fluid using a capture polymer that sequesters the ionic material and an anchor particle bearing a tethering polymer. The tethering polymer complexes with the capture polymer after the capture polymer has sequestered the ionic material, thereby affixing a complex of capture polymer and ionic material to the anchor particle to form a removable complex. The removable material can be segregated from the fluid via a removal system, thereby removing the ionic material from the fluid.

Abstract: The invention provides for modified proppants, comprising a proppant particle and a hydrogel coating, wherein the hydrogel coating localizes on the surface of the proppant particle to produce the modified proppant, methods of manufacturing such proppants and methods of use.

Abstract: The invention encompasses a nontoxic agricultural formulation of a concentrated liquid suspension comprising an organic phase and suspended particulate materials, and also encompasses an aqueous formulation comprising the concentrated liquid suspension and an agricultural treatment agent. The invention additionally encompasses methods of treating an agricultural target, comprising providing an agricultural formulation of a concentrated liquid suspension comprising an organic phase and suspended particulates, and applying the agricultural formulation onto the agricultural target, thereby treating the agricultural target.

Abstract: The invention encompasses therapeutic formulations comprising a protein active ingredient and a stabilizing excipient, methods of improving stability in a therapeutic formulation comprising a protein active ingredient by adding a stability-improving amount of a stabilizing excipient to the therapeutic formulation, and methods of reducing adverse infusion-related effects in a patient, comprising administering to a patient in need thereof a therapeutic formulation comprising a protein active ingredient and a stabilizing excipient.

Abstract: The invention encompasses therapeutic formulations comprising a protein active ingredient and a stabilizing excipient, methods of improving stability in a therapeutic formulation comprising a protein active ingredient by adding a stability-improving amount of a stabilizing excipient to the therapeutic formulation, and methods of reducing adverse infusion-related effects in a patient, comprising administering to a patient in need thereof a therapeutic formulation comprising a protein active ingredient and a stabilizing excipient.

Abstract: The invention provides for modified proppants, comprising a proppant particle and a hydrogel coating, wherein the hydrogel coating localizes on the surface of the proppant particle to produce the modified proppant, methods of manufacturing such proppants and methods of use.

Abstract: The invention encompasses formulations and methods for the production thereof that permit the delivery of concentrated protein solutions. The inventive methods can yield a lower viscosity liquid formulation or a higher concentration of therapeutic or nontherapeutic proteins in the liquid formulation, as compared to traditional protein solutions.

Abstract: The present invention relates to formulations comprising an inversion facilitator additive and an active emulsion polymer, and methods for their use. The formulation can comprise a water-in-oil emulsion having the active emulsion polymer in an aqueous phase of the water-in-oil emulsion. The active emulsion polymer can be a friction-reducing polymer, a flocculant polymer, or any other polymer suitable for delivery within the aqueous phase of the water-in-oil emulsion.

Abstract: The present invention provides modified proppants, and methods for their manufacture. In embodiments, the modified proppant comprises a proppant particle and a hydrogel coating, wherein the hydrogel coating is applied to a surface of the proppant particle and localizes on the surface to produce the modified proppant. In embodiments, formulations are disclosed comprising the modified particles, and methods are disclosed for using the formulations.